Clinical trials
Down Syndrome clinical trials
Below are recruiting down syndrome clinical trials, each written for real people, not researchers. We’re tracking 3,055 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06753487Recruiting
Comparing two gentle therapies for piriformis syndrome in women
This trial tests two hands-on treatments (Facilitated Positional Release and Manual Myofascial Release) to see which works better for women with piriformis syndrome. If you're a woman aged 25–50 with buttock or hip pain for at least 2 months, this study might help you find relief.
Rawalpindi, Punjab ProvinceAges 25–50 - NCT07516496Recruiting
Understanding Body Chemistry in Vascular Ehlers-Danlos Syndrome
This study looks at how bodies with vascular Ehlers-Danlos syndrome (vEDS) process nutrients and energy differently. By comparing people with vEDS to healthy volunteers, researchers hope to find new ways to manage the condition better.
CambridgeAges 18–85 - NCT06705153Recruiting
Laughter yoga for irritable bowel syndrome
This study tests whether laughter yoga can help reduce IBS symptoms like belly pain and bloating, and also improve mood, sleep, and overall quality of life. You would join video calls where you practice special laughing exercises (no jokes needed) and then answer questionnaires.
Erzurum, YakutiyeAges 18–90 - NCT06732713Recruiting
Swiss ball vs. Frenkel exercises for Down syndrome
This trial compares using a Swiss ball versus Frenkel exercises to improve balance and coordination in children with Down syndrome. It may help children who can stand and walk on their own.
Lahore, Punjab ProvinceAges 8–13 - NCT06758050Recruiting
Core exercises for front knee pain
This study tests whether doing core exercises can help reduce knee pain in people with patellofemoral pain syndrome—pain at the front of the knee that comes on gradually. It is meant for young adults with a healthy weight who have had this type of knee pain for more than 3 months.
GizaAges 18–35 - NCT07511751Recruiting
Comparing treatments for myofascial pain syndrome
This trial compares three different treatments to find which works best for long-term back pain caused by myofascial pain syndrome, a condition where tight muscle knots cause pain. It is for people who have not found relief with standard treatments.
Adapazarı, SakaryaAges 18–65 - NCT07511257RecruitingPhase 4
Blood thinners after heart attack with widened arteries
This trial tests two different blood-thinner strategies for people who have had a recent heart attack and also have a widened artery (ectasia) in the heart. The goal is to find the safest and most effective way to prevent another heart attack or clot.
Mexico City, TlalpanAges 18–80 - NCT07512778Recruiting
Heart stent placement guided by ultrasound vs. imaging
This trial compares two ways doctors place heart stents in patients having a heart attack or unstable chest pain. One method uses ultrasound imaging inside the artery (IVUS), and the other uses standard X-ray imaging. The goal is to see which approach leads to better outcomes.
Seoul, Eunpyeong-guAges 19–90 - NCT07499128Enrolling by invitation
Continuous temperature monitoring for cytokine release syndrome
This study tests a wearable device that continuously monitors your body temperature to detect cytokine release syndrome, a possible side effect of certain immunotherapies. The goal is to catch it early so you can get treatment faster.
Bethesda, MarylandAges 18–120 - NCT07505277Recruiting
Testing special foods for people at risk of metabolic syndrome
This trial tests whether foods with antioxidants, prebiotic fibers, and oat beta-glucans can help people who are at risk for metabolic syndrome. It looks at measures like waist size, blood sugar, blood pressure, and cholesterol to see if these foods improve health markers.
Bolzano, BolzanoAges 18–60 - NCT06764511Recruiting
Biosimilar EPO for anemia in low-risk MDS
This trial tests how well a biosimilar version of erythropoietin (a drug that boosts red blood cells) works in people with low-risk myelodysplastic syndrome (MDS) who have anemia. It aims to see if this treatment can safely improve low hemoglobin levels without needing more intensive therapies.
BolognaAges 18 years+ - NCT07501858Recruiting
H. pylori and insulin resistance in metabolic syndrome
This study looks at whether a common stomach infection (H. pylori) affects insulin resistance in people with metabolic syndrome. It uses simple tests like a breath test, stool sample, and blood draw to check if treating the infection could help improve metabolic health.
Novosibirsk, Novosibirsk OblastAges 18–65 - NCT07502573Enrolling by invitation
Comparing two exercise programs for piriformis syndrome
This trial compares a home exercise program with a telerehabilitation program for people with piriformis syndrome. Researchers want to see which approach helps reduce pain and improve function better.
Ankara, KeciorenAges 18–45 - NCT07502612Recruiting
Spinal cord stimulation medication tapering study
This study tests whether lowering pain medication can improve how well spinal cord stimulation works. It is for people who already take certain pain medicines and are scheduled to try a spinal cord stimulator.
WilrijkAges 18 years+ - NCT06748924Recruiting
Chronic coronary syndrome snapshot study
This study looks at how well doctors follow standard guidelines when treating people with chronic coronary syndrome (a type of long-term heart disease). It may help doctors improve care for patients with chest pain, heart disease, or related conditions.
YerevanAges 18 years+ - NCT07496099Recruiting
Comparing two muscle-release therapies for low back pain
This study compares two types of gentle muscle-release techniques—post-isometric relaxation and myofascial release—to see which better relieves low back pain caused by lower cross syndrome, a common muscle imbalance. If you have ongoing back pain and tight hamstrings, this trial may offer a drug-free treatment option.
Karachi, SindhAges 18–45 - NCT07490964Recruiting
Study of PCOS in women with type 1 diabetes
This study looks at the connection between type 1 diabetes and polycystic ovary syndrome (PCOS). It will compare women with both conditions to women with only diabetes and to women without either, to understand how PCOS affects diabetes management.
Madrid, MadridAges 18–45 - NCT07491328Recruiting
Liquid biopsy for nerve disorders linked to cancer
This study uses a blood test (liquid biopsy) to look for cancer-related signals in people with certain nerve disorders caused by the immune system (paraneoplastic neurological syndromes) or in people with tumors that do not affect the nerves. It aims to better understand and detect these conditions.
DüsseldorfAges 18 years+ - NCT07494162Recruiting
Acupuncture for chronic low back pain with muscle knots
This trial tests if acupuncture can help chronic low back pain by looking at changes in muscle metabolism and blood flow. It compares real acupuncture with a sham (fake) procedure to see if there is a true benefit.
Sacramento, CaliforniaAges 18 years+ - NCT05702476Recruiting
Non-invasive 3D scan study for Marfan face features
This study uses a non-invasive 3D scan to better measure facial features in people with Marfan syndrome. It may help researchers describe face differences more accurately, without needles or surgery.
San Donato Milanese, LombardyAges Any age - NCT06641154RecruitingPhase 1/Phase 2
Gene therapy for severe Crigler-Najjar syndrome
This trial tests a gene therapy for children with severe Crigler-Najjar syndrome type I. It aims to reduce the need for daily phototherapy by fixing the faulty gene.
MoscowAges 3 months–10 years - NCT06770218Recruiting
Pelvic taping for stability in Down syndrome
This trial tests whether taping the pelvic area can help children with Down syndrome feel more stable. It may improve their movement and balance.
Lahore, Punjab ProvinceAges 4–10 - NCT07488936Recruiting
How low back pain types affect pain and quality of life after failed back surgery
This study looks at how different types of low back pain affect pain severity and quality of life in people who still have pain after back surgery. It aims to help doctors better understand and treat your pain.
Konya, SelçukluAges 18 years+ - NCT05972837Recruiting
Home electrical stimulation for long-lasting neck muscle pain
This trial studies whether a home-based electrical stimulation device placed on the neck can reduce pain for people with long-lasting neck muscle pain. It may help if your pain has lasted at least 2 months and is moderate to severe.
New Taipei CityAges 20–60
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Common questions
- Are there clinical trials for down syndrome?
- Yes. Clin2 currently lists 3,055 recruiting down syndrome studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a down syndrome trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a down syndrome trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.