Clinical trials
Down Syndrome clinical trials
Below are recruiting down syndrome clinical trials, each written for real people, not researchers. We’re tracking 3,055 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07636811RecruitingPhase 2
Mivelsiran for Early Alzheimer's in Down Syndrome
This trial tests a new drug called mivelsiran designed to slow early-stage Alzheimer's disease in adults with Down syndrome. The drug works by targeting amyloid, a protein that builds up in the brain and causes cognitive decline.
Maitland, FloridaAges 40–55 - NCT07629505Recruiting
CoQ10 supplement for chronic pelvic pain in men
This trial tests whether a CoQ10 supplement (Ralivia) can reduce chronic pelvic or perineal pain lasting at least 3 months. The study aims to see if this supplement helps relieve symptoms when other treatments haven't fully worked.
ThessalonikiAges 18–50 - NCT07630207Recruiting
Blood vessel health in adults with Down syndrome
This study looks at how blood vessels work in adults with Down syndrome compared to those without Down syndrome. It aims to understand heart health better and may help improve future care.
Las Vegas, NevadaAges 18–35 - NCT07636876Enrolling by invitation
Italian MS and Related Disorders Patient Registry
This is a registry study that collects health information from people with multiple sclerosis and related conditions. By joining, you help researchers better understand these diseases and improve future treatments.
Genova, GenovaAges Any age - NCT07635394Recruiting
Pregabalin for Irritable Bowel Syndrome Relief
This study tests whether pregabalin, a nerve-pain medication, can help reduce irritable bowel syndrome (IBS) symptoms like abdominal pain and irregular bowel habits. Researchers want to see if it's safe and effective for people with mild-to-moderate IBS.
Beijing, Beijing MunicipalityAges 18–70 - NCT07632534Recruiting
Serum Eye Drops for Severe Dry Eye Study
This study tests a new eye drop treatment made from your own blood serum for severe dry eye that hasn't improved with standard treatments. Researchers will analyze proteins in your tears to understand why this treatment works and who benefits most.
Saint-EtienneAges 18 years+ - NCT07633236RecruitingPhase 3
Olanzapine to prevent appetite and weight loss during cancer chemotherapy
This study tests whether olanzapine, a medication that can increase appetite, helps prevent severe appetite loss and muscle wasting in patients with ovarian or stomach cancer who are receiving chemotherapy before surgery. The goal is to help patients maintain nutrition and strength during treatment.
MoscowAges Any age - NCT07621068Recruiting
Hyperbaric Oxygen Therapy for Chronic Fatigue Syndrome
This study tests whether breathing pure oxygen in a pressurized chamber can reduce fatigue and improve symptoms in people with mild-to-moderate chronic fatigue syndrome (ME/CFS). The therapy may help your body recover better by increasing oxygen supply to affected tissues.
ZrifinAges 18 years+ - NCT07628387Recruiting
Exercise Types for Restless Legs in Pregnancy
This study compares two types of exercise—aerobic (heart-pumping) and muscle relaxation—to help pregnant women with restless leg syndrome sleep better and feel less tired. Restless leg syndrome causes uncomfortable sensations in the legs, especially at night, which disrupts sleep during pregnancy.
Lahore, Punjab ProvinceAges 20–40 - NCT07625332RecruitingPhase 2/Phase 3
Galantamine for Metabolic Syndrome in Spinal Cord Injury
This study tests whether a medication called galantamine can help improve metabolic syndrome (a cluster of health conditions including obesity, high blood sugar, and high cholesterol) in people with chronic spinal cord injury. The goal is to see if this treatment can reduce health risks and improve overall wellness.
West Orange, New JerseyAges 21–75 - NCT07625579Recruiting
Collaboration for Down Syndrome Progress Research Study
This research study aims to better understand Down syndrome by collecting health information, family history, and sometimes brain imaging or sleep data from children and adults with Down syndrome and their families. The goal is to advance knowledge that could improve health and development for people with Down syndrome.
Orange, CaliforniaAges Any age - NCT07628413Recruiting
Exercise Methods for Neck and Shoulder Pain
This study compares two types of gentle exercise programs—Egoscue and Feldenkrais—to help people with chronic neck pain and poor posture. Both programs focus on retraining muscles and improving how your body moves, and the study will measure which approach works better.
Lahore, Punjab ProvinceAges 25–45 - NCT06702085Recruiting
Lifestyle changes for older adults with tinnitus and metabolic syndrome
This study tests whether lifestyle changes (like diet and exercise) can help older adults who have both metabolic syndrome and chronic tinnitus (ringing in the ears). It is for people 65 and older with class 1 obesity and long-term ear ringing in both ears.
Dokki, Giza GovernorateAges 65–75 - NCT06703788RecruitingPhase 1/Phase 2
Traditional Chinese Medicine Day Care for Metabolic Syndrome
This trial tests a day care program that combines traditional Chinese medicine with regular care for people with metabolic syndrome. It aims to see if this approach helps improve your health better than standard care alone.
TaoyuanAges 20–75 - NCT06615206Recruiting
First CRISPR RNA therapy for MECP2 duplication syndrome
This trial tests a new CRISPR therapy that edits RNA to treat a rare genetic condition called MECP2 duplication syndrome (MDS). It is for boys aged 2 to 18 who have stable seizures and no other major health problems, with the goal of improving symptoms and safety.
Beijing, Beijing MunicipalityAges 2–18 - NCT07615868RecruitingPhase 1
New blood-thinner study for heart disease patients in China
This study tests a new medication called selatogrel in people with chronic coronary syndrome (long-term heart disease caused by narrowed heart arteries). Researchers want to see how the body processes this drug and whether it helps prevent future heart problems.
BeijingAges 18–85 - NCT07614152RecruitingPhase 3
Growth hormone treatment for girls with Turner syndrome
This study tests whether a new long-acting growth hormone injection helps girls with Turner syndrome grow taller. Turner syndrome is a genetic condition that affects growth, and this trial will see if this treatment is safe and effective.
AnyangAges 2–12 - NCT06481176Recruiting
How exercise affects blood in restless legs syndrome
This trial studies how a single session of exercise changes blood markers in people with restless legs syndrome (RLS) who are not currently being treated. If you have moderate to severe RLS and are not regularly active, this study may help us understand how exercise affects your condition.
Stanford, CaliforniaAges 18 years+ - NCT07611435RecruitingPhase 2
Testing a Safe Control for Alpha-Gal Syndrome Food Challenges
This study helps researchers understand the best way to safely test whether people with alpha-gal syndrome (an allergy to red meat) can tolerate pork. You'll undergo a controlled food challenge with medical supervision and access to emergency medications.
Little Rock, ArkansasAges 12–50 - NCT07605429RecruitingPhase 3
Rugonersen treatment for Angelman syndrome
This study tests a new medicine called rugonersen for people with Angelman syndrome. The medicine is given as an injection into the fluid around the spinal cord and may help improve symptoms by targeting the genetic cause of the condition.
San Diego, CaliforniaAges 1–50 - NCT07604103RecruitingPhase 3
Heart Attack and Pneumonia Recovery Study With Vaccination
This study looks at blood markers (special proteins) in patients who have had both a heart attack and pneumonia, to see how vaccination affects recovery. The goal is to understand whether flu and pneumonia vaccines are safe and helpful for people recovering from these two serious conditions together.
Malang, East JavaAges 18–65 - NCT07605481Recruiting
Managing Dumping Syndrome After Esophageal Cancer Surgery
This study looks at dumping syndrome—a condition where food moves too quickly from your stomach after esophageal cancer surgery—and tests ways to help manage its symptoms like sweating, dizziness, and abdominal discomfort.
Seoul, Gangnam-gu Irwon-Ro 81Ages 18 years+ - NCT07607730Recruiting
Group therapy for emotion control in teens with Prader-Willi syndrome
This study tests a group therapy program designed to help teenagers with Prader-Willi syndrome (a genetic condition) learn better emotional control and regulation skills. Your teen and family would attend weekly group sessions to practice tools for managing emotions like anger or frustration.
Kansas City, MissouriAges 13–17 - NCT07608809Recruiting
Blood Flow Restriction Training vs. Pilates for Shoulder Pain
This study compares two exercise approaches—one using special wraps to limit blood flow during exercise, and standard Pilates—to treat shoulder impingement syndrome (a common condition causing shoulder pain with overhead movements). The goal is to see which method works better at reducing pain and improving shoulder function.
RāshidAges 4 months–1.1 years
Hear when a new Down Syndrome trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.
Common questions
- Are there clinical trials for down syndrome?
- Yes. Clin2 currently lists 3,055 recruiting down syndrome studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a down syndrome trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a down syndrome trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.