Clinical trials
Effectiveness clinical trials
Below are recruiting effectiveness clinical trials, each written for real people, not researchers. We’re tracking 6,378 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06078683Recruiting
Ketone drink for exercise and heart health in type 2 diabetes
This study tests whether a special ketone drink can improve exercise ability and heart function in people with type 2 diabetes. Participants will have two treadmill exercise tests and heart MRI scans to see how the drink affects their performance and cardiac efficiency.
Columbus, OhioAges 18–80 - NCT06061770Recruiting
Comparing two exercise programs for chronic stroke patients
This trial compares a supervised exercise program in a special facility with a self-guided exercise program at home. It aims to see which is more effective for improving walking and daily activity in people who had a stroke more than 6 months ago.
Marseille, Bouches du RhôneAges 18 years+ - NCT06073704Recruiting
Light therapy for gum disease in people with obesity
This study tests whether adding a special light-activated cleaning (antimicrobial photodynamic therapy) to standard gum disease treatment can help people with obesity who have gum disease. It aims to see if this extra step improves gum health more than standard treatment alone.
Bauru, São PauloAges 18–70 - NCT06070649RecruitingPhase 1
DMT for Alcohol Use Disorder
This trial tests whether a single dose of DMT, a psychedelic, can help people with alcohol use disorder. It's a small early-phase study to see if the treatment is safe and promising.
New Haven, ConnecticutAges 21–65 - NCT06058169Recruiting
Home vibration therapy for arthritis knee pain
This study tests if doing whole-body vibration exercises at home can help reduce knee pain from arthritis. You stand on a gently vibrating platform for short periods over several weeks.
Augusta, GeorgiaAges 40–75 - NCT06076252Enrolling by invitation
Comparing two surgical methods for pancreatic cancer
This trial compares a modified surgical technique to the standard one for removing pancreatic tumors. It aims to see if the new method lowers the risk of a leak from the pancreas after surgery.
Zhanjiang, GuangdongAges 18–75 - NCT06077240Recruiting
E-cigarettes vs pouches for quitting smoking
This study compares the effects of e-cigarettes and nicotine pouches on smoking habits and addiction. The goal is to see which method helps people smoke less and reduces their dependence on cigarettes.
New Haven, ConnecticutAges 21 years+ - NCT06059664RecruitingPhase 2
Finerenone for kidney transplant recipients: the EFFEKTOR study
This study tests whether a medicine called finerenone can help protect kidney transplants from further damage. People who have had a kidney transplant and have protein in their urine may benefit from this treatment.
Chapel Hill, North CarolinaAges 18 years+ - NCT06076304RecruitingPhase 4
Comparing treatments for acute sinusitis
This trial tests whether nasal steroids, nasal irrigation, or oral antibiotics work best for acute sinusitis. It may help if you have ongoing sinus symptoms or a 'double-sickening' pattern after a cold.
Los Angeles, CaliforniaAges 18–75 - NCT06058585RecruitingPhase 3
Testing new treatments for chronic kidney disease
This study compares two experimental treatments—one that reduces protein in urine and another that may help control blood sugar and weight—for people with chronic kidney disease. It aims to find safer, more effective ways to slow kidney damage.
Garran, Australian Capital TerritoryAges 18 years+ - NCT04150614RecruitingPhase 4
Granisetron skin patch versus ondansetron for transplant nausea
This study compares a granisetron skin patch to ondansetron tablets/medicine to see which works better to prevent nausea and vomiting around stem cell transplant. It may help your care team choose the most effective anti-nausea option for transplant patients.
Chicago, IllinoisAges 18–75 - NCT06044935Recruiting
Nicotinamide riboside for fat burning and metabolism
This study tests whether a supplement called nicotinamide riboside (a form of vitamin B3) helps the body burn fat more efficiently during exercise. It may be a good option if you are overweight or have a specific type of diabetes (MODY2) and want to see if a natural supplement can boost your metabolism.
Bethesda, MarylandAges 18–65 - NCT06032923RecruitingPhase 1/Phase 2
Does vitamin B3 boost help lupus symptoms?
This study tests whether a form of vitamin B3, called nicotinamide riboside, can improve immune function and reduce inflammation in women with mild to moderate lupus. It may help understand if boosting NAD+ levels offers a new way to manage the disease.
Bethesda, MarylandAges 18–120 - NCT06055452RecruitingPhase 4
SGLT2 Inhibitors for Pre-Heart Failure with Hypertension
This trial tests if a medicine (SGLT2 inhibitor) given to people with high blood pressure and early signs of heart stress can help prevent heart failure. You may join if your blood pressure is controlled but tests show your heart is beginning to struggle.
Beijing, Beijing MunicipalityAges 18 years+ - NCT05371886Recruiting
Testing how morphine (with or without midazolam) behaves in NICU babies
This study measures how morphine works in very young babies, and whether adding midazolam changes how the medicines behave and affect the body. It may help doctors better choose and dose pain/sedation medicines for babies in intensive care.
BrestAges 5 months–10 months - NCT06041789RecruitingPhase 2
Does a memory medication affect bone health?
This study looks at whether a common memory medication (called donepezil) can also help keep your bones strong. If you have memory problems and are willing to start this medication, you might be able to join.
Durham, North CarolinaAges 50 years+ - NCT06032208Recruiting
Study on expanded dialysis for symptom relief
This study tests whether a different type of dialysis, called expanded dialysis, can improve symptoms like fatigue or discomfort. It is for people who have been on regular hemodialysis for at least 3 months.
Winnipeg, ManitobaAges 18 years+ - NCT06042517Recruiting
Ultrasound Nerve Stimulation for Diabetes
This study tests whether focused ultrasound can help people with type 2 diabetes by gently stimulating nerves. It may offer a new way to improve glucose control without medication.
New Haven, ConnecticutAges 18–80 - NCT06041685Recruiting
Warming for artery catheter in children under 2
This trial tests if warming the skin before placing an artery line helps children having heart surgery. It may make the procedure easier and more comfortable.
Yangsan, Gyeongsangnam-doAges Up to 2 years - NCT06041958Recruiting
Shock Wave and Pulsed Field Therapy for Lymphedema
This trial tests two non-invasive therapies—shock wave therapy and pulsed electromagnetic field therapy—to see if they can reduce arm or leg swelling (lymphedema) caused by cancer treatment. It's for people who are at least 20 and have had breast or gynecologic cancer.
Kaohsiung CityAges 20–80 - NCT06039488Enrolling by invitation
Cancer exercise program for adults
This study tests if a supervised exercise program helps adults with cancer feel better and stay active. You would come to the clinic a few times a week for guided workouts.
Columbia, South CarolinaAges 18 years+ - NCT06039930Recruiting
Tele-PROTECT therapy for depression and elder abuse help
This study tests a phone or video therapy program for older adults who are experiencing both depression and elder abuse. The therapy is designed to be done from home and aims to help you feel safer and less depressed.
New York, New YorkAges 60 years+ - NCT06051123Recruiting
Probiotics for ALS and related disorders
This trial tests whether probiotics (healthy bacteria) can help people with ALS. You'll take a probiotic or placebo daily for several months, and researchers will track your symptoms and gut health.
Fredericton, New BrunswickAges 18 years+ - NCT06034821Enrolling by invitationPhase 4
ECT vs. ketamine for suicidal depression in adults
This trial compares two treatments—ECT (electroconvulsive therapy, which uses electrical stimulation) and ketamine (a medicine given as a shot)—to see which works better for quickly reducing suicidal depression. It is for adults who are in a severe depressive episode with active suicidal thoughts.
San Francisco, CaliforniaAges 18–90
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Common questions
- Are there clinical trials for effectiveness?
- Yes. Clin2 currently lists 6,378 recruiting effectiveness studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a effectiveness trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a effectiveness trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.