Clinical trials
Depression clinical trials
A common mood disorder causing persistent sadness and loss of interest. We’re tracking 1,509 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07208851Recruiting
Booster session for mental health support in the Bahamas
This trial tests a short booster session for a mental health support program called Problem Management Plus. It may help adults in the Bahamas who are struggling with daily life but don't have severe mental health conditions.
Freeport, Grand BahamaAges 18 years+ - NCT07211217Recruiting
Time-restricted eating for bipolar depression
This study tests if eating only during a specific daily window can help with weight loss and mood in people with bipolar disorder who are currently depressed and overweight.
Boston, MassachusettsAges 18–65 - NCT07214597Recruiting
Using voice technology to improve NICU mom experience
This trial tests a smartphone app called VoiceLove that lets moms record their voice for their baby in the NICU. It may help mothers feel more connected and supported while their baby is in the hospital.
Nashville, TennesseeAges 18 years+ - NCT07218250Recruiting
Single counseling session for breast cancer distress
This trial tests whether one counseling session can reduce depression, anxiety, and distress in people with breast cancer. You would talk privately with a counselor and be audio-recorded.
Basking Ridge, New JerseyAges 18 years+ - NCT07219264Recruiting
Mental health first aid training for cancer survivors
This study offers a free training program called Mental Health CPR for cancer survivors and their supporters. It is designed to help Latino/Hispanic communities in southern Puerto Rico learn how to provide emotional first aid and mental health support to people affected by cancer.
Ponce, Puerto RicoAges 21–99 - NCT07219394Recruiting
Peer support for depression in community care
This trial tests if peer-delivered behavioral therapy can help adults with depression symptoms. If you are 18 or older and feel sad or down, this study may teach you practical ways to feel better.
Detroit, MichiganAges 18 years+ - NCT07221409Recruiting
Virtual reality to help cancer patients feel better during treatment
This trial tests whether using virtual reality can help reduce stress, anxiety, and other emotional symptoms in people being treated for cancer. Patients undergoing chemotherapy, bone marrow transplant, or CAR-T therapy may be eligible.
Jacksonville, FloridaAges 18–90 - NCT07227337Recruiting
Being safe, healthy, and empowered for immigrant women
This study tests a program to help immigrant women who have faced violence and feel symptoms of PTSD or depression. It aims to improve your safety, health, and wellbeing.
Baltimore, MarylandAges 18 years+ - NCT07228520Recruiting
Pain and strength study for depression and frailty
This trial tests a program to help people with chronic pain, depression, and weakness build strength and coping skills. It may help you if pain limits your daily activities and you feel down or frail.
Baltimore, MarylandAges 50 years+ - NCT07237009Recruiting
Personalized reminiscence therapy for memory loss
This trial tests a digital app that uses personal photos and memories to help people with early memory problems feel less depressed or apathetic. It's designed for seniors who have mild cognitive impairment or early dementia.
AngersAges 60 years+ - NCT07239609RecruitingPhase 1
ACT therapy for memory loss and their caregivers
This study tests if ACT, a type of talk therapy, helps people with mild memory loss and their care partners cope with difficult emotions. Both you and a family member or friend who helps you would participate.
Lubbock, TexasAges 18 years+ - NCT07240792Recruiting
CBT for rural high school students with stress or mood issues
This study provides free cognitive-behavioral therapy (CBT) sessions led by college students to help rural high school students manage symptoms of depression, anxiety, or stress. It aims to see if this type of talk therapy can improve emotional well-being.
Hershey, PennsylvaniaAges 13–18 - NCT07243132Recruiting
Long-term survivors in metastatic lung cancer study
This study looks at people who have lived more than three years with advanced lung cancer (non-small cell or small cell) that has spread. The goal is to better understand why some people do well for a long time and how to help more patients.
Aix-en-ProvenceAges 18 years+ - NCT07250061Recruiting
Self-help PTSD program for women veterans
This study tests a self-guided program to help women veterans with PTSD. You would work through coping skills on your own, with support from a group of other women veterans.
Boston, MassachusettsAges 18 years+ - NCT07682064Recruiting
Group therapy for emotional disorders in adults
This trial tests a group therapy program for adults with emotional disorders like depression or anxiety. It is designed to help you manage difficult emotions and improve your well-being.
Logroño, La RiojaAges 18–65 - NCT07224165Recruiting
Digital support for teens who self-injure
This study tests a digital program (like a smartphone app) to help teens who have been hurting themselves on purpose. The goal is to see if using the app can reduce self-injury and help you feel better.
Chicago, IllinoisAges 14–18 - NCT07272252Recruiting
Nursing support to reduce anxiety after planned C-section
This study tests a special kind of nursing care (narrative nursing) to see if it helps mothers feel less anxious and more confident about breastfeeding after a planned, full-term cesarean section. If you are having a scheduled C-section with a healthy pregnancy and baby, you may be able to join.
Nanchong, SichuanAges 18–50 - NCT07278466Recruiting
App support study for depression and anxiety
This study tests two ways of providing support for a mental health app to help people with depression or anxiety. The goal is to see which support method works best to improve symptoms.
Madison, WisconsinAges 18–65 - NCT07280416Recruiting
Sleep changes in first year after cancer diagnosis
This study follows people who are newly diagnosed with cancer to see how their sleep changes during the first year. It looks at whether treatments like chemo or immunotherapy affect insomnia.
Le Puy-en-VelayAges 18–80 - NCT07280481Recruiting
Mindfulness for emotional distress
This trial tests a weekly mindfulness program to help people with anxiety or depression. It aims to see if learning mindfulness can improve your emotional health.
BeijingAges 18 years+ - NCT07290153Recruiting
Psychological health and immunotherapy for TNBC
This study looks at how psychological factors and the immune system affect treatment response in women with triple-negative breast cancer. Researchers will use questionnaires and biological samples to understand these links.
Shanghai, Please SelectAges 18–70 - NCT07292610Recruiting
Nut study for young university students
This trial tests whether eating nuts regularly can improve mental health in young adults. If you are a university student aged 18-25, you may be able to join.
Cuenca, CuencaAges 18–24 - NCT07295652Recruiting
Understanding thinking problems in brain disorders
This study looks at how psychiatric and neurological conditions affect thinking and memory skills. By comparing patients with healthy volunteers, researchers hope to better understand these cognitive problems and find new ways to help.
ParisAges 18 years+ - NCT07296939Recruiting
Youth emotional and behavioral treatment study
This study tests a treatment program for children aged 4 to 17 who have anxiety, mood problems, or difficulty managing emotions and behavior. It aims to help youth and their parents learn skills to improve emotional and behavioral health.
Tallahassee, FloridaAges 4–17
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Common questions
- Are there clinical trials for depression?
- Yes. Clin2 currently lists 1,509 recruiting depression studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a depression trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a depression trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.