Clinical trials
Effectiveness clinical trials
Below are recruiting effectiveness clinical trials, each written for real people, not researchers. We’re tracking 6,378 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06083766Recruiting
Hormone Therapy Effects on Metabolism in Transgender Adults
This study looks at how long-term gender-affirming hormone therapy affects your body's metabolism and energy use. Researchers want to understand these changes better to improve care for transgender and gender-diverse people.
Rochester, MinnesotaAges 18–40 - NCT06082531Recruiting
Platelet-rich plasma injection for knee osteoarthritis
This study tests whether injecting platelet-rich plasma (PRP) from your own blood can help knee pain caused by osteoarthritis or injuries to the cartilage and meniscus. It may be an option if you are between 20 and 60 years old and have not had recent steroid shots or certain health problems.
Xi'an, ShannxiAges 20–60 - NCT06081218Recruiting
Exercise and brain function in cannabis users
This study looks at how a single session of exercise affects brain function and memory in regular cannabis users compared to non-users. You will exercise on a bike or watch a movie, and then do memory tests and a blood draw.
LilleAges 18–35 - NCT06089915Recruiting
Robot-assisted arm exercise for cervical spinal cord injury
This trial tests a robot that helps move your arms if you have a cervical spinal cord injury. It may improve arm strength and function through guided exercise.
LjubljanaAges 18 years+ - NCT06091228Recruiting
Tongue scraping for bad breath with gum disease treatment
This trial checks if adding tongue scraping to regular gum disease treatment can help reduce bad breath more than gum treatment alone.
LeuvenAges 18 years+ - NCT06081426Recruiting
Ketogenic diet for bipolar disorder brain study
This study looks at how a ketogenic diet (very low carb, high fat) might affect brain function in people with bipolar disorder. Participants will follow the diet and have brain scans and blood tests to see how it helps mood and energy levels.
Pittsburgh, PennsylvaniaAges 18–40 - NCT06092281Recruiting
Can questionnaires improve follow-up after ESD?
This trial tests whether sending questionnaires and feedback helps patients keep up with their follow-up appointments after having a precancerous growth removed from the digestive tract (a procedure called ESD). It aims to see if this approach can make a difference in how well patients stick to their recommended check-ups.
Xi'an, ShaanxiAges 18–80 - NCT06099730Recruiting
Pulsed field ablation for atrial fibrillation
This trial tests a new method called pulsed field ablation to treat atrial fibrillation (AF), a type of irregular heartbeat. It aims to safely stop AF episodes by targeting specific areas in the heart, and may help people with paroxysmal (coming and going) or persistent AF who haven't had this procedure before.
Jonesboro, ArkansasAges 18–80 - NCT06090253Recruiting
Sport exercise program for healthy aging over 60
This trial tests a program that uses sports and exercise to help people over 60 stay healthy and active. It looks at both how well the program works and how easy it is to put into practice.
Hong KongAges 60 years+ - NCT06092671Recruiting
Can FPCA prevent confusion in young kids after surgery?
This study tests whether a medicine called FPCA can prevent sudden confusion (delirium) in young children after surgery. If your child is having short surgery with mask anesthesia for the first time, this study may help them have a smoother recovery.
Wenzhou, ZhejiangAges 2–6 - NCT06099561Recruiting
Support for hard-to-treat self-harm
This study explores what kinds of support work best for people who have tried at least two proven treatments for self-harm without enough relief. It aims to find better ways to help those who continue to struggle.
Lund, Skåne CountyAges 18 years+ - NCT06099379RecruitingPhase 1/Phase 2
How CBD changes THC's effects: a dose study
This study tests different ratios of CBD to THC to see how CBD can change the effects of THC. It may help people who use cannabis occasionally understand how CBD can reduce unwanted side effects.
Montreal, QuebecAges 21–49 - NCT06100510Enrolling by invitationPhase 4
Platelet function test in healthy adults
This trial is collecting blood from healthy adults to establish a new reference range for a standard platelet function test. You may be eligible if you do not have any bleeding disorders, are not taking blood thinners or anti-inflammatory medications, and meet other lab criteria.
East Syracuse, New YorkAges 18 years+ - NCT06096740Recruiting
Talking therapy for PTSD and its effects on the brain
This study looks at how a specific type of talk therapy affects the way your brain processes rewards. You'd join a group that either starts therapy right away or waits a bit before starting. Your brain activity will be scanned with an MRI to see changes.
Austin, TexasAges 18–65 - NCT06096233Recruiting
Exercise and appetite study for men
This study looks at how exercise affects appetite before and after meals. It might help understand how physical activity influences eating habits.
GlasgowAges 18–65 - NCT04513028Recruiting
Beta-glucan with immunotherapy for melanoma immune response
This study tests whether taking beta-glucan alongside pembrolizumab changes how your immune system responds in people with stage III–IV melanoma. It may help researchers understand whether beta-glucan improves immunotherapy activity after cancer has been controlled.
Louisville, KentuckyAges 18 years+ - NCT05616819Recruiting
Morning light program to improve mood in some service members
This study tests whether getting morning light exposure can improve mood for service members who currently have mild or more depression symptoms. You’d follow a plan for morning light over about 6 weeks, and the researchers check changes in mood.
Tucson, ArizonaAges 18–60 - NCT05805397Recruiting
Motivation skills training for schizophrenia or schizoaffective disorder
This study tests whether “Motivation Skills Training” can help people with schizophrenia or schizoaffective disorder. It’s for people who are stable on treatment and can participate in English-speaking sessions.
New York, New YorkAges 18–65 - NCT04502225Recruiting
Trial of bed head elevation for high blood pressure
This study checks whether raising the head of the bed lowers blood pressure while you’re lying down in people with autonomic failure. It may help find a simple positioning change to reduce risks from high lying blood pressure.
Nashville, TennesseeAges 18–85 - NCT05245903Recruiting
Test a supplement and track brain changes with wearable sensors
This study tests whether taking nicotinamide riboside (a form of niacin) affects early memory changes in people with mild cognitive impairment (MCI) or mild Alzheimer’s disease (AD). It also uses passive wearable or sensor data (“digital biomarkers”) to measure changes over time.
Belmont, MassachusettsAges 18–89 - NCT06064890RecruitingPhase 1/Phase 2
Gene therapy trial for genetic frontotemporal dementia
This trial tests a new gene therapy called AVB-101 for people with a specific genetic cause of frontotemporal dementia (FTD). The therapy is given as a one-time injection into the brain to potentially slow or stop the disease.
Columbus, OhioAges 30–75 - NCT06061770Recruiting
Comparing two exercise programs for chronic stroke patients
This trial compares a supervised exercise program in a special facility with a self-guided exercise program at home. It aims to see which is more effective for improving walking and daily activity in people who had a stroke more than 6 months ago.
Marseille, Bouches du RhôneAges 18 years+ - NCT06076304RecruitingPhase 4
Comparing treatments for acute sinusitis
This trial tests whether nasal steroids, nasal irrigation, or oral antibiotics work best for acute sinusitis. It may help if you have ongoing sinus symptoms or a 'double-sickening' pattern after a cold.
Los Angeles, CaliforniaAges 18–75 - NCT06070649RecruitingPhase 1
DMT for Alcohol Use Disorder
This trial tests whether a single dose of DMT, a psychedelic, can help people with alcohol use disorder. It's a small early-phase study to see if the treatment is safe and promising.
New Haven, ConnecticutAges 21–65
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Common questions
- Are there clinical trials for effectiveness?
- Yes. Clin2 currently lists 6,378 recruiting effectiveness studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a effectiveness trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a effectiveness trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.