Clinical trials
Substance Abuse clinical trials
Below are recruiting substance abuse clinical trials, each written for real people, not researchers. We’re tracking 41 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06004726Recruiting
School substance abuse prevention for teens
This trial tests a school-based program to prevent substance abuse in adolescents aged 13-15. It aims to help teens in public schools in Pokhara, Nepal, avoid risky behaviors.
Pokhara, GandakiAges 13–15 - NCT07340554Recruiting
Brain imaging study for teens who use cannabis
This study looks at the brains of teenagers who use cannabis using an MRI scanner. It aims to understand how cannabis affects the developing brain, which might help improve treatment options.
Indianapolis, IndianaAges 14–17 - NCT05606562Recruiting
Free dental care during hospital treatment for drug abuse
This study offers free dental treatment to people who are staying in a hospital for drug abuse treatment. It aims to see how adding dental care can help while you’re getting help for substance use.
Narvik, NordlandAges 18 years+ - NCT06899308Recruiting
Health check for university students
This study checks the health of students at two universities in Germany. It uses online surveys and interviews to monitor well-being over time.
BremenAges 18 years+ - NCT06880705Recruiting
Trans-Led Care Study for alcohol and drug support
This study is testing a program designed by and for transgender adults to help with alcohol or drug use problems. It looks at whether a supportive, community-based approach can improve health and well-being.
Chicago, IllinoisAges 18 years+ - NCT06262958Recruiting
Early help for teen alcohol and substance issues
This study looks at early help for alcohol and substance use in teenagers. The goal is to see if early support can improve outcomes for young people who have been treated at a psychiatric clinic.
KuopioAges 14–19 - NCT03913819Recruiting
Standard treatment for bladder problems caused by substance abuse
This trial tests how well a set “standard” treatment plan works for people with bladder emptying problems caused by substance abuse. You might consider it if you have this specific type of bladder issue and can follow the treatment plan.
ShatinAges Any age - NCT00439049Recruiting
Screening for substance-abuse treatment readiness
This study helps check whether people who want help for substance use (like cocaine, opiates, or alcohol) are ready to start a treatment program. It may improve how treatment is matched and started, though you must be able to commit for several months.
Houston, TexasAges 18–60 - NCT05897164Recruiting
Mobile app to help teens cut back on substance use
This study tests a mobile app designed to help teens who use alcohol or drugs cut back or stop. You and your teen would use the app together and get support from the study team by text.
Baltimore, MarylandAges 13 years+ - NCT06856148Recruiting
Improving substance misuse prevention research use in state policy
This study aims to better share research on preventing substance misuse with state policymakers. It is for state-level public officials who help make or influence policy.
University Park, PennsylvaniaAges Any age - NCT07281261Recruiting
Nerve stimulation for alcohol use disorder
This study tests whether a mild nerve stimulation device (tAN) can help reduce alcohol cravings and withdrawal. It's for people with moderate to severe alcohol use disorder who are going through withdrawal and do not use tobacco.
Houston, TexasAges 18–64 - NCT06743282Enrolling by invitation
Study on mobile support for substance use in primary care
This trial tests a program called Senyo Health that provides support through text messages and video calls for people with substance use concerns. It aims to help you manage your substance use while working with your primary care doctor.
Scottsdale, ArizonaAges 18 years+ - NCT06961838Recruiting
Breathing muscle training for substance use recovery
This study tests whether a breathing exercise device can help people recovering from substance use disorder. It may improve how well your breathing muscles work and support your overall treatment.
Istanbul, TurkeyAges 18 years+ - NCT06788587RecruitingPhase 2
Long-term stimulant for methamphetamine recovery
This study tests whether a high dose of a stimulant medication (lisdexamfetamine, an ADHD medicine) taken over many weeks can help people who have already completed a methamphetamine treatment program to stay off meth, reduce use, or avoid relapse.
Montreal, QuebecAges 18–55 - NCT06852170Recruiting
Data-driven decisions for substance use services
This trial helps decision-makers use data to improve substance use services and prevent overdoses. It is for professionals who shape policy or run programs in behavioral health, public health, law enforcement, or advocacy.
Eugene, OregonAges 18 years+ - NCT06065553Recruiting
Prevalence of mental health issues in homeless or precarious people in Cayenne
This study looks at how common mental health and substance use problems are among people in difficult living situations in Cayenne. Understanding this can help create better support services.
CayenneAges 18–99 - NCT06413979Recruiting
Family support program for teens with substance use and mood or anxiety issues
This trial offers a family support program for teens with both substance use and internalizing problems like depression or anxiety. The goal is to help you and your caregiver work together to manage symptoms and improve well-being.
Jacksonville, FloridaAges 13–21 - NCT05964010Recruiting
Parent-and-teen program for teen health visits
This trial offers a structured support program for teenagers and their primary caregiver during a primary care visit. It may help by testing an approach that connects youth and families with resources and support starting at the clinic visit.
New York, New YorkAges 12–17 - NCT05776316Recruiting
Harm-reduction support for adults using opioids
This trial offers harm-reduction services for adults who have been misusing opioids (and sometimes other substances) recently. It’s designed to test support approaches that may reduce risks and improve well-being.
New Haven, ConnecticutAges 18 years+ - NCT03906435Recruiting
Cognitive therapy to prevent problems for very premature NICU babies
This study offers a counseling approach to help prevent “Vulnerable Child Syndrome” in babies born very early and cared for in the NICU. It focuses on support during the early months after birth and compares outcomes for families getting the therapy versus usual support.
Dallas, TexasAges Any age - NCT05489042Recruiting
Brain scan and rTMS study for suicidal thoughts in opioid users
This study looks at brain connectivity using an MRI scan and then treats some people with rTMS (a non-surgical brain stimulation). It’s designed for adults who use opioids and currently have active suicidal thoughts, to better understand and help those symptoms.
Houston, TexasAges 18–64 - NCT05743699Recruiting
Bright Horizons program for Native teens with recent binge drinking
This study tests the Bright Horizons program to help Native American youth who recently had a binge alcohol event. It looks at whether support and skills can reduce risky drinking and improve safety and wellbeing.
Whiteriver, ArizonaAges 10–24 - NCT06627764Recruiting
Family program for Latino immigrant families with teens
This study tests a family-based program to help Latino immigrant parents and their teenagers (ages 12-17) build stronger relationships and address challenges together. It is designed for first-generation immigrant families who speak English or Spanish.
Durham, North CarolinaAges 12–100 - NCT06837662Recruiting
Counseling and peer support for opioid use disorder in primary care
This study tests whether adding counseling and peer support helps people with opioid use disorder and other medical problems stay in treatment. It is for patients seen at Central City Concern in Portland who are starting or restarting medication for opioid use disorder, or who are not yet on medication but want help.
Portland, OregonAges 18 years+
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Substance Abuse trials by city
Studies with a site in or near these metro areas.
Substance Abuse trials by state
Studies with a site anywhere in these states.
Common questions
- Are there clinical trials for substance abuse?
- Yes. Clin2 currently lists 41 recruiting substance abuse studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a substance abuse trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a substance abuse trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.