Clinical trials
Depression clinical trials
A common mood disorder causing persistent sadness and loss of interest. We’re tracking 1,509 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07107906Recruiting
CONNECT program: group telehealth to reduce loneliness in adults 55+
This trial tests a group-based telehealth program called CONNECT, which aims to reduce loneliness, social isolation, and mental health symptoms like anxiety or depression in adults aged 55 and older. You'll join online group sessions instead of in-person programs, making it easier to connect from home.
Winnipeg, ManitobaAges 55 years+ - NCT07111169Recruiting
Brain stimulation and attention in depression study
This study tests whether a non-invasive brain stimulation technique (called iTBS) can improve attention problems in people with major depression. If you have depression and trouble focusing, this trial might help understand a new treatment option.
Chengdu, SichuanAges 18–55 - NCT07113665RecruitingPhase 1
Focused ultrasound brain treatment for severe anorexia
This trial tests if focused ultrasound can help people with severe anorexia nervosa who also have obsessive-compulsive disorder or major depression. It is for those who have not gotten better with other treatments.
Toronto, OntarioAges 18–65 - NCT07115628Recruiting
Accelerated TMS for treatment-resistant depression
This trial tests an accelerated form of transcranial magnetic stimulation (TMS) for people with treatment-resistant depression who have been referred for ECT. It aims to offer a non-invasive, less intensive alternative with fewer side effects.
Jette, Brussels CapitalAges 18–70 - NCT07120711Recruiting
Sleep apnea, thinking, and mood study for kids and adults
This study looks at how sleep apnea affects thinking and mood by checking certain proteins in the body. They want to see if these proteins can help predict or explain changes in memory, focus, or emotions.
ShanghaiAges 5 years+ - NCT07129070Recruiting
Just-in-Time Training for Youth Mentors
This trial tests a new training program for mentors working with middle and high school students. It aims to help mentors better support youth who may be experiencing depression.
Minneapolis, MinnesotaAges 12 years+ - NCT07138664Recruiting
Mental health program for teens in Malaysia
This trial tests a program to help young teenagers in Malaysia who are experiencing anxiety or depression. The program aims to improve mental health and well-being.
Kota Kinabalu, SabahAges 12–14 - NCT07143357Recruiting
Mind-body recovery program for cardiac arrest survivors and their caregivers
This trial tests a mind-body program to help cardiac arrest survivors and their caregivers recover together after a cardiac arrest. It combines in-person and video sessions to reduce emotional distress and improve wellbeing.
Boston, MassachusettsAges 18 years+ - NCT07143539Recruiting
Early exercise rehab after hospital stay for pulmonary embolism
This study tests if starting a supervised exercise program early after a hospital stay for a blood clot in the lungs (pulmonary embolism) helps patients recover better and feel less breathless. It is for people at higher risk of ongoing symptoms after their clot.
AarauAges 18 years+ - NCT07151079Recruiting
Group therapy for trans teens feeling stressed
This study tests a group therapy program for teens who are trans or gender diverse and feeling stressed, anxious, or sad. The goal is to see if talking together in a group helps improve their well-being.
Parkville, VictoriaAges 12–17 - NCT07151573Recruiting
Big five intervention trial for mental health in Norway
This trial tests a program called the Big Five Intervention to help people with anxiety or depression symptoms. It is available for people living in Norway who are 16 or older.
Bergen, VestlandAges 16 years+ - NCT07155941Recruiting
App-based training for lack of pleasure
This trial tests if an app-based training program can help people who have trouble feeling pleasure from daily activities (anhedonia). It combines mood check-ins and simple, repeated exercises to retrain the brain's reward system.
Marburg, HesseAges 18 years+ - NCT07165925Recruiting
Music lessons to build resilience in children from low-income families
This study tests whether music training can help build emotional strength in children aged 8-12 from low-income families in Hong Kong. It specifically looks at children who may be at risk for depression or anxiety.
Hong KongAges 8–12 - NCT07167849Recruiting
Digital help while waiting for therapy
This trial tests a brief digital program for people waiting for outpatient therapy. It aims to provide support during the wait and see if it helps improve mental health symptoms.
BernAges 18 years+ - NCT07170657Recruiting
Teen Recovery Support Program
This program helps teens ages 15 to 18 who have recently been in the hospital or emergency room for suicidal thoughts or depression. It provides support and guidance to help you recover and feel stronger.
Dallas, TexasAges 15–18 - NCT07172607Recruiting
Can Avnace eZZe improve sleep?
This study tests a dietary supplement called Avnace eZZe to see if it helps improve sleep in adults with insomnia. You may be able to join if you have a diagnosis of insomnia and are not currently using sleep aids.
TaipeiAges 18 years+ - NCT07173205Recruiting
Coping toolkit for teens and young adults after cancer
This trial tests a mobile toolkit to help teens and young adults manage their emotions and cope better after finishing cancer treatment. It is designed for those who completed treatment 1 month to 5 years ago.
Greenville, North CarolinaAges 15–39 - NCT07176403Recruiting
Exercise During Dialysis for Better Sleep and Mood
This study tests whether gentle exercise during your regular dialysis sessions can improve sleep quality, reduce feelings of depression, and lower anxiety. If you are on dialysis and are generally physically able to move your legs, this may be a safe and helpful program for you.
AlexandriaAges 18 years+ - NCT07178873Recruiting
Online support program for adults with spina bifida
This study tests an online support program for adults with spina bifida to help with emotional and social well-being. It is done from home through video calls.
Bilbao, BizkaiaAges 18–75 - NCT07183826Recruiting
Online mindfulness therapy for chronic tinnitus
This trial tests an online mindfulness program (iMBCT) to help people with chronic tinnitus manage their symptoms. If you have had tinnitus for at least 3 months and it bothers you, you may be able to join from home.
WarsawAges 18 years+ - NCT07185815RecruitingPhase 1/Phase 2
Study of a long-acting cariprazine shot for mood and schizophrenia
This trial tests a monthly injection of cariprazine (a medication for mental health conditions) in people who could benefit from it. It aims to see if the shot is safe, tolerable, and effective compared to taking pills every day.
AhmedabadAges 18–64 - NCT07186816Recruiting
Peer support for Spanish-speaking adults with anxiety or depression
This trial tests whether peer support from someone who has been through similar struggles can help reduce anxiety and depression symptoms. It's for Spanish-speaking adults who have internet access and are not currently in talk therapy.
San Francisco, CaliforniaAges 18–100 - NCT07193823Recruiting
Sexual function study for women with MS
This study looks at sexual health in women with relapsing-remitting multiple sclerosis. It aims to understand how MS might affect sexual function and to find ways to help.
Izmir, BornovaAges 25–50 - NCT07198100Recruiting
Ear stimulation, motivation, and insulin sensitivity in depression
This study explores how a gentle electrical stimulation of the ear might affect mood, motivation, and insulin sensitivity in people with and without depression. It aims to see if this non-invasive technique could offer new ways to help with depression.
BonnAges 18–60
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Common questions
- Are there clinical trials for depression?
- Yes. Clin2 currently lists 1,509 recruiting depression studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a depression trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a depression trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.