Clinical trials
Down Syndrome clinical trials
Below are recruiting down syndrome clinical trials, each written for real people, not researchers. We’re tracking 3,055 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06674707Recruiting
Agility training with foot exercises for kneecap pain
This trial tests whether adding foot exercises to agility training can better relieve long-lasting knee pain (patellofemoral pain syndrome) in adults ages 20 to 40. Eligible participants will have had pain behind the kneecap for over 6 months.
Lahore, Punjab ProvinceAges 20–40 - NCT07668011Recruiting
Shockwave therapy for iliotibial band syndrome
This study tests whether a type of sound wave therapy (radial shockwave) can help relieve pain from iliotibial band syndrome (ITBS) in active adults. If you have outer knee pain when running and have been diagnosed with ITBS in the last month, you may be able to join.
Giza, Giza GovernorateAges 18–45 - NCT07668908Enrolling by invitation
Virtual reality exercise program for Down syndrome
This trial tests whether an immersive virtual reality exercise program can help people with Down syndrome improve their fitness and health. Participants will do high-intensity workouts in a virtual reality environment.
Pontevedra, PontevedraAges 16–50 - NCT07668206Recruiting
Talking therapy for thoracic outlet syndrome pain
This study tests if talking with a counselor (motivational interviewing) can help people with long-term pain from thoracic outlet syndrome feel better. It is for adults who have not had surgery recently.
AnkaraAges 18–65 - NCT06673953Recruiting
Breathing training for heart surgery recovery with neck posture problems
This trial tests whether a breathing exercise device can improve heart and lung function in men who had heart bypass surgery at least 3 months ago and also have neck pain from poor posture. It may help you breathe better and feel stronger after surgery.
Giza, Giza GovernorateAges 45–55 - NCT06073860Recruiting
Safety study of Luspatercept for MDS or thalassemia in Korea
This study is checking the safety of a drug called Luspatercept (brand name Reblozyl) for people in Korea who have myelodysplastic syndrome (a blood disorder) or beta-thalassemia (a type of inherited anemia). It is designed to monitor how safe the drug is when used as prescribed by your doctor.
SeoulAges 19 years+ - NCT07655102Recruiting
Brugada Syndrome and Anesthesia: A Registry Study
This study is collecting information from people with Brugada syndrome who are having anesthesia or sedation for any procedure. The goal is to learn more about how these medications affect people with Brugada syndrome, so doctors can provide safer care in the future.
Barcelona, BarcelonaAges Any age - NCT07660913Recruiting
Vibrating therapy for carpal tunnel syndrome
This study tests whether a gentle vibrating therapy (matrix rhythm therapy) can help relieve pain, tingling, and numbness from carpal tunnel syndrome. Participants will receive the therapy, and researchers will track if it improves hand function without surgery or drugs.
IzmirAges 18–60 - NCT07657312RecruitingPhase 2
Infliximab to prevent side effects during myeloma treatment
This trial tests if infliximab, a drug that calms the immune system, can prevent cytokine release syndrome (a serious side effect) when patients receive teclistamab or talquetamab for multiple myeloma that has returned or not responded to treatment.
Columbus, OhioAges 18 years+ - NCT07655492Recruiting
Tailored brain training for Sturge-Weber syndrome
This study tests a personalized memory and thinking skills program designed for people with Sturge-Weber syndrome. It aims to see if this program can help improve daily life and brain function.
Roma, RomaAges 2 years+ - NCT06677866Recruiting
Group therapy for teens with Fragile X or autism
This trial tests if group cognitive behavioral therapy (CBT) can help teens with Fragile X syndrome or autism spectrum disorder improve social and emotional skills. It looks at how teens with these conditions respond to a structured group program.
RomeAges 13–19 - NCT07653789Recruiting
Hand exercises for carpal tunnel in pregnancy
This study compares three types of hand and wrist exercises to see which works best for mild to moderate carpal tunnel syndrome during pregnancy. It may help reduce pain and improve hand function.
Islamabad, ICTAges 18–45 - NCT07646899Recruiting
Unstable Loads and Shoulder Movement in Overhead Athletes
This study investigates how using unstable equipment (like a wobbly barbell) affects shoulder blade movement and muscle use during overhead pressing in athletes with shoulder impingement pain. The goal is to understand whether unstable loads might help improve shoulder mechanics and reduce pain in overhead athletes.
TaipeiAges 18–40 - NCT07652879RecruitingPhase 2
KCD drug combination for newly diagnosed POEMS syndrome
This trial tests a combination of three drugs (carfilzomib, cyclophosphamide, and dexamethasone) for people newly diagnosed with POEMS syndrome. It aims to see how well this treatment helps control the disease and its symptoms.
ShanghaiAges 18–75 - NCT06686290Recruiting
Stretching exercises for levator scapulae pain
This trial compares two stretching techniques to relieve chronic neck and shoulder blade pain caused by tight levator scapulae muscles. It may help you if you have had this pain for at least 3 months and have trouble turning or tilting your head.
Daska Kalan, Punjab ProvinceAges 24–59 - NCT06687018Recruiting
Comparing two hand therapies for carpal tunnel relief
This study tests two types of gentle hand and wrist movements (mobilizations) to see which better relieves pain, tingling, and numbness in carpal tunnel syndrome. It may help you if you have these symptoms and are otherwise healthy.
Lahore, Punjab ProvinceAges 20–45 - NCT06690801Recruiting
Nitric oxide breathing gas for children with lung failure
This trial tests whether adding a breathing gas called nitric oxide to standard care helps children with severe lung failure (ARDS) recover faster. It is for children on a breathing machine who still have low oxygen levels.
Los Angeles, CaliforniaAges birth–21 years - NCT07638137Recruiting
Advanced Heart Catheter Testing for Stent Patients With Chest Pain
This study tests a detailed diagnostic procedure during heart catheterization for patients who previously had stents placed and now have chest pain or signs of heart stress. The goal is to better understand blood flow in treated arteries to guide treatment decisions.
Leganés, MadridAges 18 years+ - NCT07642232Recruiting
Somatic Movement vs Core Strengthening for Premenstrual Syndrome
This study compares two exercise approaches—somatic movement therapy (mindful, body-awareness exercises) and core strengthening—to see which better reduces premenstrual syndrome symptoms like mood changes and physical discomfort. You'd participate in one type of exercise program over several weeks.
Lahore, Punjab ProvinceAges 18–35 - NCT07645014Recruiting
Physical Therapy for PCOS Pain and Irregular Periods
This study compares two hands-on physical therapy techniques to see if they help reduce period pain and improve symptoms in women with PCOS (a hormone condition affecting the ovaries). You'll receive either neurodynamic stretching or myofascial release therapy to see which works better.
Lahore, Punjab ProvinceAges 18–35 - NCT07640503Enrolling by invitationPhase 2
Lamivudine Treatment Study for Rett Syndrome
This study tests whether lamivudine, a medication originally used for HIV, might help improve symptoms in people with Rett syndrome. Researchers will monitor how safe and effective the treatment is over time.
Fortaleza, CearáAges 2 years+ - NCT07642089Recruiting
Stretching and strength training for restless legs in pregnancy
This study tests whether gentle stretching and strength exercises can help pregnant women with restless leg syndrome—a condition that causes uncomfortable sensations in the legs and disrupts sleep. The goal is to see if these exercises reduce symptoms and improve sleep quality during pregnancy.
Lahore, Punjab ProvinceAges 18–35 - NCT07646314Recruiting
Physical therapy techniques for piriformis syndrome pain
This study compares two hands-on physical therapy methods to reduce pain from piriformis syndrome, a condition where a muscle in the buttock area pinches a nerve. You'll receive treatment and be asked which technique works better for your pain and movement.
Lahore, Punjab ProvinceAges 25–40 - NCT07640126Recruiting
Acupuncture for cold-sensitive neck pain
This trial tests whether a specific type of acupuncture (three-needle Dazhui plus electroacupuncture) can reduce pain and improve function in people with neck pain caused by cervical spondylosis, especially when the pain is worse in cold weather. It combines a modern diagnosis with traditional Chinese medicine ideas to see if this approach helps more than standard care.
Ho Chi Minh CityAges 3 weeks+
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Common questions
- Are there clinical trials for down syndrome?
- Yes. Clin2 currently lists 3,055 recruiting down syndrome studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a down syndrome trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a down syndrome trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.