Clinical trials
Effectiveness clinical trials
Below are recruiting effectiveness clinical trials, each written for real people, not researchers. We’re tracking 6,378 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06258863Enrolling by invitation
Comparing incision types in breast reconstruction after mastectomy
This study compares different types of surgical cuts (incisions) used during breast reconstruction after mastectomy. It looks at which incision gives the best cosmetic result and causes the fewest problems. Researchers want to find out which technique is best for you.
Wuhan, Hongshan DistrictAges 18 years+ - NCT06262295Recruiting
Monitoring the safety of AVEIR leadless pacemakers
This study tracks the safety and performance of AVEIR VR LP and AVEIR AR LP leadless pacemakers in people who already have them or will get one. It helps doctors and researchers see how well these small heart devices work over time.
La TroncheAges 18 years+ - NCT06273631Recruiting
Carbohydrate intake patterns for blood sugar control in type 1 diabetes
This study compares different ways of eating carbohydrates to see which pattern helps people with type 1 diabetes manage their blood sugar better. If you have type 1 diabetes and are on insulin, this trial might help you find an eating approach that improves your glucose control.
Nanjing, JiangsuAges 18–70 - NCT06270407RecruitingPhase 4
Tranexamic acid for fewer complications in plastic surgery
This study tests whether applying tranexamic acid directly to the skin during plastic surgery reduces bleeding or other complications compared to a placebo. It may help you heal better after your procedure.
VejleAges 18 years+ - NCT03329313RecruitingPhase 2
Adjusting dialysis salt levels for ICU kidney injury
This study tests whether using a specific salt (sodium) level in the dialysis fluid affects outcomes for adults in the ICU with sudden kidney failure. It may help your care team optimize dialysis settings during acute kidney injury.
Montpellier, MontpellierAges 18–80 - NCT04628663Recruiting
Dexmedetomidine and eye pressure during spine surgeries
This study looks at whether a specific anesthesia-related medicine (dexmedetomidine) affects eye pressure during planned spine operations done with the patient lying face-down under general anesthesia. It may help doctors choose safer anesthesia to reduce risks related to eye pressure changes.
Athens, AtticaAges 18–90 - NCT05840302Recruiting
Pain education program to increase activity in chronic low back pain
This trial studies whether teaching “pain neuroscience” (how pain works in the body and brain) helps people with long-term low back pain move more. It compares an education program as part of a multidisciplinary rehab to usual care during your planned hospital stay.
Lamalou-les-BainsAges 18 years+ - NCT06238765Recruiting
Adolescent Eczema Drug Safety Registry
This registry tracks the safety and effectiveness of medications used for moderate to severe atopic dermatitis (eczema) in adolescents aged 10 to 15. It helps doctors understand how well these treatments work and what side effects might occur over time.
Waltham, MassachusettsAges 10–15 - NCT06246136Recruiting
Laser treatment for glaucoma during cataract surgery
This study tests a new laser treatment (ELIOS) for people with open-angle glaucoma who also need cataract surgery. It aims to see if the laser is safe and effective at lowering eye pressure while removing the cataract.
LeuvenAges 40 years+ - NCT06083090Recruiting
Yoga therapy vs. physiotherapy for axial spondyloarthritis
This study compares yoga therapy to standard physical therapy for people with moderately active axial spondyloarthritis (a type of inflammatory arthritis affecting the spine and joints). The goal is to see if yoga can help improve symptoms and function as well as or better than physiotherapy.
BobignyAges 18 years+ - NCT06237218Recruiting
Occupational therapy to prevent falls in older adults with dementia
This program tests whether a special type of home-based occupational therapy (called COTID) can help older adults with dementia avoid falling again after a fall that sent them to the hospital. It compares this new approach to usual occupational therapy care.
LimogesAges 75 years+ - NCT06236607Recruiting
Artificial pancreas trial for adults with type 1 diabetes
This trial tests a hybrid closed-loop system that automatically adjusts insulin delivery. It may help you manage your blood sugar more easily if you currently give yourself daily insulin shots.
Boston, MassachusettsAges 18–75 - NCT06249984Recruiting
Comparing moist snuff products for adult users in rural areas
This study compares different types of moist snuff to understand how they affect users. It may help find ways to reduce harm for people who use smokeless tobacco.
Columbus, OhioAges 21 years+ - NCT06238960Recruiting
Home-based physical therapy after hip replacement
This trial tests whether doing physical therapy at home using video calls works as well as in-person therapy after a hip replacement. You would continue your rehab with the same team, but from home.
Bologna, ItaliaAges 50–80 - NCT06230861Recruiting
Quercetin supplement for heart and metabolic health
This study tests whether taking a supplement called quercetin (a natural plant compound) improves heart and metabolic health markers in healthy adults. You'd take the supplement for a period of time, and researchers will measure things like blood sugar and cholesterol.
Preston, LancashireAges 18–65 - NCT06247839RecruitingPhase 3
Psilocybin for depression: changing self-focus
This trial tests whether a single dose of psilocybin can help people with treatment-resistant depression by changing how they focus on themselves. It aims to understand how psilocybin affects brain activity and self-related thinking.
Charlestown, MassachusettsAges 18–55 - NCT06246929Recruiting
Healthy aging for Black adults with chronic pain and memory concerns
This study tests a program to help Black adults aged 50+ manage chronic pain and early memory changes. It compares two approaches to see which works better for improving daily life and thinking skills.
Boston, MassachusettsAges 50 years+ - NCT06245681Recruiting
How Hormone Therapy Affects the Heart and Liver
This study looks at how cross-sex hormone treatment affects the heart and fat in the liver. It aims to help understand the safety of hormone therapy in transgender individuals.
Vienna, State of ViennaAges 18–99 - NCT06245343Recruiting
Breathing exercise study for lung cancer survivors
This study tests whether a special breathing exercise (functional inspiratory muscle training) can help people recover better after lung cancer surgery. If you are between 18 and 80, have completed your lung cancer treatment, and are now in remission, this program may improve your breathing and strength.
Ankara, ÇankayaAges 18–80 - NCT06230614Recruiting
Study of diluent volume for inhaled colistin
This trial tests how the amount of liquid mixed with colistin affects treatment when inhaled by patients on ventilators. The goal is to find the best way to give this antibiotic therapy.
New Taipei CityAges 18–100 - NCT06229483RecruitingPhase 3
Does tranexamic acid reduce bleeding during brain tumor surgery?
This study tests whether a medication called tranexamic acid (TXA) given during brain tumor surgery can reduce bleeding. If you are having a standard craniotomy for a tumor and don’t have certain health risks, you may be eligible.
Halifax, Nova ScotiaAges 18–80 - NCT06237101Recruiting
Effect of Remifentanil on Burst Suppression Ratio
This study tests how remifentanil (a pain medicine given during surgery) affects brain activity patterns. It may help doctors better control anesthesia for safer surgeries.
Santiago, RMAges 18–60 - NCT06248073Recruiting
Online program and task training for Parkinson's disease
This study tests an online program and task-based training to help people with mild Parkinson's disease improve their movement and reaching ability. It is designed for people who can still sit and reach for objects without major tremors or other health problems.
Linkou DistrictAges 45–70 - NCT06229990RecruitingPhase 4
Using furosemide stress test to stop kidney replacement therapy
This study tests whether a furosemide (a water pill) stress test can help doctors decide when to safely stop continuous kidney replacement therapy in ICU patients with severe acute kidney injury. It may allow you to come off the machine sooner if your kidneys respond well.
Chiang MaiAges 20 years+
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Common questions
- Are there clinical trials for effectiveness?
- Yes. Clin2 currently lists 6,378 recruiting effectiveness studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a effectiveness trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a effectiveness trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.