Clinical trials
Diabetes clinical trials
Below are recruiting diabetes clinical trials, each written for real people, not researchers. We’re tracking 2,132 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT05478707RecruitingPhase 2
Treating small blood vessel problems in type 1 diabetes
This study tests whether two different treatment strategies can improve the function of the tiny blood vessels in people with type 1 diabetes. It aims to find a way to prevent or reduce diabetes-related complications.
Orlando, FloridaAges 18–40 - NCT05482789RecruitingPhase 4
Exenatide study in pregnancy-related diabetes without medicines
This trial studies how exenatide affects blood sugar in pregnant people with gestational diabetes who do not need medication yet. The goal is to understand how the medicine works in the body during pregnancy, which may help improve future treatment decisions.
Pittsburgh, PennsylvaniaAges 18–50 - NCT05414409RecruitingPhase 2
Gut microbiome study in young people with type 1 diabetes
This Phase 2 study looks at the gut microbiome (the bacteria in your intestines) in youth with type 1 diabetes, and how metformin may work differently through the gut. It may help researchers understand mechanisms and future treatment options.
Indianapolis, IndianaAges 11–18 - NCT05420051Recruiting
Program to boost happiness and emotional well-being in type 2 diabetes
This trial tests whether a support program using messages and coaching can improve emotional well-being and happiness for people with type 2 diabetes. It may also encourage healthier activity, especially if you’re currently not very active.
Boston, MassachusettsAges 18 years+ - NCT05415878Recruiting
Comparing removable boot designs for diabetic foot ulcers
This study compares different removable cast walkers (special boots) to see which is easier for people with diabetic foot ulcers to use. If you join, you'll try one of these boots and share your experience, which may help heal your ulcer while keeping you mobile.
North Chicago, IllinoisAges 18 years+ - NCT05398783Recruiting
Study of how metabolism and body composition change over time
This natural history study follows people to understand how metabolism and body composition vary in health and disease. It may help researchers better measure metabolic changes and understand who is at risk as health and treatments change.
Bethesda, MarylandAges 2–99 - NCT05369052RecruitingPhase 3
New antibiotic for moderate or severe diabetic foot infections
This Phase 3 trial tests a new medicine (contezolid acefosamil, and contezolid) to treat moderate or severe diabetic foot infections. It compares the new treatment to linezolid to see which works better and is safer for adults.
Corona, CaliforniaAges 18 years+ - NCT05365438RecruitingPhase 4
Atorvastatin plus omega-3 for artery plaque in type 2 diabetes
This trial studies whether a combination of atorvastatin and omega-3 can reduce signs of artery plaque in people with type 2 diabetes and “mixed” cholesterol problems. It’s focused on people who don’t have symptoms from plaque yet.
Seongnam-si, Gyeonggi-doAges 20–80 - NCT05365425RecruitingPhase 4
Choline fenofibrate to reduce plaque in type 2 diabetes
This trial studies whether choline fenofibrate can improve blood vessel plaque (carotid artery plaque) in people with type 2 diabetes and mixed cholesterol problems. It aims to see if the medicine can make carotid plaque thinner or otherwise healthier while keeping safety in mind.
Seongnam-si, Gyeonggi-doAges 20 years+ - NCT05390892RecruitingPhase 4
Preventing kidney and heart damage in type 2 diabetes
This study tests whether diabetes medicines can help prevent worsening heart and kidney problems in people with type 2 diabetes. You’ll be assigned by chance to one of these medicine types, and your other care will be adjusted for safety.
Huntsville, AlabamaAges 40–80 - NCT05348863Recruiting
Digital coaching for self-care in gestational diabetes
This trial studies a digital (phone or online) platform meant to help people manage gestational diabetes during pregnancy. If you qualify, you may be asked to use the tool to support daily self-care and decision-making.
LinköpingAges 18–50 - NCT05317455RecruitingEarly Phase 1
Studying brain sugar changes in adults with risky low blood sugar
This early-stage study looks at how the brain uses sugar in people with type 1 diabetes who have had severe or hard-to-notice low blood sugar. It may help researchers understand the brain effects of low blood sugar and guide safer care.
New Haven, ConnecticutAges 18–55 - NCT05322213RecruitingPhase 1
THC study for blood sugar control in type 2 diabetes
This early-phase study tests how THC (the main cannabis ingredient) affects blood sugar levels in people with type 2 diabetes. It may help researchers understand whether THC changes glucose control and what risks come with it.
La Jolla, CaliforniaAges 21–70 - NCT05305794RecruitingPhase 3
Weekly shot to improve blood sugar control in double diabetes
This trial tests a weekly injection (similar to Ozempic) for people with type 1 diabetes who also have features of type 2 diabetes (often called 'double diabetes'). The goal is to see if this extra treatment can help lower blood sugar and improve overall diabetes management.
DijonAges 18 years+ - NCT05279729Recruiting
Mobile app coaching for people with diabetes
This study tests whether using a smartphone app can help people with type 2 diabetes manage their health. It focuses especially on low-income Hispanic/Latinx adults who regularly check blood sugar.
San Diego, CaliforniaAges 18–64 - NCT05307731RecruitingPhase 4
Fingolimod for adults with type 2 diabetes
This trial studies whether fingolimod can improve diabetes in adults with type 2 diabetes who are not yet on many medications. It will mainly check whether the drug is safe and whether it can help control blood sugar over time.
ShenyangAges 18–70 - NCT05269589Recruiting
Home heat therapy for people with type 2 diabetes
This trial tests whether using heat therapy at home can improve health in adults with type 2 diabetes. It may help people who already have stable diabetes treatment, but it is not for everyone, especially if certain heart, nerve, or vision problems are present.
Montreal, QuebecAges 45–75 - NCT05268250Recruiting
Program to help school families cope with type 1 diabetes stress
This trial tests a structured program and screening approach to help school-age children and their families who are feeling significant stress about diabetes. It may help by identifying distress early and offering targeted support alongside an intensive diabetes care plan.
Jacksonville, FloridaAges 8–65 - NCT05267990Enrolling by invitation
CT calcium scan to prevent heart problems in diabetes
This trial studies whether using a heart CT “calcium score” to guide prevention can lower the chance of major heart disease in people with type 2 diabetes who have other heart risk factors. It may help by targeting prevention more personally, based on your calcium score.
YilanAges 40 years+ - NCT05296447Enrolling by invitationPhase 2
Long-term safety study for diabetic retinopathy gene therapy
This study follows people who already received an injection of RGX-314 (an experimental gene therapy) in a previous clinical trial for diabetic retinopathy, with or without swelling in the macula. It checks the long-term safety and how the treatment works over time.
Phoenix, ArizonaAges Any age - NCT02841553Recruiting
Online registry for Wolfram syndrome worldwide
This study builds an international online registry to learn how Wolfram syndrome (and related WFS1 conditions) changes over time. It may help researchers understand the disease course and improve future care by collecting health and family history data.
St Louis, MissouriAges birth+ - NCT03821636Recruiting
Compare gastric bypass limb lengths for type 2 diabetes remission
This study looks at whether a gastric bypass surgery with a longer intestine segment or a longer bile drainage segment leads to better type 2 diabetes remission in people with severe obesity. It may help doctors choose the most effective surgical approach and follow-up plan for diabetes improvement.
AmiensAges 18–60 - NCT04583800Recruiting
Tracking heart failure risk and memory change in diabetes
This study follows adults with type 2 diabetes to see who may develop heart problems and who may have memory or thinking changes over time. It may help doctors better predict risk and plan earlier support.
LilleAges 18 years+ - NCT05139784Recruiting
Study of immune changes in people with type 1 diabetes and other diabetes
This study looks at immune (defense system) and blood-sugar changes in people with type 1 diabetes, and in some other diabetes or autoimmune hormone conditions. It includes people who will have a specific abdominal surgery so doctors can safely study lymph node tissue.
Bobigny, Île-de-France RegionAges 1 year+
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Common questions
- Are there clinical trials for diabetes?
- Yes. Clin2 currently lists 2,132 recruiting diabetes studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a diabetes trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a diabetes trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.