Clinical trials
Down Syndrome clinical trials
Below are recruiting down syndrome clinical trials, each written for real people, not researchers. We’re tracking 3,057 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07344012Recruiting
Parenting hopes in women with Turner syndrome
This study looks at women with Turner syndrome who wanted to become parents. It aims to understand what support they received and what happened with their parenting plans.
StrasbourgAges 18–40 - NCT06774534Recruiting
SerpinB3 protein in acute respiratory distress
This study looks at a protein called SerpinB3 and its role in severe lung inflammation (ARDS). It may help doctors understand how ARDS develops and find new ways to treat it.
Padova, PDAges 18 years+ - NCT02378805Recruiting
Alport syndrome registry to help delay kidney failure
This is a registry that collects information from people with Alport syndrome to better understand the disease and how to delay kidney failure. It may help researchers learn which factors and treatments are most important over time.
Göttingen, Lower SaxonyAges Any age - NCT07334912RecruitingPhase 2
Study of AEF0217 for people with Down syndrome
This study tests if an investigational drug called AEF0217 can help improve thinking and daily living skills in people with Down syndrome. It's for ages 16-32 who have a caregiver to support them throughout the trial.
BordeauxAges 16–32 - NCT07339930Recruiting
Understanding PCOS types in women
This study looks at the different types of PCOS (polycystic ovary syndrome) in women who are seen at the Strasbourg University Hospital. It aims to better understand the condition and its features.
StrasbourgAges 18–49 - NCT07339904Recruiting
Bowel Function After Rectal Cancer Surgery
This study follows people with rectal cancer who have surgery to remove part of the rectum. It looks at how bowel function changes over time, and whether different treatments before surgery affect recovery.
Edegem, AntwerpAges 18 years+ - NCT07342205RecruitingPhase 2/Phase 3
Fecal transplant for sepsis-related lung injury
This study tests if transferring healthy gut bacteria (fecal microbiota transplant) can help people with acute lung injury caused by sepsis. It aims to reduce inflammation and improve breathing.
Shanghai, PutuoAges 18 years+ - NCT03689842Recruiting
Testing living-donor uterine transplant for MRKH
This study tests whether transplanting a uterus from a living related donor can be done safely and can help patients with MRKH type I achieve pregnancy. It also checks risks and safety issues for both the donor and recipient.
SuresnesAges 18–65 - NCT07329699Recruiting
AI-Guided Heart Artery Pressure Test vs Standard Test
This study compares a new artificial intelligence (AI) method to measure blood flow in your heart arteries (called Medipixel FFR) with the standard invasive method. If you are scheduled for a heart angiogram or stenting and have a moderate blockage (40-90% narrowing) that doctors are unsure about, this AI tool may help decide the best treatment for you.
Seoul, Select StateAges 19 years+ - NCT07328048Enrolling by invitation
Senobi and aerobic exercise for PCOS
This trial compares two types of exercise—Senobi (a gentle hand-and-breath routine) and aerobic exercise—to see which better helps women with PCOS. It may improve menstrual regularity and help with weight management.
Lahore, Punjab ProvinceAges 18–35 - NCT07327606Recruiting
Heart, kidney, and metabolism health study
This study follows people with different stages of heart-kidney-metabolic syndrome to understand what factors affect their health over time. It aims to find better ways to predict and manage the condition.
Beijing, Beijing MunicipalityAges 18–85 - NCT07330297Recruiting
Breath test for metabolic syndrome and obesity health
This study uses a breath test to see if it can tell the difference between people with metabolic syndrome, those with obesity but otherwise healthy, and healthy controls. It aims to find a simple way to check metabolic health without blood draws.
MoscowAges 18 years+ - NCT03675087Recruiting
Testing how exercise affects symptoms in ME/CFS
This trial studies how people with ME/CFS respond to an exercise test. It may help researchers understand what kind of exercise response is typical and how it relates to symptoms.
MadridAges 18–65 - NCT06867159Recruiting
Muscle relaxation techniques for IT band syndrome
This study compares two gentle muscle-relaxing techniques to treat iliotibial (IT) band syndrome, a common cause of outer knee pain. It may help if you have had outer knee pain for more than 3 months and are between 19 and 45 years old.
Rawalpindi, Punjab ProvinceAges 19–45 - NCT05803993Recruiting
Fecal transplant to ease constipation in irritable bowel syndrome
This trial tests whether transferring stool bacteria to the gut (fecal microbiota transplantation) can reduce symptoms of irritable bowel syndrome with constipation. It may help by changing the gut microbiome, but you must meet safety and health requirements.
RomaAges 18 years+ - NCT05803980Recruiting
Fecal transplant to ease IBS diarrhea symptoms
This study tests whether fecal microbiota transplantation (a stool-based treatment to change gut bacteria) can reduce symptoms of irritable bowel syndrome (IBS) that comes with diarrhea. You may be eligible if you’re an adult with diarrhea-predominant IBS and recent colonoscopy results that rule out other intestinal diseases.
RomaAges 18 years+ - NCT06765265RecruitingPhase 4
Comparing two statins' effect on vitamin D after heart attack
This study compares two common statins (atorvastatin and rosuvastatin) to see how they affect vitamin D levels in people who have recently had a heart attack or unstable angina. It may help doctors choose the best statin for your heart and vitamin D health.
Lahore, Punjab ProvinceAges 18–65 - NCT07319845RecruitingPhase 2
Study of a new drug for anemia in lower-risk myelodysplastic syndromes
This trial tests an investigational drug, TAK-226, for people with lower-risk myelodysplastic syndromes (MDS) who have anemia. The study aims to see if the drug can help improve blood counts and reduce the need for red blood cell transfusions.
Tokyo, Bunkyo-kuAges 18 years+ - NCT07319832Recruiting
Teduglutide study for children with short bowel syndrome
This trial tests the medicine teduglutide in children (ages 1–17) with Short Bowel Syndrome who need IV nutrition. The goal is to see if teduglutide can help them reduce or stop IV nutrition.
Guangzhou, GuangdongAges 1–17 - NCT07324005Recruiting
Ultrasound-guided carpal tunnel release and injection for carpal tunnel syndrome
This trial tests a new treatment for carpal tunnel syndrome that uses ultrasound to guide a needle to release a tight ligament in the wrist and inject a sugar-water solution around the nerve. This may help relieve pain and numbness without surgery.
TaipeiAges 20–80 - NCT07322185Enrolling by invitation
Comparing two bodywork methods for piriformis syndrome
This study compares two hands-on treatments, Stecco-fascial manipulation and Rolfing, for people with piriformis syndrome—a condition that causes buttock pain. The goal is to see which approach works better for reducing pain and improving movement.
Sambrial, Punjab ProvinceAges 25–45 - NCT07324343Recruiting
Education for shoulder pain: which patients benefit most?
This study tests whether patients with different types of shoulder pain respond better to learning about their condition through education alone. You will receive information and advice to help you manage your pain without injections or surgery.
IstanbulAges 18–65 - NCT07324733Recruiting
PSMA PET scan for Sjögren's syndrome
This study uses a special PET scan called PSMA to look at inflammation in Sjögren's syndrome, comparing the results with another type of PET scan (FAPI). It may help doctors better understand the disease and find new ways to track it.
BeijingAges 18–80 - NCT07318987Recruiting
Nerve release surgery for knee pain relief
This study tests if surgically releasing a nerve in the knee (the saphenous nerve) can reduce pain in people with patellofemoral pain syndrome (pain around the kneecap). If you've had anterior knee pain for at least six weeks and the nerve test is positive, this trial may offer relief.
CairoAges 18–35
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Common questions
- Are there clinical trials for down syndrome?
- Yes. Clin2 currently lists 3,057 recruiting down syndrome studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a down syndrome trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a down syndrome trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.