Clinical trials
Disease clinical trials
Below are recruiting disease clinical trials, each written for real people, not researchers. We’re tracking 9,353 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT02471378Recruiting
Testing a malaria vaccine in pregnant people with malaria
This study looks at lab tests for malaria vaccine candidates in pregnant women who currently have malaria. It may help researchers understand which vaccine approaches are safest and most promising for pregnancy.
BamakoAges 15–25 - NCT02564692Enrolling by invitation
APOE gene testing registry to find Alzheimer’s prevention studies
This program enrolls people to get a gene test (APOE) so researchers can match you to Alzheimer’s prevention studies in the future. If you qualify, you do the test but you would not receive your gene test results.
Phoenix, ArizonaAges 50–90 - NCT02306200Recruiting
A study to improve heart and aorta health
This trial looks at ways to improve cardiovascular (heart and blood vessel) health, especially conditions that affect the aorta, such as aneurysms, or vascular problems that may run in families. If you have an aortic-related or other cardiovascular diagnosis (or you’re a healthy comparison participant), you may be invited to take part in this health-improvement program.
Ann Arbor, MichiganAges Any age - NCT02553525Enrolling by invitation
Testing different stimulation patterns in Parkinson’s, tremor, and MS
This study tests whether changing the “stimulation pattern” in a deep brain stimulator can improve how well symptoms are controlled. If you are already getting (or replacing) a deep brain stimulator, this may help fine-tune the settings for you.
Gainesville, FloridaAges 21–80 - NCT02542683Recruiting
Physical activity program to support children’s brain development
This study looks at whether a structured physical activity program can support thinking and brain development in children around age 2–5. Your child may be eligible if they are having certain surgeries or fit a matched “control” group and do not have specific neurologic or heart-related issues.
New York, New YorkAges 2.5 years–6 years - NCT02414178Enrolling by invitation
Tau PET brain scan for inherited Alzheimer’s disease
This study uses a special brain scan to measure “tau” buildup in people with an inherited form of Alzheimer’s. It may help researchers better understand disease changes and evaluate whether the scan can track them over time.
St Louis, MissouriAges 18 years+ - NCT02573753Recruiting
Study how sleep affects gut bacteria and health
This study looks at how different sleep patterns change the microorganisms in your gut (gut bacteria) and what that may mean for health. It’s mainly for people who can take part in other approved research studies at the same time.
Rochester, MinnesotaAges 18 years+ - NCT02202681Enrolling by invitation
Swallowable capsule scans the duodenum with special imaging
This study tests whether a swallowable imaging capsule can safely look at the duodenum (the first part of the small intestine). It may help researchers better understand gut lining changes, such as those seen in celiac disease.
Boston, MassachusettsAges 16 years+ - NCT02363595Recruiting
Genetic clues for how small thyroid cancers may grow
This study looks at gene changes to predict whether a small papillary thyroid cancer found on biopsy is likely to stay stable or grow over time. It may help doctors choose who can safely stay on watchful waiting.
New York, New YorkAges 18 years+ - NCT02582021Recruiting
Study of treatments and imaging in women with angina or HFpEF
This trial studies how heart disease affects the heart using heart imaging, and looks at people with chest pain/angina or heart failure with preserved pumping strength (HFpEF). It may help doctors better understand what’s driving symptoms and how best to evaluate these conditions.
Los Angeles, CaliforniaAges 18 years+ - NCT02393703Recruiting
Testing blood signals from tiny cell packets in pancreatic surgery
This study looks at how tiny particles in blood (“exosomes”) carry signals between cells in people having pancreatic surgery. The goal is to understand these signals in different pancreatic conditions and treatment situations, which may help future care.
New York, New YorkAges 18 years+ - NCT02422641RecruitingPhase 2
High-dose methotrexate for breast cancer in the brain lining
This Phase 2 trial tests whether giving high-dose methotrexate into the bloodstream can help treat breast cancer that has spread to the thin lining covering the brain and spinal cord. It may help reduce cancer in the leptomeningeal (brain-lining) area and control symptoms.
Baltimore, MarylandAges 18 years+ - NCT02604563Recruiting
Aging, blood changes, and health in older adults
This study examines why some older adults develop changes in their blood cells that may affect their health. Researchers will look for links between these blood changes, aging, and common health problems in older people.
St Louis, MissouriAges 50 years+ - NCT02669797Enrolling by invitation
Family-based program to help families eat dinner together
This study offers an intervention focused on family dinners to help children improve their eating habits. It targets children who eat family dinners rarely and have a higher weight range, to see if the program can help improve health over time.
Aurora, ColoradoAges 5–10 - NCT02669602Enrolling by invitation
Spanish university graduates’ health follow-up study
This is an observational study that follows Spanish university graduates over time to learn how health changes. It may help researchers understand risk factors and what lifestyle or health patterns are linked to better or worse outcomes.
Pamplona, NavarreAges Any age - NCT02526095Recruiting
Esophagus or stomach cancer registry for treatment and outcomes
This trial is a cancer data and blood-sample registry. It collects information from people newly diagnosed with esophagus or stomach (or the stomach–esophagus junction) cancer to help researchers understand treatment patterns and outcomes.
AmiensAges 18–90 - NCT02497521Recruiting
Registry for adults with ADPKD starting tolvaptan
This registry study collects information about adults with autosomal dominant polycystic kidney disease (ADPKD) who are starting or already taking tolvaptan. It may help researchers understand how tolvaptan is used in real life and what outcomes look like over time.
Müllheim, Baden-WurttembergAges 18 years+ - NCT02240862Recruiting
Carotid artery disease registry for symptom and risk groups
This is a registry that enrolls adults with narrowed carotid arteries (with symptoms or no symptoms). It collects health and treatment information to better understand which patients benefit from procedures and when.
Baltimore, MarylandAges 18–80 - NCT02402426Enrolling by invitation
Online brain health registry for adults
This study is building an online registry where adults can share information to help researchers find people for future brain research. Joining may help future studies get the people they need.
San Francisco, CaliforniaAges 18 years+ - NCT02541435Recruiting
Breast cancer radiotherapy side effects study
This study looks at heart and blood-vessel side effects after modern radiation treatment for breast cancer, both soon after and years later. It may help doctors understand who is at risk and how to monitor heart health over time.
ÅlesundAges 30–70 - NCT01772602Recruiting
Join a national ALS patient registry in the U.S.
This study is a national registry that collects information from people with amyotrophic lateral sclerosis (ALS) to better understand the disease. Joining may help researchers learn about patterns of symptoms and care over time.
Atlanta, GeorgiaAges 18 years+ - NCT01927783Recruiting
Community weight loss program for people in Washington area
This study tests a community-based behavioral weight loss program. It may help participants learn practical habits for healthier weight by working with people in local faith communities.
Bethesda, MarylandAges 19–85 - NCT01306084Recruiting
Study of viral infections in healthy and immune-compromised people
This trial studies how viruses affect the body, and how the immune system responds, in both healthy people and people with weakened immunity. It may include people who currently have a suspected or recent viral infection, close contacts, people around the time of a viral vaccine, and healthy adults used for comparison.
Bethesda, MarylandAges 6 months–120 years - NCT01306019RecruitingPhase 1/Phase 2
Gene therapy for children with severe immune deficiency (XSCID)
This trial tests a one-time gene therapy approach to help children with X-linked SCID (a serious inherited immune disorder) make better immune cells. It’s for people who don’t have a fully matched sibling donor and need long-term follow-up after treatment.
Bethesda, MarylandAges 2–50
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Common questions
- Are there clinical trials for disease?
- Yes. Clin2 currently lists 9,353 recruiting disease studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a disease trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a disease trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.