Clinical trials
Down Syndrome clinical trials
Below are recruiting down syndrome clinical trials, each written for real people, not researchers. We’re tracking 3,055 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07220382RecruitingPhase 4
Botox injections before large hernia surgery
This trial tests if getting Botox shots in the belly muscles before hernia surgery makes the repair easier and more successful. It is for adults who need a planned, open surgery for a large ventral hernia.
Cleveland, OhioAges 18 years+ - NCT07219537Recruiting
Imaging the lower gut with a new capsule
This trial tests a new type of camera capsule that takes pictures of the lower part of your digestive tract. It may be an option for people who are healthy or have Lynch Syndrome and have had a recent normal colonoscopy.
Boston, MassachusettsAges 18–75 - NCT07214415RecruitingPhase 2
Hyperbaric oxygen therapy for veterans with brain injury or mental health issues
This trial tests whether hyperbaric oxygen therapy (breathing pure oxygen in a pressurized chamber) can improve thinking, mood, and quality of life in veterans with mild traumatic brain injury, PTSD, anxiety, or depression. You must have already tried at least one evidence-based therapy like CBT or EMDR.
Boise, IdahoAges 18–75 - NCT07216326Recruiting
Depression help for Black and Latinx youth
This trial tests a program to help Black and Latinx teens and young adults with depression. It involves in-person sessions to learn coping skills and support.
Chicago, IllinoisAges 15–20 - NCT03642002Recruiting
Music therapy for adults on breathing machines in the ICU
This trial tests whether music therapy can improve comfort and recovery for adults who need a breathing machine (mechanical ventilation) in the ICU for at least 48 hours. It may help with stress, mood, and other ICU-related symptoms while you are in critical care.
New York, New YorkAges 18 years+ - NCT06851156Recruiting
Brain stimulation for disorders of consciousness after severe injury
This trial tests a new type of brain stimulation called transcranial temporal interference stimulation to see if it can help people with severe brain injury who are in a vegetative or minimally conscious state. It uses gentle electrical currents to try to improve awareness and recovery.
Xi'an, ShaanxiAges 18–65 - NCT05698446Recruiting
Compare ankle surgery options for lateral ankle instability
This study compares different surgical techniques to treat ongoing (chronic) pain and instability on the outside of the ankle. If you qualify, your care team will determine which surgery approach best fits your situation and then track your outcomes.
BeijingAges 18–60 - NCT06161805RecruitingPhase 3
Esketamine for chronic pain from endometriosis
This trial tests if esketamine, a nasal spray, can reduce chronic pelvic pain in women with endometriosis that hasn't improved with standard painkillers. You may qualify if you have severe pain and are scheduled for endometriosis surgery.
DelftAges 18–50 - NCT07205614Recruiting
Good Pain Consultation for Endometriosis
This trial tests a new way to manage pain from endometriosis. It's a 'good pain consultation' designed to help women who have endometriosis and speak Norwegian.
Kristiansand, AgderAges 16–50 - NCT07203469Recruiting
Nature and activity groups for neurodivergent children
This trial explores whether group activities in nature can help neurodivergent children and youth feel better. It is part of a PhD project, with different phases for different groups.
Kristiansand, AgderAges 5–18 - NCT07208058RecruitingPhase 3
Testing plonmarlimab for blood cell overactivation in people with rheumatic disease
This trial tests a new drug called plonmarlimab for people with a rheumatic (joint or immune) disease who also have a dangerous overreaction of their immune system called HLH (or MAS). The goal is to see if the drug can help when high-dose steroids have not worked or are not an option.
Beijing, Beijing MunicipalityAges 16–80 - NCT07209527Enrolling by invitationEarly Phase 1
Truway diagnostic tools in primary care
This trial tests new diagnostic tools that doctors can use in primary care. Researchers want to see if these tools help find the right diagnosis faster and more accurately.
New York, New YorkAges Any age - NCT06462365RecruitingPhase 1
Preventing GvHD after stem cell transplant for blood cancers
This trial tests a new way to prevent graft-versus-host disease (GvHD), a common complication after a stem cell transplant. It is for people with certain blood cancers who are getting a stem cell transplant from a half-matched family member or unrelated donor.
Duarte, CaliforniaAges 18 years+ - NCT07206537Recruiting
Vitamin K2 to prevent steroid bone loss in children
This study tests whether vitamin K2 can help prevent bone loss caused by steroid treatment in children with nephrotic syndrome. If your child meets the requirements, taking vitamin K2 may protect their bones while they receive steroids.
CairoAges 1–16 - NCT07206394Recruiting
Scar massage for pain after breast cancer surgery
This trial tests if a gentle scar massage technique called ScarWork can help reduce pain that continues after breast cancer surgery and radiation. If you are at least 6 months past radiation and still have pain, this study may be a good fit for you.
LondonAges 18 years+ - NCT07211529Recruiting
Nerve block during chest surgery to reduce complications
This trial tests whether a numbing injection near the spine (paravertebral block) given during keyhole chest surgery can lower the risk of problems after surgery. It might help patients recover more comfortably.
Wuhan, HubeiAges 18–80 - NCT07205523Recruiting
High-altitude blood study for stem cell transplant patients
This study observes how blood and stem cell transplants work for patients with blood diseases at high altitude. It aims to learn more to help future patients.
Xining, QinghaiAges Any age - NCT06355583RecruitingPhase 2
Gut bacteria transplant before stem cell transplant
This trial tests whether giving a transplant of healthy gut bacteria (fecal microbiota transplant) before a stem cell transplant can improve outcomes for people with certain blood cancers or bone marrow disorders.
Birmingham, EnglandAges 18 years+ - NCT06590324RecruitingPhase 2/Phase 3
Study of Apabetalone for long COVID
This trial tests an experimental drug called Apabetalone for people with long COVID. You may be eligible if you have type 2 diabetes, take or are willing to take dapagliflozin, and have had long COVID symptoms for at least 2 months after your COVID infection.
AmmanAges 18 years+ - NCT06932328RecruitingPhase 2
Granules for acute sore throat with wind-heat pattern
This trial tests whether Qinqiao Yan Shu Granules can help adults with acute pharyngitis (sore throat) that started within 48 hours. You must have a specific pattern called wind-heat invading the exterior, and at least moderate throat pain.
Harbin, HeilongjiangAges 18–65 - NCT07197944RecruitingPhase 3
Glepaglutide for short bowel syndrome
This trial tests a new medication called glepaglutide to see if it can help people with short bowel syndrome (SBS) who need IV nutrition or fluids at least 3 days a week. The goal is to reduce or even stop the need for these IV treatments.
Chicago, IllinoisAges 18–90 - NCT07197255Recruiting
Gene study of cumulus cells in CAPA-IVM for PCOS patients
This study looks at gene activity in cumulus cells (cells that surround the egg) during a special type of in vitro maturation (CAPA-IVM) for women with polycystic ovary syndrome (PCOS). It may help doctors better understand how to improve this treatment for women with PCOS.
Ho Chi Minh CityAges 18–38 - NCT07199998Recruiting
How tampons and cups affect your vaginal health
This study looks at how tampons and menstrual cups affect your body's natural defenses and the healthy bacteria in your vagina. You might join if you are a healthy woman between 18 and 49 who has regular periods and uses or is willing to use these products.
Paris, Île-de-France RegionAges 18–49 - NCT07197138Recruiting
TMS for depression with long COVID
This trial tests whether accelerated TMS (a brain stimulation treatment) can help people with depression who also have long COVID. It may be an option if your depression hasn't improved enough with medication alone.
Munich, BavariaAges 18–65
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Common questions
- Are there clinical trials for down syndrome?
- Yes. Clin2 currently lists 3,055 recruiting down syndrome studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a down syndrome trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a down syndrome trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.