Clinical trials
Down Syndrome clinical trials
Below are recruiting down syndrome clinical trials, each written for real people, not researchers. We’re tracking 3,055 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06742073Recruiting
Study of H syndrome and inflammation
This study looks at the link between H syndrome and related health issues, such as inflammation or histiocytosis (a type of immune cell disorder). It helps researchers learn more about how this rare genetic condition affects the body.
Petah TikvaAges Any age - NCT07545759RecruitingPhase 2
Testing brenipatide for IBS with diarrhea symptoms
This study tests whether a new medication called brenipatide can help people with IBS-diarrhea (IBS-D) reduce belly pain and loose stools. IBS-D is a condition where the intestines move too quickly, causing frequent diarrhea and discomfort.
Mesa, ArizonaAges 18–75 - NCT07545772RecruitingPhase 2
Testing Brenipatide for Constipation-Focused IBS
This trial tests a new medicine called brenipatide to see if it can help people with IBS-C (irritable bowel syndrome with constipation). The study focuses on whether the drug reduces belly pain and improves bowel movements in people whose main symptom is hard or infrequent stools.
Mesa, ArizonaAges 18–75 - NCT07546240Recruiting
Radiation therapy for persistent heel pain
This trial tests whether targeted radiation can relieve long-lasting heel pain (plantar fasciitis) that hasn't improved with other treatments. If your heel pain has lasted months and other options haven't worked, radiation might help reduce pain and improve walking.
GliwiceAges 40 years+ - NCT07544914Recruiting
Magnetic Stimulation for Elbow and Wrist Chronic Pain
This study tests whether a non-invasive magnetic therapy applied to the skin can reduce chronic pain from tennis elbow, golfer's elbow, or carpal tunnel syndrome. The treatment uses magnetic pulses to stimulate nerves and may help relieve pain without medication or surgery.
Winnipeg, ManitobaAges 18 years+ - NCT07546539Recruiting
Light Therapy for Chronic Fatigue Syndrome
This study tests whether a special type of light therapy (called photobiomodulation) can reduce severe tiredness in people with chronic fatigue syndrome. The light is applied to the skin and may help boost energy levels and improve daily function.
Larkana, SindhAges 18–60 - NCT07545499Recruiting
Daily rhythms and physical recovery after COVID-19
This study looks at how your body's natural daily rhythms (sleep-wake cycles, energy patterns) affect physical function and daily activities in people recovering from long COVID. Understanding these patterns may help develop better recovery strategies.
Ankara, AltindağAges 18–65 - NCT07547098Recruiting
Heart, Kidney, and Metabolism Health Long-Term Study
This research study tracks patients with heart disease, kidney disease, or metabolic conditions (like diabetes) over time to understand how these conditions connect and affect long-term health. By collecting medical records and health information, researchers aim to predict outcomes and improve care.
Fuzhou, FujianAges 18–80 - NCT06728228Recruiting
Amnioinfusion for fetal kidney failure
This trial is testing whether adding fluid back into the womb (amnioinfusion) can help babies whose kidneys are not working and who have no amniotic fluid early in pregnancy. It may improve the baby's chances of survival and lung development.
Dallas, TexasAges Any age - NCT06747741Recruiting
Stretching vs. physical therapy for restless leg syndrome in seniors
This study compares a special stretching technique (PNF) with standard physical therapy to see which better relieves restless leg syndrome symptoms in people aged 60 and older. It may help reduce the uncomfortable urge to move your legs at night.
IslamabadAges 60 years+ - NCT06124664Recruiting
Study of leg vein drainage in pelvic varicose veins
This study looks at how blood flows from the legs in people with varicose veins in the pelvis. It may help doctors understand the link between pelvic and leg vein problems.
MoskvaAges 18–40 - NCT07538583RecruitingPhase 2/Phase 3
QRX003 Lotion for Netherton Syndrome
This study tests a new lotion (QRX003) designed to treat Netherton Syndrome, a rare genetic skin condition. The lotion is applied to affected skin areas to see if it can reduce symptoms and improve skin health.
Fremont, CaliforniaAges 4 years+ - NCT07540312Recruiting
Compression System for Moderate to Severe Irritable Bowel Syndrome
This trial tests a wearable compression device designed to help people with moderate to severe irritable bowel syndrome (IBS). The device applies variable pressure to the abdomen and may help reduce symptoms like abdominal pain, bloating, and bowel irregularities.
Kissimmee, FloridaAges 18–60 - NCT07541014Recruiting
Home vs. Hospital Heart Rehab After Heart Attack
This study compares two ways to do cardiac rehabilitation (heart exercise and education programs) after a heart attack: one done at home via telehealth (video visits) and one at a clinic. The goal is to see which approach works better and is easier for patients to stick with.
New York, New YorkAges 18 years+ - NCT07537998RecruitingPhase 2/Phase 3
Intestinal Fluid Recycling to Reduce Bowel Problems After Rectal Cancer Surgery
This trial tests a surgical technique that recycles intestinal fluids during rectal cancer surgery to help prevent bowel dysfunction and frequent bowel movements after surgery. If you've had mid-to-low rectal cancer removed and created a temporary opening (stoma), this study may help improve your quality of life.
Guangzhou, GuangdongAges 18–75 - NCT06748248Recruiting
Suspension therapy for mobility and balance in Down syndrome
This trial tests if suspension therapy (a type of physical therapy using supportive straps or harnesses) can help children with Down syndrome improve their ability to move and keep their balance. It may be a helpful option for children who can already stand and walk but want to get stronger and more stable.
Lahore, Punjab ProvinceAges 3–6 - NCT04848870Recruiting
Check dental and gum health in Sjögren’s disease
This study looks at dental and gum (periodontal) health in adults with Sjögren’s syndrome. It may help researchers understand how Sjögren’s affects the mouth and how patients can be supported better.
Ivry-sur-Seine, Île-de-France RegionAges 18 years+ - NCT07531745RecruitingPhase 1/Phase 2
ION337 gene therapy for children with Dravet syndrome
This study tests a new gene therapy called ION337 designed to treat Dravet syndrome, a severe childhood epilepsy caused by a SCN1A gene mutation. The therapy is given as a spinal fluid injection and aims to reduce seizures in children ages 2–12.
Ann Arbor, MichiganAges 2–12 - NCT07531251RecruitingPhase 4
Barth Syndrome Heart Treatment Study
This trial tests a medicine called elamipretide (4TAZ) in boys with Barth Syndrome, a genetic condition affecting the heart and muscles. The goal is to see if this medicine can help improve heart function and how the body uses energy.
Needham, MassachusettsAges 5–55 - NCT07526051Recruiting
Stretching techniques for lower back pain and muscle tightness
This study compares two stretching methods to help relieve lower back pain caused by muscle imbalances. You'll be tested to confirm the pattern of muscle tightness, then receive one of two types of stretching therapy to see which works better for your pain.
Islamabad, Punjab ProvinceAges 25–50 - NCT07526012Recruiting
Stretching techniques for buttock pain from pinched nerve
This study compares two stretching methods to treat piriformis syndrome, a condition where a muscle in your buttock pinches a nerve. The trial tests whether one stretching approach works better than the other for reducing pain.
Islamabad, Punjab ProvinceAges 20–55 - NCT07527663Recruiting
GyroStim therapy for persistent symptoms after concussion
This study tests whether GyroStim—a specialized rotating chair therapy—can help reduce dizziness, balance problems, and thinking difficulties that last more than 4 weeks after a head injury. GyroStim is designed to retrain how your brain and inner ear work together.
Appleton, WisconsinAges 18 years+ - NCT07528248Recruiting
Posture exercises for upper back and neck pain
This study compares two types of gentle posture-correction exercises for people with upper cross syndrome—a condition where your shoulders round forward and your neck posture shifts. The trial tests which approach works better to reduce pain and improve how you stand and move.
Okāra, Punjab ProvinceAges 20–45 - NCT07530302Recruiting
Better ways to adjust CPAP therapy when it isn't working well
This trial tests whether a wearable device called Sunrise can help doctors adjust your CPAP machine better than standard sleep tests. If your current CPAP isn't stopping all your breathing pauses, this study may help find the right adjustments for you.
GrenobleAges 18–85
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Common questions
- Are there clinical trials for down syndrome?
- Yes. Clin2 currently lists 3,055 recruiting down syndrome studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a down syndrome trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a down syndrome trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.