Clinical trials
Depression clinical trials
A common mood disorder causing persistent sadness and loss of interest. We’re tracking 1,419 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07369180Enrolling by invitation
TMS for treatment-resistant depression in adults
This study tests a new type of transcranial magnetic stimulation (TMS) for adults whose depression hasn't gotten better with medication. It compares the real treatment to a sham (inactive) version to see how well it works.
Campbell, CaliforniaAges 22–85 - NCT07364799Recruiting
Sound therapy for stress in detained teens
This trial tests a multi-sensory therapy called SoundHeal for teens in juvenile detention. It uses sound and vibration to help with stress, anxiety, depression, or substance use.
San Luis Obispo, CaliforniaAges 12–18 - NCT06512025Recruiting
Education program for first-time new mothers
This study tests whether a short education program (psychoeducational intervention) can help new first-time moms feel more confident and supported after childbirth. If you qualify, you would receive extra information and guidance during your postpartum checkups.
Barcelona, BarcelonaAges 18 years+ - NCT07360600Recruiting
Web-based parent support program with coaching
This study tests a web-based program with brief coaching to help parents of children with disabilities manage stress and emotions. Participation involves using the program and talking with a coach, and you must have internet access and a child who visits a clinic regularly.
Tampa, FloridaAges 18 years+ - NCT07354334Enrolling by invitation
Listening to a Quranic surah after cesarean birth
This study tests if listening to Surah Al-Inshirah after a cesarean helps new mothers feel better. It looks at things like pain, anxiety, and recovery.
Konya, SelçukluAges 18–45 - NCT07359157Recruiting
Support program for WRCH patients with legal history
This study offers a group program at Worcester Recovery Center and Hospital (WRCH) aimed at helping people who have been involved with the legal system. It is designed for current patients at WRCH who are at least 18 years old and comfortable speaking English.
Worcester, MassachusettsAges 18 years+ - NCT06633146Recruiting
Stroke rehab in nature settings
This trial tests if stroke recovery exercises in natural environments can help improve your rehabilitation. It is for people who have had a recent stroke.
LahtiAges 18 years+ - NCT07346183Recruiting
Text messages and peer support for dementia caregivers
This study tests a program that sends helpful texts and connects you with a trained peer caregiver who has been through similar experiences. It aims to make caring for someone with dementia easier and less stressful.
Chicago, IllinoisAges 18 years+ - NCT07345858Enrolling by invitation
Saliva test for psychedelic depression treatment
This trial tests whether a simple saliva test can measure oxytocin levels during a psychedelic treatment for hard-to-treat depression. The goal is to find a biological marker that helps predict how well the therapy works.
GenevaAges 18 years+ - NCT07346014Recruiting
Sleep therapy for college students at risk of suicide
This study tests if improving sleep can help college students who are already getting mental health treatment for suicidal thoughts. You will try light therapy or sleep schedule changes to see if it reduces suicide risk.
Pittsburgh, PennsylvaniaAges 18–25 - NCT07345377Enrolling by invitation
Personalized brain stimulation for irritable bowel syndrome
This study uses brain stimulation (TMS) customized for each person to treat IBS. It uses MRI scans to see how the brain responds, aiming to find better ways to predict who will benefit from this therapy.
Hangzhou, ZhejiangAges 18–75 - NCT07351799Recruiting
Mindfulness and meditation for NICU moms' breast milk
This study tests whether mindfulness and meditation education helps mothers in the NICU produce more breast milk. If you join, you'll learn relaxation techniques and track your pumping routine.
Rochester, MinnesotaAges 20 years+ - NCT07347158Enrolling by invitation
Health education for ostomy patients
This study teaches people with an ostomy (a surgical opening for waste) about their health to improve their quality of life and reduce anxiety or depression. If you are an adult with a permanent or long-term ostomy and live in the Santiago or Barbanza area, you may be able to join.
Santiago de Compostela, A CoruñaAges 18 years+ - NCT06858189RecruitingPhase 2
Path to Wellness: therapy plus physical activity
This study combines talk therapy with a physical activity program to help treat depression or anxiety. It may help you feel better in both your mind and body.
Manhattan, KansasAges 18–65 - NCT07342569Recruiting
WeACT program for dementia caregivers
This study tests a program called WeACT designed to support family caregivers who are feeling down. It aims to help improve your mood and well-being through online sessions.
Tampa, FloridaAges 18 years+ - NCT07341425Recruiting
Focused therapy for stress, anxiety, and depression
This trial tests a short, online therapy program (Focused Acceptance and Commitment Therapy) designed to help you manage stress, anxiety, or depression. You can participate from home using a smartphone, tablet, or computer with a camera.
Aarhus CAges 18 years+ - NCT07340983Recruiting
Safe Haven app study for college students
This study tests if a smartphone app called Safe Haven can help college students feel better. If you are a student aged 18-24 with a smartphone, you might be able to join.
TainanAges 18–24 - NCT05898516Recruiting
JoyPop mental health app for Indigenous teens on a waitlist
This trial studies a mobile mental health app called JoyPop for Indigenous teens (ages 12–17) who are waiting to get mental health support. It may help by offering accessible support while they wait for services.
Thunder Bay, OntarioAges 12–17 - NCT06864156Recruiting
Molecules and vitamin levels in long COVID with brain fog
This study looks at certain molecules (called microRNAs) and vitamin B12 levels in people who have ongoing brain-related symptoms like depression, anxiety, or fatigue after a COVID-19 infection. It may help understand why some people have long-lasting symptoms and could lead to better treatments.
Mexico City, Mexico CityAges 18–65 - NCT03987633Recruiting
Study links health records and samples to understand health gaps
This study asks people affected by a specific illness (or their family member) to share saliva (and sometimes blood) and answer health and quality-of-life questions. The goal is to better understand and reduce health inequality by matching new information with medical records.
Wolverhampton, West MidlandsAges 6 years+ - NCT07319117Recruiting
Can a nutritional drink help your brain under stress?
This study tests whether a special nutritional drink can help your brain work better when you're under stress. If you're a healthy woman in her 40s or 50s who drinks coffee daily, you may be able to join.
Leeds, West YorkshireAges 40–60 - NCT07316803Recruiting
Group therapy for romantic relationships in young adults with mental illness
This study tests a group program to help young adults with serious mental health conditions build skills for romantic and social relationships. It may be a good fit if you are single, motivated to work on relationships, and have received mental health care recently.
Épinay-sur-Seine, Île-de-France RegionAges 18 years+ - NCT07317271Recruiting
Virtual reality for burn symptoms
This trial tests a virtual reality program to help with symptoms like pain, trouble sleeping, and itching after a burn injury. You can join from home using your own device.
Baltimore, MarylandAges 18 years+ - NCT07319143Recruiting
Can brain stimulation boost emotional health?
This trial uses a gentle brain stimulation technique called tDCS to see if it can improve emotional well-being. It is for healthy young adults who speak Cantonese or Mandarin.
Hong KongAges 18–35
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Common questions
- Are there clinical trials for depression?
- Yes. Clin2 currently lists 1,419 recruiting depression studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a depression trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a depression trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.