Clinical trials
Effectiveness clinical trials
Below are recruiting effectiveness clinical trials, each written for real people, not researchers. We’re tracking 6,378 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06121843RecruitingPhase 1
Study of CAR-T cell therapy in combinations for multiple myeloma
This trial tests a new CAR-T cell therapy (called arlocabtagene autoleucel) combined with other drugs for multiple myeloma that has returned or stopped responding. It aims to find a safe and effective dose while tracking how well the treatment works.
Birmingham, AlabamaAges 18 years+ - NCT06108076RecruitingEarly Phase 1
Oral ketones for heart failure and diabetes
This study tests whether taking a special oral ketone supplement can help people with both heart failure and diabetes. It looks at both short-term and long-term effects on heart function and blood sugar control.
San Antonio, TexasAges 18–80 - NCT06129110Recruiting
Weight loss and muscle fat study for adults aged 18-70
This study looks at how losing weight affects the fat that sits inside your muscles (called intermuscular fat). It might help people with overweight to better understand how weight loss can improve muscle health.
Aurora, ColoradoAges 18–70 - NCT06118034RecruitingPhase 3
Colchicine for heart surgery recovery
This study tests whether the drug colchicine can reduce inflammation and protect organs during and after planned heart surgery. It may help people recover better.
Nanjing, JiangsuAges 50–80 - NCT06127316Recruiting
Heel lift height and foot pressure with custom braces
This study tests if changing the height of a heel lift in a custom foot brace can improve how weight is distributed on your foot after a serious ankle or hindfoot injury. If you have pain when walking, this could help find better ways to reduce that pain.
Iowa City, IowaAges 18–65 - NCT06108336Recruiting
How the cerebellum affects thinking and sequencing
This study uses MRI and TMS to understand how the cerebellum, a brain region, helps with cognitive sequencing—putting thoughts or actions in order. It may lead to better treatments for cognitive problems.
Baltimore, MarylandAges 18–50 - NCT06124846Recruiting
Cannabis break and brain changes in teens
This study looks at what happens in the brain when teens with cannabis use disorder stop using cannabis for 6 weeks. It uses MRI scans to see changes in areas that control habits and decisions.
Minneapolis, MinnesotaAges 15–18 - NCT06126315RecruitingPhase 2/Phase 3
Testing acetyl-L-carnitine in early ALS
This study tests a supplement called acetyl-L-carnitine (ALCAR) to see if it can slow the progression of ALS. It is for people in the early stages of the disease who are already taking riluzole and have good lung and muscle function.
SydneyAges 18 years+ - NCT06115603RecruitingPhase 2
Testing CBG for ADHD symptoms
This study tests whether a non-psychoactive compound from hemp called CBG (cannabigerol) can help with ADHD symptoms. You will take CBG capsules or a placebo for several weeks to see if it improves focus and reduces hyperactivity.
Fayetteville, ArkansasAges 18–55 - NCT06121219Recruiting
Can visual retraining after stroke improve sight?
This trial tests whether special computer-based visual exercises can help people whose vision was damaged by a stroke. You would do the exercises at home for several months.
Rochester, New YorkAges 21–80 - NCT06127056Recruiting
Brain stimulation for teens who hurt themselves
This trial tests whether a gentle, non-invasive form of brain stimulation called HD-tACS can help teens who hurt themselves without meaning to die. The stimulation uses electrodes on the scalp to aim electrical signals at specific brain areas, and it is given over several sessions to see if it reduces the urge to self-harm.
Hefei, AnhuiAges 12–18 - NCT06117579Recruiting
Breathing Muscle Training for Sleep Apnea
This trial tests whether a simple breathing exercise (training the muscles you use to breathe in) can improve sleep apnea symptoms in people who already use CPAP. The goal is to see if adding this training helps you feel better or need less CPAP pressure.
OrléansAges 18 years+ - NCT06120764Recruiting
Imagery therapy for chemo-related nausea in children
This study tests if guided imagery (a relaxation technique using mental images) can help reduce nausea and vomiting caused by chemotherapy in children ages 7 to 18. It may offer a drug-free way to manage these side effects.
Ankara, AnkaraAges 7–18 - NCT04781972RecruitingPhase 4
Brain scan study of ADHD effects from methylphenidate
This study uses brain imaging (MRI) to see how methylphenidate affects brain activity in people with ADHD. It may help doctors better understand how this medicine works and who benefits most.
Baltimore, MarylandAges 6–40 - NCT05501262Recruiting
Cryoablation vs steroid injection for Morton’s neuroma pain
This trial compares two ways to treat Morton’s neuroma pain: freezing treatment (cryoablation) versus steroid plus lidocaine injections. It may help people who didn’t improve after trying basic shoe inserts or padding, by seeing which approach works better for symptoms.
Portland, OregonAges 18–105 - NCT05854303Recruiting
Stopping opioids’ effects on swallowing in esophagus problems
This study looks at how stopping opioid pain medicines affects esophagus function (the tube that carries food to the stomach), including in people with or without symptoms. It may help researchers understand what changes to expect after opioid cessation in a pain rehabilitation program.
Rochester, MinnesotaAges 18 years+ - NCT04471909Recruiting
Stent graft for aortic arch problems in high-risk patients
This study tests a new stent graft device to treat problems in the aortic arch, such as aneurysms or chronic dissections, without open surgery. It may help people who are not good candidates for traditional open repair.
Birmingham, AlabamaAges 18 years+ - NCT04094090RecruitingPhase 2
Corneal strengthening treatment for thinning eye shape
This Phase 2 study tests how safe and well a corneal cross-linking device (called PXL-Platinum 330) works for people with corneal ectasia (a thinning/steepening of the cornea). If you qualify, the goal is to help stop or slow further worsening of your cornea shape and improve eye stability.
San Francisco, CaliforniaAges 10 years+ - NCT06100991Recruiting
Generalized Pustular Psoriasis Drug Safety Registry
This registry tracks the safety and effectiveness of GPP treatments in real-world settings. It helps doctors and researchers learn how well current and future medicines work for people with generalized pustular psoriasis.
Waltham, MassachusettsAges 18 years+ - NCT06082037RecruitingPhase 3
Testing belumosudil for chronic lung allograft dysfunction after transplant
This trial tests an oral medication called belumosudil for people with chronic lung allograft dysfunction (CLAD) after a double lung transplant. It may help slow the decline in lung function.
Birmingham, AlabamaAges 18 years+ - NCT06086496Enrolling by invitation
Study of a new drug-releasing stent for heart arteries
This trial tests a new type of stent (a small mesh tube) that slowly releases a medicine called sirolimus to keep your heart artery open after angioplasty. It is designed for people with narrowing in their heart arteries who need a stent.
Seoul, SeoulAges 19 years+ - NCT06089616Recruiting
Long-term safety study of palovarotene in FOP patients
This study tracks the long-term safety and how well palovarotene works in people with FOP who are already taking it as part of their regular care. By joining, you help doctors learn more about the medicine over time.
San Francisco, CaliforniaAges 8 years+ - NCT05564026Recruiting
Study of DNA patterns in childhood germ cell tumors
This study looks at “molecular” (DNA-related) features of germ cell tumors in children and teens. It also follows patients over time, which can help researchers understand tumor patterns and improve future care.
Minneapolis, MinnesotaAges Any age - NCT06096740Recruiting
Talking therapy for PTSD and its effects on the brain
This study looks at how a specific type of talk therapy affects the way your brain processes rewards. You'd join a group that either starts therapy right away or waits a bit before starting. Your brain activity will be scanned with an MRI to see changes.
Austin, TexasAges 18–65
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Common questions
- Are there clinical trials for effectiveness?
- Yes. Clin2 currently lists 6,378 recruiting effectiveness studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a effectiveness trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a effectiveness trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.