Clinical trials
Down Syndrome clinical trials
Below are recruiting down syndrome clinical trials, each written for real people, not researchers. We’re tracking 3,057 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06088030RecruitingPhase 2
Arsenic trioxide plus chemo for p53-mutated childhood cancer
This trial tests if adding arsenic trioxide to standard chemotherapy can help children with cancers that have a certain p53 gene change. The goal is to see if the drug can reactivate the broken p53 protein to fight the tumor.
Guangzhou, GuangdongAges Up to 18 years - NCT06209346Recruiting
Remote physical therapy for chronic pelvic pain from endometriosis
This trial tests if a physical therapy program done at home through video calls can help reduce chronic pelvic pain in people with endometriosis. If you have ongoing pelvic pain and have already had medical or surgical treatment, this study may offer a new way to manage your pain.
Alcalà de Henares, MadridAges 18–55 - NCT05898269Recruiting
Predicting fluid needs while lying face down in ARDS
This study tests a way to predict whether you will benefit from a fluid bolus (a small amount of IV fluid) while you are lying face down for ARDS. It uses continuous heart monitoring to guide or evaluate fluid decisions and may help clinicians avoid too much or too little fluid.
Clermont-FerrandAges 18 years+ - NCT06215222Recruiting
Studying gut bacteria in IBS and digestive issues
This study uses a tiny capsule to collect samples from your small intestine to learn about gut bacteria in people with IBS or other functional gut disorders. It could help researchers understand what causes digestive symptoms.
Redwood City, CaliforniaAges 18–70 - NCT07860840Recruiting
Visual training before robot-assisted walking for stroke survivors
This study tests whether a special visual training program before using a walking robot can improve walking recovery in people who have had a stroke or similar brain injury within the last 6 months and have trouble sensing their affected side. If you join, you might get this extra visual practice to help your brain relearn movement.
Negrar, ItalyAges 18–80 - NCT05384691RecruitingPhase 2
Luspatercept for anemia in lower-risk MDS not needing transfusions
This Phase 2 trial studies whether luspatercept can improve anemia in people with lower-risk myelodysplastic syndrome (MDS) who do not currently need red-blood-cell transfusions. It’s also looking to see if the benefit is similar whether or not you have ring sideroblasts.
BerlinAges 18 years+ - NCT06248957Recruiting
Immune system study for people with hard-to-treat immune diseases
This study aims to understand the immune system in people who have immune problems or whose immune-related diseases are not helped by standard treatments. It may lead to better ways to diagnose and treat these conditions.
StockholmAges Any age - NCT05531240Recruiting
Comparing two procedures for an enlarged prostate
This study compares two common procedures for treating an enlarged prostate, a condition where the prostate grows and blocks urine flow. One procedure removes part of the prostate through the urethra, while the other blocks the blood supply to shrink it.
Helsingborg, Region SkånesAges 45 years+ - NCT06250699Recruiting
Rapid recovery after urologic surgery
This trial tests a program to help patients recover faster after urologic surgery. It focuses on making sure you heal well and get back to your normal life quickly.
Wuhan, HubeiAges 18–70 - NCT03252795Recruiting
Uterus transplant for women with uterine absence
This trial tests whether receiving a uterus transplant can allow someone with uterine absence to carry a pregnancy. It also looks at whether the procedure is safe for the patient and supports a future baby using frozen embryos.
GhentAges 18–38 - NCT06265038Recruiting
Study of a new implant for lower back fusion surgery
This study tests a new implant called ReSpace TiCell Cage for TLIF surgery, which is a procedure to stabilize the lower back by fusing two vertebrae. It may be a good option if you have a degenerative spine condition causing pain or instability and are a candidate for this type of surgery.
Budapest, Pest CountyAges 18–80 - NCT05248165Recruiting
Heart artery disease patients having stent placement
This study enrolls adults with blocked heart arteries who need a procedure called PCI (stent placement). It collects real-world information to help understand and improve care for people like you.
NaplesAges 18 years+ - NCT03742011Recruiting
Study of babies born to mothers with PCOS in Guangzhou
This study looks at children born to mothers who have polycystic ovary syndrome (PCOS). It aims to learn about their health by following families in Guangzhou over time.
Guangzhou, GuangdongAges Up to 18 years - NCT07871149Recruiting
Perimenopausal symptom study for women with sleep apnea
This study tests whether treating sleep apnea can help women with menopause-related symptoms. It uses a home sleep test to check for sleep apnea and may offer treatment options to improve sleep and quality of life.
Chicago, IllinoisAges 18–40 - NCT07859020Recruiting
AI-assisted diagnosis of fast heart rhythms from ECG
This study uses artificial intelligence to analyze ECG recordings and help identify the exact type and location of fast heart rhythms (tachycardia). It may improve the accuracy and speed of diagnosis for conditions like supraventricular tachycardia, Wolff-Parkinson-White syndrome, premature ventricular contractions, and ventricular tachycardia.
Incheon, IncheonAges 19 years+ - NCT06283095Recruiting
Expanding the palate to help sleep apnea
This surgery expands the palate to treat obstructive sleep apnea caused by a narrow upper airway. It may help people with mild to moderate sleep apnea who have a specific type of airway collapse seen on a sleep-endoscopy test.
AsyutAges 18–70 - NCT06046313RecruitingPhase 2
Low-dose decitabine plus venetoclax for older AML/MDS
This trial tests a combination of two drugs (decitabine and venetoclax) at a very low, extended dose for people aged 60 or older who have been newly diagnosed with acute myeloid leukemia or high-risk myelodysplastic syndrome. The goal is to see if this gentler approach is effective and well-tolerated.
Hangzhou, ZhejiangAges 60 years+ - NCT06288633Recruiting
Heart nerve ablation for slow heart rhythm
This test uses a procedure to ablate (destroy) specific nerves in the heart that may be causing your heart to beat too slowly. The goal is to help your heart speed up naturally when needed, so you may avoid needing a permanent pacemaker.
Saint PetersburgAges 18–65 - NCT06226194Recruiting
Genes and weight loss after bariatric surgery
This study looks at how your genes might affect how much weight you lose after gastric sleeve or gastric bypass surgery. You may be able to help doctors better predict weight loss results for future patients.
Lleida, LeidaAges 18–65 - NCT06083363Recruiting
Recovery after severe lung infection
This study follows patients who had severe pneumonia or acute respiratory distress syndrome (ARDS) in the intensive care unit (ICU) to understand how they recover over time. It aims to identify factors that affect recovery trajectories.
Tortosa, TarragonaAges 18 years+ - NCT06294951Recruiting
Brain Scans for Bladder Pain Syndrome
This study uses brain scans (fMRI) to learn how bladder pain syndrome affects the brain. It compares women with bladder pain to those without, to better understand symptoms and improve future treatments.
Shanghai, Shanghai MunicipalityAges 18 years+ - NCT06295484Recruiting
Comparing two breathing support methods for very small babies
This study compares two types of breathing support (nasal CPAP and NIPPV) for very low birth weight preterm infants to see which one works better. The goal is to find the best way to help these babies breathe more easily.
Toronto, OntarioAges 1 day–8 months - NCT06305195Recruiting
Heart rate and risk in metabolic syndrome
This trial looks at how heart rate variability relates to heart disease risk in people with and without diabetes or pre-diabetes. It may help understand which patients need closer monitoring.
AlexandriaAges 18–70 - NCT06037330RecruitingPhase 4
Study of nalbuphine for ARDS after surgery
This trial tests if the drug nalbuphine can help patients with acute respiratory distress syndrome (ARDS) after surgery. It aims to see if it improves breathing and pain while staying in the ICU.
Jinan, ShandongAges 18 years+
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Common questions
- Are there clinical trials for down syndrome?
- Yes. Clin2 currently lists 3,057 recruiting down syndrome studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a down syndrome trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a down syndrome trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.