Clinical trials
Down Syndrome clinical trials
Below are recruiting down syndrome clinical trials, each written for real people, not researchers. We’re tracking 3,057 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT03735563RecruitingPhase 4
Less invasive surfactant timing with different pre-medications
This study tests whether giving a pre-medication before a less invasive lung treatment (surfactant) improves breathing in premature babies. It may help some babies avoid more invasive ventilation while still getting the lung medication they need.
OuluAges Any age - NCT05767619Recruiting
Digital tool to guide care for chest pain calls
This trial tests a digital decision-support tool that helps emergency teams manage people who call for help because of chest pain. It may improve how safely and consistently chest pain is assessed and treated in the ambulance setting.
Kungsbacka, Region HallandAges 18 years+ - NCT05431530Recruiting
Quality of life after rectal surgery for advanced ovarian cancer
This trial studies how patients’ day-to-day quality of life changes after a specific type of rectal/low anterior resection during treatment for advanced ovarian cancer. It may help the medical team understand what symptoms and recovery needs to expect after surgery.
SeoulAges 18 years+ - NCT05924347Recruiting
Imaging study to spot early spine changes in at-risk children
This study uses MRI and physical measurements to look for early signs of scoliosis (a side-bending of the spine) in children who are at higher risk. It may help doctors understand when scoliosis starts and improve early monitoring.
UtrechtAges 8–11 - NCT05937828Recruiting
Caring for children with autoimmune blood disorders in France
This study follows children and teens who have certain autoimmune blood conditions to better understand their illness. It may help doctors learn how these conditions behave over time and improve care.
AmiensAges Up to 17 years - NCT05154370Recruiting
Registry for neuroinflammation diseases and diagnosis categories
This study is a registry that collects information from people diagnosed with certain neuroinflammation conditions. It may help doctors learn how these diseases behave over time and support future research.
Beijing, Beijing MunicipalityAges Any age - NCT06005246Recruiting
Munich ME/CFS Study for Young People
This study is tracking children, teens, and young adults (up to age 25) who developed ME/CFS after an infection. It aims to better understand the condition in younger people.
Munich, BavariaAges Up to 25 years - NCT05936086Recruiting
Testing high-dose cyclophosphamide to treat adult HLH
This trial studies whether giving high-dose cyclophosphamide as an initial treatment works better for adults with HLH. HLH is a serious, overactive immune condition, and the study aims to improve control of the illness and safety.
ChongqingAges 18–65 - NCT05674630RecruitingPhase 4
Drug-coated balloon for coronary artery blockages
This trial studies whether a drug-coated balloon can treat certain coronary artery narrowings in adults with chronic (long-term) coronary disease. It may help prevent re-narrowing after the procedure for people whose tests show the blockage is significant and needs treatment.
LuganoAges 18 years+ - NCT04954690Recruiting
Exercise program after kidney transplant for older adults
This trial tests a structured, coached exercise program for people who recently received a living-donor kidney and are coming from dialysis. It may help improve strength and daily function after transplant, especially if starting fitness is difficult.
San Francisco, CaliforniaAges 50 years+ - NCT06077942Recruiting
FX shoulder replacement study
This study looks at how well FX shoulder replacement devices work for people who received them between 2018 and 2023. It helps doctors learn more about the outcomes of these implants.
Gilbert, ArizonaAges Any age - NCT05918367Recruiting
Registry for surgery to fix pelvic organ prolapse
This is a patient registry study for people having a laparoscopic or robotic operation called ventral mesh rectopexy to treat posterior pelvic organ prolapse. It mainly collects information through questionnaires to better understand outcomes and care, rather than testing a new drug.
BrusselsAges 18 years+ - NCT06026436Recruiting
Predicting clot and bleeding risk in kidney disease patients after a heart attack
This trial tests whether a blood test looking at platelets and tiny cell particles can help predict future blood clots or bleeding in people who have both chronic kidney disease and a recent heart attack. The goal is to improve treatment safety.
MarseilleAges 18–90 - NCT05582512Recruiting
Study of long-term effects in children after COVID-19
This study looks at what long-term health effects children may have after getting COVID-19, and how those effects change over time. You may be asked to share health information and possibly complete a scan that can’t be done if certain metal is present.
Taipei, Chung Cheng DistrictAges Up to 18 years - NCT06128317Recruiting
Heart attack and chest pain registry study
This study is a registry that collects information from people who come to the hospital with heart-related symptoms like chest pain or high troponin levels. It helps doctors better understand different heart conditions and improve care.
Heidelberg, Baden-WurttembergAges 18 years+ - NCT05719935Recruiting
KinematX wrist replacement registry for people with wrist arthritis
This trial is a registry that follows people who get (or already had) a KinematX total wrist replacement. It collects health and recovery information to better understand outcomes for different wrist problems, like arthritis or certain bone alignment issues.
Loma Linda, CaliforniaAges 18–85 - NCT05908214Recruiting
Electrical stimulation for leg stiffness and overactive nerves
This study tests a treatment using high-frequency electrical stimulation to reduce overactive nerve signals that can cause stiff legs, poor ankle control, cramps, or restless legs. It may help improve movement and comfort during walking or at night, depending on the condition.
LausanneAges 18 years+ - NCT05788679RecruitingPhase 2
Use a patient’s genetic test to guide treatment after transplant
This study looks at a personalized lab test to detect small amounts of disease after a stem cell transplant and then decide what treatment comes next. It may help some people with certain bone-marrow diseases stay in remission while avoiding unnecessary treatment.
StockholmAges 18 years+ - NCT06163768Recruiting
Insulin's role in non-diabetic heart attack patients
This study looks at how insulin resistance affects recovery after a heart attack or unstable angina in people without diabetes. It may help understand why some patients have worse outcomes.
Ho Chi Minh City, FiveAges 18–60 - NCT04436978RecruitingPhase 4
Best blood thinner plan for atrial fibrillation after stent
This study compares different blood-thinner (“antithrombotic”) strategies in people with atrial fibrillation or flutter who recently had a stent placed (PCI). It aims to find a plan that lowers clot risk while keeping bleeding risk as low as possible.
AalstAges 18 years+ - NCT04084938Recruiting
Clot-blocking treatment versus surgery for enlarged prostate
This trial compares artery embolization (blocking blood flow to the prostate) with standard surgery for urinary symptoms caused by an enlarged prostate. It may help patients who have moderate-to-severe bladder outlet symptoms and are looking for a treatment option when medicine didn’t work (or they don’t want medicine).
OsloAges Any age - NCT03246334Recruiting
Tracking long-term effects of ICU care in patients
This study follows people who have stayed in an intensive care unit (ICU) to understand long-term effects of ICU treatment. It may help improve future care plans by identifying problems that last after leaving the ICU.
NijmegenAges 16 years+ - NCT07867808Enrolling by invitation
Magnetic therapy versus water therapy for chronic pelvic pain
This study compares two non-drug treatments—pulsed electromagnetic therapy and hydrotherapy (warm water therapy)—to see which one better relieves long-term pelvic pain in men. If you have chronic pelvic pain from non-bacterial prostatitis, this trial could help you find a new way to manage your symptoms.
AmmanAges 42–52 - NCT06187090Recruiting
Supplement therapy for adults with autism
This trial tests whether a specific supplement can help adults with Level 1 autism. It is open only to Italian-speaking participants aged 18–35 who do not have other major mental health or brain conditions.
Udine, UDAges 18–35
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Common questions
- Are there clinical trials for down syndrome?
- Yes. Clin2 currently lists 3,057 recruiting down syndrome studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a down syndrome trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a down syndrome trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.