Clinical trials
Effectiveness clinical trials
Below are recruiting effectiveness clinical trials, each written for real people, not researchers. We’re tracking 6,863 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT05826743Recruiting
Check a new alternative to ileostomy after bowel surgery
This trial tests whether a device called COLO-BT can be a safer, effective alternative to an ileostomy (a temporary or longer-term opening from the intestine to the skin). It’s for certain adults having a bowel connection low in the pelvis, where leak risk matters.
Buffalo, New YorkAges 19–80 - NCT07290504Recruiting
Tourniquet Release Methods for People with High Blood Pressure
This study tests two ways of releasing a tourniquet (a pressure cuff) after arm surgery to see which keeps blood pressure more stable in people with controlled high blood pressure. If you are having arm or hand surgery with a tourniquet, you may be able to join.
CairoAges 18–65 - NCT06296017Recruiting
Comparing nonsurgical treatments for trigger finger
This study compares nonsurgical treatments (like exercises, splints, or injections) for trigger finger. It aims to find which conservative approach works best for mild cases without surgery.
AnkaraAges 18–65 - NCT07678437Enrolling by invitation
Blood flow restriction exercise for strength after spinal cord injury
This trial tests whether controlled exercise with blood flow restriction (a gentle technique) can help you regain strength after an incomplete spinal cord injury. It is for people currently receiving care at Quality Living, Inc.
Omaha, NebraskaAges 19–75 - NCT07614867Recruiting
Group therapy for emotion control in adults with ADHD
This study tests whether group-based cognitive behavioral therapy (a type of talk therapy) can help adults with ADHD who struggle to manage their emotions. You would attend sessions with others facing similar challenges to learn practical emotion-regulation skills.
StockholmAges 18 years+ - NCT07420738Recruiting
Brain protection during heart bypass surgery study
This trial studies whether different circulatory support techniques during coronary artery bypass surgery affect blood flow to the brain. It may help find ways to protect brain function during the procedure.
IstanbulAges 18–75 - NCT06180837Recruiting
Can longer sleep improve heart health in overweight adults?
This study tests if getting more sleep (7+ hours) can lower certain fats in the blood called ceramides, which are linked to heart disease risk. It's for overweight adults who currently sleep less than 6.5 hours a night.
Salt Lake City, UtahAges 18–45 - NCT07552896Recruiting
Screen Time and Recovery Confusion After Children's Surgery
This study looks at whether the amount of time children spend on screens (phones, tablets, TV) before surgery affects confusion and agitation as they wake up from anesthesia. Researchers want to understand this connection to help reduce distressing wake-up experiences.
Istanbul, IstanbulAges 2–11 - NCT07476092Recruiting
Digital games for thinking and visual skills
This study tests whether playing specially designed digital games can improve visual and thinking skills in young adults with mild to moderate intellectual disabilities. It is run by Koç University and takes place at EÇADEM, a center that supports people with special needs.
Istanbul, TürkiyeAges 18–35 - NCT06379789RecruitingPhase 1/Phase 2
Gene therapy for severe hemophilia B
This trial tests a new gene therapy (REGV131-LNP1265) that aims to let your body produce its own factor IX, reducing or stopping the need for regular infusions. It is for children and adults with severe hemophilia B who are already using factor IX replacement therapy.
Los Angeles, CaliforniaAges 2 years+ - NCT07744022Recruiting
Exercise comparison for children with obesity
This study compares two types of exercise programs — progressive neuromuscular stabilization exercises versus aerobic exercises — to see which one better improves body composition and balance in children with obesity. It aims to find a fun, effective way to help kids move better and feel healthier.
IstanbulAges 12–18 - NCT07745062RecruitingPhase 4
Comparing two eye drops for mild to moderate dry eye
This study tests two types of preservative-free eye drops to see which is more effective for people with mild to moderate dry eye disease. You will use one of the drops as directed, and the study will monitor your symptoms and eye health over time.
La Jolla, CaliforniaAges 18 years+ - NCT07667556Recruiting
Frozen shoulder treatment: gentle movement, pain education, and core exercises
This study tests whether a combination of gentle joint movement techniques, pain education, and core-strengthening exercises can help people with frozen shoulder move better and feel less pain. It may be a good fit if you have been diagnosed with frozen shoulder and are looking for a drug-free treatment option.
IstanbulAges 18–65 - NCT07656415RecruitingPhase 3
Study of mitapivat for sickle cell disease patients who need blood transfusions
This study tests whether a daily pill called mitapivat can reduce the number of blood transfusions you need. It is for people with sickle cell disease who have had at least one transfusion in the past year and are not on regular transfusion therapy.
Indianapolis, IndianaAges 12 years+ - NCT03866382RecruitingPhase 2
Immunotherapy plus a targeted drug for rare genitourinary tumors
This Phase 2 study tests whether nivolumab and ipilimumab (immunotherapy drugs) plus cabozantinib (a targeted anti-cancer drug) can shrink or control rare cancers of the urinary/reproductive system that have spread. It may help by boosting the immune system and blocking cancer growth signals at the same time.
Birmingham, AlabamaAges 18 years+ - NCT07602270Recruiting
How a Ketogenic Diet Affects Alcohol in Your Body
This study tests whether eating a ketogenic diet (very low carb, high fat) changes how your body processes alcohol. Researchers will have you follow a special diet and then measure your body's response to controlled amounts of alcohol in a lab setting.
Philadelphia, PennsylvaniaAges 21–50 - NCT07245030Recruiting
Virtual reality vs show-do for dental anxiety in kids with hearing loss
This trial tests whether virtual reality or a show-do method works better to reduce dental anxiety in children who have moderate to severe hearing loss. If your child needs a dental cleaning, this could help make the visit less stressful.
Giza, Giza GovernorateAges 6–12 - NCT07518953Recruiting
Can Music Help With Pain During a Nail Biopsy?
This study tests whether listening to music during a nail biopsy—a small procedure to remove a sample of nail tissue—can reduce pain and anxiety. You would listen to music during the procedure and answer a few questions about how you felt.
New York, New YorkAges 18 years+ - NCT06788249RecruitingEarly Phase 1
Ketamine for treatment-resistant depression brain study
This trial tests whether a single dose of ketamine can quickly improve depression by studying brain chemical changes using MRI. It's for people with treatment-resistant depression who haven't used ketamine before.
Philadelphia, PennsylvaniaAges 25–65 - NCT07069738Recruiting
New pacemaker vs standard cardiac therapy for heart failure
This study tests a newer type of pacemaker that paces the heart's left bundle branch area, compared to the usual cardiac resynchronization therapy. It is for people with heart failure who need a combined pacemaker-defibrillator (CRT-D) and have a specific heart rhythm pattern (left bundle branch block) with reduced pumping strength.
Huntsville, AlabamaAges 18 years+ - NCT06317259Recruiting
Studying how breathwork affects the body
This trial tests if doing specific breathwork exercises can have benefits for your health. You will follow a breathing program to see how it affects your body and mind.
La Jolla, CaliforniaAges 18–45 - NCT07743073Recruiting
Ceylon cinnamon for diabetic nerve pain
This study tests whether taking Ceylon cinnamon daily can help lower blood sugar, improve cholesterol, and reduce nerve pain in adults with type 2 diabetes and painful diabetic peripheral neuropathy. If you qualify, you might get a natural supplement that could ease your symptoms.
AmmanAges 18 years+ - NCT07134686Recruiting
Combined lung and ear-nose-throat care for asthma and sinusitis
This trial tests if seeing a lung specialist and an ear-nose-throat doctor together in one visit helps people with asthma and chronic sinusitis (with nasal polyps) feel better than seeing each specialist separately. You may qualify if your asthma or sinusitis is not well-controlled and you've used steroid pills in the past year.
MarseilleAges 18 years+ - NCT07743294Recruiting
Exercise before breast cancer surgery to reduce arm swelling
This trial tests whether doing specific exercises before breast cancer surgery helps reduce arm swelling (lymphedema) after surgery, and improves quality of life and care needs. You would participate in a supervised exercise program before your surgery and then follow up after.
TaipeiAges 20 years+
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Common questions
- Are there clinical trials for effectiveness?
- Yes. Clin2 currently lists 6,863 recruiting effectiveness studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a effectiveness trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a effectiveness trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.