Clinical trials
Efficacy and Safety clinical trials
Below are recruiting efficacy and safety clinical trials, each written for real people, not researchers. We’re tracking 2,733 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06220773RecruitingPhase 3
combination treatment for type 2 diabetes and high blood pressure
This study tests two new combination medicines for people who have both type 2 diabetes and high blood pressure. It looks at how well they work and how safe they are. Participants stop their current diabetes and blood pressure drugs during the trial, except for the diabetes drug metformin.
Jakarta, DKI JakartaAges 19 years+ - NCT07265947RecruitingPhase 2
Dabogratinib for low grade upper tract urothelial carcinoma
This trial tests a new pill, dabogratinib, for people with low grade cancer in the upper urinary tract (the tubes that carry urine from the kidneys to the bladder). It may help shrink or control the cancer without needing surgery to remove the kidney.
Loma Linda, CaliforniaAges 18 years+ - NCT06819878RecruitingPhase 3
Afimkibart for moderate to severe Crohn's disease
This study tests an experimental drug called afimkibart for people with moderate to severe Crohn's disease who haven't responded well to other treatments. The goal is to see if the drug can help control symptoms and reduce inflammation over time.
Dothan, AlabamaAges 16–80 - NCT07378644RecruitingPhase 2/Phase 3
Testing SKY-0515 for Huntington's disease
This trial tests a new drug called SKY-0515 in people with Huntington's disease. The goal is to see if it can safely improve symptoms or slow the disease down.
Englewood, ColoradoAges 25 years+ - NCT06126224RecruitingPhase 3
Testing KarXT for Alzheimer's-related psychosis
This clinical trial tests an investigational oral medication called KarXT for treating psychosis (hallucinations or delusions) in people with Alzheimer's disease. The study aims to see if the drug can safely reduce these symptoms.
Chandler, ArizonaAges 55–90 - NCT07162571Enrolling by invitationPhase 1/Phase 2
Engineered immune cells for advanced leukemia or lymphoma
This study tests a new type of immune therapy called CAR-T cells, which are made from your own blood cells to find and attack cancer. It is for adults with leukemia or lymphoma that has come back or is hard to treat.
MinskAges 18 years+ - NCT07185009RecruitingPhase 3
Testing duvakitug for long-term ulcerative colitis control
This study tests the long-term safety and effectiveness of an experimental drug called duvakitug in people with moderate to severe ulcerative colitis. It is for those who have already responded well to treatment in a previous study and need ongoing care.
Tucson, ArizonaAges 16–80 - NCT07423975RecruitingPhase 2
Testing anakinra to improve recovery after stroke treatment
This study tests a medicine called anakinra (usually used for inflammation) to see if it helps improve recovery after a stroke caused by a blocked artery that was successfully opened with a procedure. It aims to reduce brain damage and improve outcomes for patients who still have significant symptoms after treatment.
Beijing, Beijing MunicipalityAges 18–80 - NCT06920004RecruitingPhase 3
Testing empasiprubart vs IVIg for chronic CIDP
This study tests an investigational drug called empasiprubart against standard IVIg in adults with CIDP. The goal is to see if it is safer and more effective for people who still have symptoms despite IVIg therapy.
Birmingham, AlabamaAges 18 years+ - NCT07629843Recruiting
Laser treatment for varicose veins
This study looks at how well laser treatment works for varicose veins and how satisfied patients are with it. It aims to see if this treatment is safe and effective for people with common or recurring varicose veins.
ParisAges 18 years+ - NCT07091630RecruitingPhase 3
A study of empasiprubart for chronic inflammatory demyelinating polyneuropathy (CIDP)
This study tests a new medicine called Empasiprubart for adults with ongoing CIDP. It aims to see if fewer symptoms return and if it can replace current treatments.
Birmingham, AlabamaAges 18 years+ - NCT07531043RecruitingPhase 3
Eye drops for redness in adults
This study tests a new eye drop called FID 123472 to see how well it reduces redness in adults. If you have persistent eye redness and have used redness relief drops before, this trial might help you find a longer-lasting solution.
Los Angeles, CaliforniaAges 18 years+ - NCT07518810RecruitingPhase 2/Phase 3
Testing butylphthalide for multiple system atrophy
This study tests whether a drug called butylphthalide can safely help people with multiple system atrophy (MSA), a rare brain disorder that affects movement and automatic body functions like blood pressure. Participating may help slow the progression of symptoms and improve quality of life.
Nanning, GuangxiAges 30–80 - NCT07570316RecruitingPhase 3
Testing efgartigimod for Graves' disease hyperthyroidism
This study tests whether efgartigimod, an injectable medication given under the skin, can help control overactive thyroid (Graves' disease) in adults already taking methimazole or carbimazole. The goal is to see if it reduces thyroid antibodies and improves thyroid hormone levels.
Orange, CaliforniaAges 18 years+ - NCT07878572Enrolling by invitationEarly Phase 1
Follow-up study of gene therapy in the other eye
This study looks at the safety and effectiveness of giving the gene therapy treatment to your other eye, after you've already had it in one eye and been followed for a year. It may help improve vision in the untreated eye.
Beijing, Beijing MunicipalityAges 8–45 - NCT07596849RecruitingPhase 3
Testing a New Injection for Graves' Disease
This study tests efgartigimod, a new medicine given by injection under the skin, to see if it can help control Graves' disease (an overactive thyroid condition). The goal is to reduce the need for other thyroid medications or help people stop taking them.
Aalst, Oost-VlassAges 18 years+ - NCT07676565Recruiting
Adding new drugs to insulin for type 1 diabetes
This study tests whether adding certain diabetes pills (GLP-1 receptor agonists or SGLT inhibitors) to insulin is safe and helpful for adults with type 1 diabetes. Doctors will check your glucose monitor data to see how well this works.
Newport Beach, CaliforniaAges 18 years+ - NCT07225569RecruitingPhase 2
Study of a new drug for moderate to severe hidradenitis suppurativa
This trial tests a new medication, SAR445399, for people with moderate to severe hidradenitis suppurativa (HS) who haven't improved with oral antibiotics. It aims to see if the drug safely reduces skin bumps and abscesses.
Scottsdale, ArizonaAges 18 years+ - NCT07554521RecruitingPhase 2
Tislelizumab Plus Chemotherapy for Advanced Stomach or Esophageal Cancer
This study tests a combination of two drugs—tislelizumab (an immunotherapy) and chemotherapy—to treat advanced stomach, gastroesophageal junction, or esophageal cancer that cannot be surgically removed. The trial focuses on recruiting patients from racial and ethnic minority communities to ensure the treatment is studied in diverse populations.
Bullhead City, ArizonaAges 18 years+ - NCT07610395RecruitingPhase 2
Testing an oral drug for cold virus in COPD patients
This trial tests an oral medication (VPV) to see if it can safely treat rhinovirus (a common cold virus) in people with COPD. The goal is to help you recover faster and prevent serious COPD flare-ups.
Mobile, AlabamaAges 40–85 - NCT07294170Recruiting
Testing Multiple Treatments for Myasthenia Gravis
This trial tests multiple treatment combinations for people with myasthenia gravis (MG), a condition that causes muscle weakness. It aims to find safer and more effective options by comparing different therapies.
Carlsbad, CaliforniaAges 18 years+ - NCT07620392RecruitingPhase 2
Long-Term Safety Study of Afimkibart for Rheumatoid Arthritis
This is a follow-up study for people who already completed a previous trial testing afimkibart (an experimental drug) for rheumatoid arthritis. It checks whether the drug continues to work safely and effectively over a longer period.
Tamarac, FloridaAges 18 years+ - NCT07137598RecruitingPhase 2
A study of RO7790121 for moderate to severe rheumatoid arthritis
This study tests a new drug, RO7790121, for people with rheumatoid arthritis (RA) who have not gotten better with or could not tolerate common treatments like TNF inhibitors or JAK inhibitors. It aims to see if the drug is safe and can help reduce joint pain and swelling.
Avondale, ArizonaAges 18 years+ - NCT07159763RecruitingPhase 3
Study of a new medicine to prevent flu
This study tests a new type of flu prevention medicine (called a monoclonal antibody) given as an injection. It is for people at higher risk of getting the flu, including those with certain health conditions or weakened immune systems.
Anniston, AlabamaAges 12 years+
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Common questions
- Are there clinical trials for efficacy and safety?
- Yes. Clin2 currently lists 2,733 recruiting efficacy and safety studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a efficacy and safety trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a efficacy and safety trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.