Clinical trials
Diabetes Mellitus clinical trials
Below are recruiting diabetes mellitus clinical trials, each written for real people, not researchers. We’re tracking 887 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06884059RecruitingPhase 1
Time-restricted eating for people with early kidney signs
This study tests whether eating only during a certain window each day helps people with type 2 diabetes and small amounts of protein in their urine (a sign of early kidney stress) improve their health. You'll use a smartphone app to log your meals and follow a daily eating schedule.
La Jolla, CaliforniaAges 18–75 - NCT04014413Recruiting
Fecal transplant for gut and immune-related conditions
This trial studies whether fecal microbiota transplantation (FMT)—a medical procedure using stool from a screened donor to restore gut bacteria—can improve safety and outcomes for people with certain bowel, immune, and metabolic conditions. It may help if your symptoms are thought to be related to an unhealthy gut microbiome, though eligibility is broad and depends on specific safety factors.
Hong Kong, ShatinAges Any age - NCT04055428RecruitingPhase 2
Testing a hormone supplement to improve heart and metabolic health
This study tests whether adding a natriuretic peptide medicine improves heart health and metabolism in Black adults. It may help with blood pressure and related health markers, but you must meet specific health and safety criteria.
Birmingham, AlabamaAges 18 years+ - NCT04185844Recruiting
Chronic kidney health study for Native American adults
This study follows Native American adults with kidney function changes (either moderately reduced kidney filtration or early urine protein). It aims to better understand kidney disease over time and what factors predict progress, which may help improve care for people like you.
Phoenix, ArizonaAges 21–80 - NCT04201600Recruiting
Study how blood sugar swings affect thinking in prediabetes
This study looks at how “blood sugar variability” (how much glucose levels bounce around) may affect thinking and memory in people with prediabetes. You may be eligible if you’re older and don’t already have diabetes or conditions that can strongly affect the brain or blood vessels.
Baltimore, MarylandAges 50 years+ - NCT04501406RecruitingPhase 2
Low-dose pioglitazone for fatty liver disease in people with type 2 diabetes
This Phase 2 study tests whether low-dose pioglitazone can improve NASH, a type of fatty liver disease, in adults who also have type 2 diabetes. You may be able to join if your diabetes medicines and lab tests meet specific safety and stability requirements.
Gainesville, FloridaAges 21–75 - NCT04529889Recruiting
Study of gestational diabetes during pregnancy and child outcomes
This study follows pregnant people with gestational diabetes to see how it affects mothers and babies over time. The team may use this information to better understand risks and care for both you and your child.
Guangzhou, GuangdongAges Any age - NCT04547348RecruitingPhase 3
Denosumab for healing an acute Charcot foot in diabetes
This Phase 3 trial tests whether denosumab can improve healing and outcomes for people with an acute Charcot foot caused by diabetes-related nerve problems. You may be able to join if your Charcot foot is recently diagnosed and you meet specific safety and lab requirements.
AalborgAges 18–80 - NCT04634591Recruiting
Weight-loss surgery study for people with severe obesity
This trial studies bariatric (weight-loss) surgery and how well it helps people reach and keep a healthier weight. You may qualify if you have severe obesity and have not been able to maintain weight loss with other attempts, and if you can safely follow the study plan.
Bialystok, Podlaskie VoivodeshipAges 18 years+ - NCT04943861Recruiting
Study on HIV and food insecurity support
This study is looking at food insecurity in adults living with HIV. It may help improve understanding of the barriers to healthy living and guide better support for people affected by HIV.
Winston-Salem, North CarolinaAges 18 years+ - NCT05009433Recruiting
Exercise plans in pregnancy and afterward for mom and baby health
This study compares two types of exercise—short, intense intervals versus moderate steady activity—during pregnancy and looks at effects on mothers and children. It also checks how participants do on health, fitness, and well-being tests before, during, and after pregnancy.
Gdansk, Pomeranian VoivodeshipAges 18–45 - NCT05117424Recruiting
Study of metabolism and plaque changes in heart disease
This trial looks at how treating or managing conditions like diabetes, prediabetes, obesity, kidney disease, or high cholesterol affects artery plaque over time. It may help researchers find ways to slow plaque buildup and related heart risks.
ShanghaiAges 18–80 - NCT05156736Recruiting
Study of early heart artery disease in South Asians
This study looks at early buildup of plaque in heart arteries in young adults from Pakistan. It may help doctors understand why this happens earlier and guide better prevention and screening.
Karachi, SindhAges 35–65 - NCT05164263RecruitingPhase 4
Testing empagliflozin for adults with type 2 diabetes on tablets
This study looks at how well and how safely empagliflozin works in real-world care for adults with type 2 diabetes who are not controlled on current pill treatment. Some participants take it with metformin, and the study helps confirm what to expect in everyday patients.
Kabul, AfghanistanAges 18–65 - NCT05165706Recruiting
Study of how obesity affects insulin resistance over time
This study follows adults over time to understand how weight and body chemistry relate to insulin resistance. It may help researchers learn why insulin resistance happens and what could prevent or improve it.
Stanford, CaliforniaAges 35–65 - NCT05174052RecruitingPhase 3
Dapagliflozin for heart rhythm problems in diabetes
This trial studies dapagliflozin, a diabetes medicine, to see if it can help people with paroxysmal atrial fibrillation (irregular heart rhythm). If you have both diabetes and this type of AF, the study may offer a chance to improve your heart rhythm and outcomes.
Oklahoma City, OklahomaAges 18–85 - NCT05211375RecruitingPhase 3
Compare two weight-loss surgeries for type 2 diabetes control
This Phase 3 trial compares sleeve gastrectomy versus a different bypass-style operation to improve blood sugar in adults with type 2 diabetes. It may help some people lower blood sugar and diabetes medication needs, but you must meet specific safety and health criteria.
Seongnam-siAges 18 years+ - NCT05248412Recruiting
Study how COVID-19 long-term effects impact chronic diseases
This research looks at how the COVID-19 pandemic has affected the health and healthcare of adults with long-term conditions like diabetes, high blood pressure, heart disease, cancer, kidney disease, or chronic lung disease. It compares people who may have been affected by the pandemic and looks at their health and access to care over time.
Hong Kong, Hong KongAges 18 years+ - NCT05275608Recruiting
Low-carb diet effects in people with metabolic syndrome
This trial studies whether a very low-calorie, low-carb diet (VLCKD) can improve metabolic health in adults with metabolic syndrome, fatty liver, and type 2 diabetes. It may help lower blood sugar and improve related health markers if you fit their specific diabetes and liver/kidney criteria.
Novara, ItalyAges 25–65 - NCT05370014Recruiting
Study for COVID survivors and their unpaid carepartners in South Carolina
This study looks at how to improve health and support for African American adults who had COVID-19 severe enough to need urgent care or hospitalization, along with the unpaid carepartner who helps them at home. It may be helpful if you and your carepartner live in a medically underserved or rural area and share daily support needs.
Columbia, South CarolinaAges 18 years+ - NCT05377268Recruiting
Ultrasound scan to find insulin skin lumps and improve sugar control
This study uses an ultrasound scan to find fatty lumps on the skin caused by insulin injections (called lipohypertrophy). It aims to help you improve blood sugar control by identifying and addressing where insulin is being injected.
Vancouver, British ColumbiaAges 19–80 - NCT05404061Recruiting
Study for people who don’t lose weight after bariatric surgery
This study looks at people who have had bariatric surgery but still struggle to lose weight (or lose it poorly). It aims to better understand how to help “poor responders” and what might be interfering with weight-loss results.
LondonAges 18–70 - NCT05407207Recruiting
Electrical stimulation during dialysis to improve walking and balance
This study tests whether a special electrical stimulation treatment to the soles of the feet during dialysis can improve balance and walking in people with diabetes who have nerve damage in the feet. If it works, it may help reduce fall risk and improve mobility.
Houston, TexasAges 40 years+ - NCT05476627Recruiting
Study risk factors for kidney disease from metabolic conditions
This study looks at risk factors and body “omics” information (like blood/tissue patterns) to better understand chronic kidney disease caused by metabolic diseases. It may help researchers find better ways to predict or manage kidney problems in people with these conditions.
Beijing, Beijing MunicipalityAges 18–80
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Common questions
- Are there clinical trials for diabetes mellitus?
- Yes. Clin2 currently lists 887 recruiting diabetes mellitus studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a diabetes mellitus trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a diabetes mellitus trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.