Clinical trials
Drug Effect clinical trials
Below are recruiting drug effect clinical trials, each written for real people, not researchers. We’re tracking 150 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06562816RecruitingPhase 4
Comparing two pain relievers after root canal treatment
This study tests two different pain medicines (trypsin-chymotrypsin and naproxen sodium) to see which one works better for pain after a root canal. It may help you if you need a root canal and are generally healthy.
Karachi, SindhAges 18–45 - NCT07545694Recruiting
Bladder Drug Study for Cancer Patients Undergoing Surgery
This study tests how certain drugs affecting the endocannabinoid system (a natural body signaling pathway) affect bladder muscle function in people with bladder cancer who are preparing for or undergoing surgery. Researchers hope this research will help preserve bladder function during cancer treatment.
RomeAges 18 years+ - NCT07191171Recruiting
Gut bacteria drugs and immunotherapy in lung cancer
This study looks at whether certain drugs (like antibiotics or other gut-bacteria-affecting medications) influence how well immunotherapy works for advanced non-small cell lung cancer. It may help find ways to improve treatment outcomes.
StrasbourgAges 18 years+ - NCT07167550RecruitingPhase 3
Testing Dimephosphon for recent ischemic stroke recovery
This study tests an investigational drug called Dimephosphon to see if it helps people recover from a recent ischemic stroke (a stroke caused by a clot). It is for adults ages 35–80 whose symptoms began 24 to 72 hours ago and who have not received clot-busting treatments.
Vsevolozhsk, Leningradskaya Oblast'Ages 35–80 - NCT05968885RecruitingPhase 4
Compare Botox and combination medicines for overactive bladder
This study tests whether Botox injections work better than a combination of medicines (anti-muscarinics plus a beta-3 medicine) for people whose overactive bladder symptoms did not improve with one medicine alone. It may help by improving bladder control and reducing urgent, hard-to-hold urine leaks or frequent urination.
TaipeiAges 20–90 - NCT06197295RecruitingPhase 4
Combination therapy for overactive bladder in women
This study compares the effectiveness of a combination of medications (solifenacin and mirabegron) versus solifenacin alone with a vaginal estrogen cream for treating women with overactive bladder. It may help those who haven't improved with single medication.
TaipeiAges 40–90 - NCT06479720RecruitingPhase 4
Combination medications plus estrogen for overactive bladder
This trial tests whether adding estrogen therapy to a combination of two bladder medications works better than the medications alone for women with overactive bladder that hasn't improved with standard treatment.
TaipeiAges 40–90 - NCT06479655RecruitingPhase 4
Comparing fentanyl and morphine for ICU sedation
This study compares two different pain and sedation medicines (fentanyl and morphine) given continuously through an IV to help patients who are on a breathing machine (ventilator) in the ICU. The goal is to see which medicine works better and is safer for keeping you comfortable and calm.
Kota Bharu, KelantanAges 18 years+ - NCT06462196Recruiting
Study of Depression, Bipolar Disorder & Suicide Risk
This study looks at how depression, bipolar disorder, and suicide risk naturally change over time. It aims to better understand these conditions so doctors can improve treatments.
Bethesda, MarylandAges 18–120 - NCT06100510Enrolling by invitationPhase 4
Platelet function test in healthy adults
This trial is collecting blood from healthy adults to establish a new reference range for a standard platelet function test. You may be eligible if you do not have any bleeding disorders, are not taking blood thinners or anti-inflammatory medications, and meet other lab criteria.
East Syracuse, New YorkAges 18 years+ - NCT04289142RecruitingPhase 4
Testing memory effects of dexmedetomidine during heart surgery
This study looks at how a sleep medicine called dexmedetomidine affects thinking and memory after heart surgery. It compares cognitive outcomes over time to see if this sedation choice changes long-term brain function.
Vancouver, British ColumbiaAges 60 years+ - NCT01402661Enrolling by invitation
Rheumatoid arthritis drug safety and effectiveness registry
This registry collects real-world information about people with rheumatoid arthritis (RA) to help doctors understand how RA medicines work and their safety. You may be able to join if you’re newly diagnosed or starting certain RA treatments and you’re willing to share consent and basic personal details.
Waltham, MassachusettsAges 18 years+ - NCT07319364RecruitingPhase 1
Fecal transplant study for cancer treatment side effects
This trial tests whether fecal transplants (putting healthy donor bacteria into your gut) can help with side effects like diarrhea, constipation, or nausea caused by cancer treatments. It is for people with advanced gastrointestinal cancer who are about to start their fourth round of chemo or targeted therapy.
Zhejiang, HangzhouAges 18 years+ - NCT05652478RecruitingPhase 2
How HIV prevention drugs affect metabolism in healthy people
This study tests how certain HIV prevention drugs affect the body's metabolism (how it uses energy) in healthy people. It aims to understand side effects before these drugs are used more widely, which could help make future treatments safer.
Bethesda, MarylandAges 18–55 - NCT07524829Recruiting
Phone-based nurse support for breast cancer medication side effects
This study tests whether regular phone check-ins with a nurse can help catch and manage side effects from CDK4/6 inhibitor medications (like palbociclib, ribociclib, or abemaciclib) that you're taking for breast cancer. The goal is to help you stay on treatment safely and feel better.
Asti, ASTIAges 18 years+ - NCT04199026Recruiting
Tiny implanted device delivers drugs to sarcoma tumors
This trial tests an implantable device placed during planned surgery to deliver cancer medicines directly to sarcoma tumors and study how they affect the tumors. It may be an option if your sarcoma has come back or spread and surgery is part of standard care.
Houston, TexasAges 10 years+ - NCT07582887Recruiting
Genetic Testing to Predict Side Effects from Breast Cancer Antibody Drugs
This study examines how genetic differences affect how your body handles three newer breast cancer medications (Sacituzumab Govitecan, Trastuzumab Deruxtecan, or Datopotamab Deruxtecan). A blood test will check your UGT1A1 gene to help doctors predict which side effects you might experience and adjust your treatment accordingly.
Granada, GranadaAges 18 years+ - NCT03770923RecruitingPhase 3
Testing medicines for rheumatoid arthritis activity
This trial studies whether certain medicines can improve how active rheumatoid arthritis is. If you have rheumatoid arthritis and do not have significant liver or kidney problems, you may be able to join.
TantaAges 18 years+ - NCT03770936RecruitingPhase 3
Drugs to reduce liver scarring in chronic hepatitis C
This Phase 3 study tests medicines to see whether they can reduce liver scarring (fibrosis) in people with long-term hepatitis C. If you qualify, you may receive the study treatment and be monitored over time to see how your liver is affected.
TantaAges 20 years+ - NCT05438121Recruiting
Tests a drug-coated balloon to stabilize clogged heart arteries
This trial studies whether a drug-coated balloon can better treat new, narrowed spots in multiple coronary arteries and “stabilize” the plaque. It may help improve blood flow after a procedure called balloon angioplasty for selected patients.
Ansan-si, Gyeonggi-doAges 18–85 - NCT07659418Recruiting
Vitiligo medication safety registry for adults and teens
This registry tracks the safety and effectiveness of vitiligo medications over time. It helps doctors learn how well treatments work for adults and teens with nonsegmental vitiligo.
Waltham, MassachusettsAges 12 years+ - NCT07616648Recruiting
How Opioid Pain Drugs Affect Sleep and Mood in Cancer Patients
This study examines how opioid medications (strong pain relievers) impact sleep quality and emotional well-being in cancer patients with moderate to severe pain. Researchers will track your sleep patterns and mood to better understand these side effects.
HangzhouAges 18–75 - NCT07598058Recruiting
Hand Eczema Treatment Safety and Effectiveness Registry
This registry collects information about how well medications work for chronic hand eczema and how safe they are over time. You'll share your health data and treatment experiences through simple online forms to help doctors better understand which treatments work best.
Waltham, MassachusettsAges 18 years+ - NCT05951660Recruiting
Study sexual side effects in schizophrenia with diabetes
This study looks at how sexual functioning is affected in people with schizophrenia, especially in those who also have diabetes or weight-related risk. It also examines how psychiatric medicines and diabetes/weight factors may be connected, which could help improve care for patients.
SlagelseAges 18 years+
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Common questions
- Are there clinical trials for drug effect?
- Yes. Clin2 currently lists 150 recruiting drug effect studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a drug effect trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a drug effect trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.