Clinical trials
Early Lung Cancer clinical trials
Below are recruiting early lung cancer clinical trials, each written for real people, not researchers. We’re tracking 202 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06495125RecruitingPhase 2
Study of three drugs for a type of advanced lung cancer
This trial tests a combination of two targeted drugs (defactinib and avutometinib) plus an immunotherapy (nivolumab) for people with advanced lung adenocarcinoma that has a specific gene mutation (LKB1) and has stopped responding to prior immunotherapy and chemotherapy. The goal is to see if this new combination can shrink tumors or slow cancer growth.
Atlanta, GeorgiaAges 18 years+ - NCT05292521Recruiting
Quality-of-life program to help early lung cancer decisions
This trial tests a quality-of-life support program meant to help people with early-stage lung cancer think through their treatment choices. It may help you feel more informed and more confident about deciding between treatments like surgery and SBRT.
Buffalo, New YorkAges 18 years+ - NCT05558904RecruitingPhase 1/Phase 2
PET/CT scan to help find early lung cancer
This trial tests a special PET/CT scan to spot early lung cancer by finding specific body processes linked to cancer. It compares scan results in people with lung nodules that are either cancer (lung adenocarcinoma) or likely benign.
Los Angeles, CaliforniaAges 18 years+ - NCT06016569Recruiting
Breath test for early lung cancer in high-risk smokers
This study tests a new breath test to find early signs of lung cancer in people at high risk. It looks for cancer biomarkers in the air you breathe out. If you are a heavy smoker between 55 and 74, this trial may help detect lung cancer earlier.
BrnoAges 55–74 - NCT05570825RecruitingPhase 2
Study drug SX-682 with pembrolizumab for advanced lung cancer
This trial tests SX-682 plus pembrolizumab (an immunotherapy) to treat metastatic or recurrent non-small cell lung cancer (NSCLC). It aims to see how well the combination works and whether it can shrink or control the cancer in people whose tumors have enough PD-L1.
Seattle, WashingtonAges 18 years+ - NCT05557474Recruiting
Test of a lung cancer prognosis kit after early tumor removal
This study tests a lab “prognosis kit” to better predict how early-stage lung cancer may progress after the tumor has been fully removed. You may be asked to provide tumor samples and possibly blood/body fluid samples so researchers can validate the kit.
Taichung, TaiwanAges 20 years+ - NCT05502523Recruiting
Blood test DNA levels after lung surgery
This study looks at how different lung surgical techniques affect levels of tumor DNA in the blood before and after surgery for early-stage lung cancer. It may help doctors choose surgical approaches and use a blood test to monitor cancer after surgery.
Abington, PennsylvaniaAges 18 years+ - NCT05366881Recruiting
Blood test study to spot early cancer signal and cancer leftovers
This observational study checks whether a blood test (a “cfDNA” test) can detect early signs of cancer or small amounts of cancer left after treatment. It may help doctors use a simple blood sample to improve cancer detection and follow-up.
Duarte, CaliforniaAges 40 years+ - NCT05334069Recruiting
Blood test study for early cancer detection in patients
This study collects blood from people with cancer and people without cancer (or with possible cancer) to test whether new blood tests can detect cancer earlier. Your blood samples help researchers evaluate how well these tests work.
Anchorage, AlaskaAges 40–75 - NCT05142033Recruiting
Cancer or precancer testing using DNA sequencing results
This trial helps doctors study and analyze cancer- or precancer-related DNA information. If you’re 18 or older and can consent, your results may help researchers understand the biology of your condition and guide future care.
Marshall, MinnesotaAges 18 years+ - NCT03546829RecruitingPhase 1
Testing targeted radiation plus short anti-microbial treatment
This early safety study tests a combination of focused radiation and a targeted anti-microbial (antibiotic/antifungal/antiviral/anti-parasite) plan for certain lung cancer that is starting to progress in a few spots. It aims to see whether this approach is safe and helps control the small areas of progressing cancer after prior treatment.
Philadelphia, PennsylvaniaAges 18 years+ - NCT04354064Recruiting
Blood DNA test to see early treatment response in solid tumors
This study looks at circulating tumor DNA, which is tiny bits of DNA found in blood, to help assess how solid tumors are responding early. It uses blood samples from healthy adults who are willing to donate.
St Louis, MissouriAges 18 years+ - NCT03563976Recruiting
Imaging study for lung cancer outcomes
This study looks at medical images from people with lung cancer to see how image findings relate to outcomes. It may help doctors better understand which imaging features predict results for patients.
Dallas, TexasAges 18–99 - NCT03706027Recruiting
Compare two radiation timing plans for early lung cancer
This trial tests whether two different schedules (timing) of radiation have different side effects in people with early-stage non-small cell lung cancer. It may help reduce or better understand treatment toxicity while still treating the cancer.
Rochester, New YorkAges 18 years+ - NCT02570815RecruitingPhase 1
Fluorescent-guided robotic lung surgery for early lung cancer
This early-stage trial tests a robotic lung surgery that uses a special dye with near-infrared light to help the surgeon remove only the tumor area. If you have a small, early lung cancer, this approach may help improve accuracy while limiting how much lung is removed.
Hamilton, OntarioAges 18 years+ - NCT05732974Recruiting
Using a computer tool to find lung cancer relapse risk
This study uses a machine-learning computer method to identify people with early-stage lung cancer who have a higher risk of the cancer coming back after surgery. If you qualify, your information may help researchers improve how doctors predict relapse and plan follow-up care.
ToulouseAges 18 years+ - NCT07788729Recruiting
Support program for cancer patients and their caregivers
This study tests a program that provides social support and short learning sessions to help cancer patients and their caregivers manage daily life. It aims to improve well-being and care for both patients and their support persons.
Augsburg, BavariaAges 18 years+ - NCT06728865RecruitingPhase 2
Furmonertinib plus Avastin for EGFR+ lung cancer with brain mets
This trial tests a combination of two targeted drugs (Furmonertinib and Avastin) as the very first treatment for people with a specific type of lung cancer (EGFR-mutant non-small cell) that has spread to the brain. The goal is to see how well it works and how safe it is.
Guangzhou, GuangdongAges 15–75 - NCT07034326RecruitingPhase 2/Phase 3
Acupuncture plus immunotherapy after lung cancer surgery
This trial explores whether adding electroacupuncture (a gentle needle treatment with mild electric pulses) to standard immunotherapy after lung cancer surgery can help prevent the cancer from coming back. It is designed for people with early-stage non-small cell lung cancer who have already had chemotherapy.
TianjinAges 18–80 - NCT06907095Recruiting
Early cancer detection study for high-risk individuals
This study tests if a simple blood or fluid test can find cancer early in people with a higher-than-average risk. If you have certain genetic mutations, a strong family history of cancer, or other high-risk conditions, you may be able to join.
VillejuifAges 18 years+ - NCT06816121Recruiting
Blood test for early lung cancer in high-risk smokers
This study is evaluating a blood-based test that might detect lung cancer early, before symptoms appear. Researchers are looking for heavy smokers who have no signs of cancer, as well as those with suspicious lung nodules or confirmed lung cancer, to see if a simple blood draw could help identify cancer sooner.
Oklahoma City, OklahomaAges 30–80 - NCT06743581Recruiting
Cemiplimab and dupilumab before lung cancer surgery
This study tests two drugs, cemiplimab and dupilumab, given before surgery for early-stage non-small cell lung cancer. The goal is to see if these drugs can shrink the tumor and improve outcomes.
Montreal, QuebecAges 18 years+ - NCT06284317RecruitingPhase 3
Durvalumab after chemo and surgery for early lung cancer
This trial tests adding durvalumab (an immunotherapy) after chemotherapy, surgery, and more durvalumab for people with early-stage, operable non-small cell lung cancer. It aims to see if this extra treatment helps prevent the cancer from coming back.
Camperdown, New South WalesAges 18 years+ - NCT06054854Recruiting
Lung Cancer Biomarker Study (BIRD Biobank)
This study collects blood, tissue, and other samples from people with lung nodules, suspected lung cancer, or confirmed lung cancer to find better ways to diagnose and treat the disease. By joining, you help researchers discover new biomarkers that could improve care for future patients.
ToulouseAges 18 years+
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Common questions
- Are there clinical trials for early lung cancer?
- Yes. Clin2 currently lists 202 recruiting early lung cancer studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a early lung cancer trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a early lung cancer trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.