Clinical trials
Drug Abuse clinical trials
Below are recruiting drug abuse clinical trials, each written for real people, not researchers. We’re tracking 37 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT05818384Recruiting
Health program for Choctaw youth to improve daily habits
This is a community health program for Choctaw Nation of Oklahoma youth that tries to improve habits related to food, movement, and screen time. It may help you build healthier routines for everyday life.
Durant, OklahomaAges 12–19 - NCT05865470RecruitingPhase 1
How age affects smoked and oral THC effects
This early-stage study compares how people in different age groups respond to THC taken by smoking versus by mouth. It aims to understand age-related differences in effects and safety, which could help guide safer use in the future.
Los Angeles, CaliforniaAges 18–65 - NCT06552741Recruiting
Screening for substance and alcohol use studies
This study screens people with or without past or current substance or alcohol use problems. It helps the researchers see if you might qualify for other studies at the NIDA research center.
Baltimore, MarylandAges 18–99 - NCT06859710RecruitingPhase 1
THC and CBD as a harm reduction strategy
This study looks at whether different types of cannabis (containing THC and/or CBD) might help people who use cannabis regularly reduce potential harms. You will be asked to take cannabis in a controlled setting and complete tasks and questionnaires.
Los Angeles, CaliforniaAges 21–55 - NCT02604277Recruiting
Study of suicidal behavior in people with bipolar disorder
This study looks at suicidal thoughts or behaviors in people diagnosed with bipolar disorder. It may help researchers understand what leads to suicidal risk and how to better support safety and treatment.
Atlanta, GeorgiaAges 18–64 - NCT05776316Recruiting
Harm-reduction support for adults using opioids
This trial offers harm-reduction services for adults who have been misusing opioids (and sometimes other substances) recently. It’s designed to test support approaches that may reduce risks and improve well-being.
New Haven, ConnecticutAges 18 years+ - NCT06650267RecruitingPhase 2
Substance use and family violence treatment for fathers
This study tests a treatment program for fathers who have both a substance use disorder and a history of family violence within the last 18 months. The goal is to see if the program helps reduce substance misuse and improve family relationships.
New Haven, ConnecticutAges 18 years+ - NCT07559500RecruitingPhase 1
Study of tirzepatide for alcohol use disorder
This trial tests if tirzepatide, a diabetes drug, affects brain chemistry linked to alcohol use. Researchers want to see if it can help people with mild-to-moderate alcohol use disorder who also have tried stimulants.
Bethesda, MarylandAges 21–65 - NCT06880705Recruiting
Trans-Led Care Study for alcohol and drug support
This study is testing a program designed by and for transgender adults to help with alcohol or drug use problems. It looks at whether a supportive, community-based approach can improve health and well-being.
Chicago, IllinoisAges 18 years+ - NCT06651333Recruiting
Brain scans during opioid addiction treatment
This study uses brain scans to understand how methadone or buprenorphine treatment affects the brain, with the goal of helping people stay in treatment and avoid relapse. You would need to be recently started on one of these medications and be able to undergo MRI scans.
Hartford, ConnecticutAges 18–50 - NCT05606562Recruiting
Free dental care during hospital treatment for drug abuse
This study offers free dental treatment to people who are staying in a hospital for drug abuse treatment. It aims to see how adding dental care can help while you’re getting help for substance use.
Narvik, NordlandAges 18 years+ - NCT03407079RecruitingPhase 2
Study of sucralose’s effects on digestion of drugs
This study tests whether the sugar substitute sucralose changes how your body absorbs and breaks down certain medicines. You’d take sucralose or a placebo for 4 weeks, visit the clinic, and complete required samples and medicine doses during visits.
Bethesda, MarylandAges 18–60 - NCT04927143Recruiting
Using phone incentives to support substance abstinence
This study tests a smartphone app that gives changing rewards to help people avoid drug use. It targets adults in substance treatment and tries to see if incentives can improve abstinence during treatment.
Oconomowoc, WisconsinAges 18 years+
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Common questions
- Are there clinical trials for drug abuse?
- Yes. Clin2 currently lists 37 recruiting drug abuse studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a drug abuse trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a drug abuse trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.