Clinical trials
Efficacy and Safety clinical trials
Below are recruiting efficacy and safety clinical trials, each written for real people, not researchers. We’re tracking 2,807 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07412132RecruitingPhase 3
Testing lacosamide for hard-to-treat bipolar depression
This study tests if a medication called lacosamide can help people with bipolar depression that has not improved with at least two other treatments. It's for those with moderate to severe depression in bipolar I or II.
São Paulo, São PauloAges 18–65 - NCT07420985RecruitingPhase 2
Ingavirin forte for flu and other viral infections
This trial tests different doses of Ingavirin Forte capsules for treating influenza and other respiratory viruses. It may help people with fever, cough, sore throat, and body aches who have been sick less than 48 hours.
IvanovoAges 18–65 - NCT07421297RecruitingPhase 3
Study of SYH2053 for high cholesterol in Chinese adults
This trial tests a new medication called SYH2053 for people with high cholesterol or mixed high cholesterol and triglycerides. If you have high LDL cholesterol and are not taking strong cholesterol medicines, you may be able to join. The study will see if this drug is safe and works well.
Beijing, Beijing MunicipalityAges 18 years+ - NCT07432867RecruitingPhase 1/Phase 2
Gene therapy for severe sickle cell disease in teens and adults
This trial tests a new gene therapy for sickle cell disease. It uses your own blood stem cells (collected from bone marrow) that are modified in a lab to help produce healthy red blood cells, then given back to you after a short chemotherapy. The goal is to reduce or stop severe complications like pain crises and lung problems.
Paris, Île-de-France RegionAges 12–35 - NCT07453862RecruitingPhase 1
New drug for restless legs syndrome: efficacy and safety study
This trial tests a new drug (a calcium channel modulator) to see how well it works and how safe it is for people with moderate to severe restless legs syndrome (RLS). It may offer a new treatment option for those with typical or variant RLS.
Beijing, Beijing MunicipalityAges 18–75 - NCT07478744RecruitingPhase 2
Study for generalized anxiety disorder with SYT-510
This trial tests a new medicine called SYT-510 for adults with generalized anxiety disorder who are not currently taking medication. It aims to see if the drug reduces anxiety and is safe.
LondonAges 18–55 - NCT07467707RecruitingPhase 3
Chikungunya vaccine trial for teens and adults
This trial tests an experimental chikungunya vaccine (made from a virus-like particle) to see if it prevents the disease. It is for healthy teens and adults who have not had chikungunya before.
Cebu City, CebuAges 12 years+ - NCT07548697RecruitingEarly Phase 1
Safety study of CT1182 for relapsed B-cell lymphoma
This early-stage trial tests a new drug called CT1182 for B-cell non-Hodgkin lymphoma that has come back or stopped responding to prior treatment. The study will measure how safe the drug is, how well it works, and how your body processes it.
Wuhan, HubeiAges 18–75 - NCT07582432RecruitingPhase 3
Gamunex for Blood Cancer Patients With Low Antibodies
This trial tests whether Gamunex, an antibody replacement therapy, helps patients with chronic lymphocytic leukemia, multiple myeloma, or non-Hodgkin lymphoma who have low immunoglobulin (antibody) levels. The treatment may reduce infections and improve how well the body fights disease.
St. Petersburg, FloridaAges 18 years+ - NCT07588438RecruitingPhase 4
Tirzepatide effectiveness and safety for diabetes and weight loss in Paraguay
This study tests how well and safely tirzepatide (a new injectable medication) works in real-world conditions for people with type 2 diabetes or obesity in Paraguay. The medication helps lower blood sugar and reduce weight.
AsunciónAges 18–70 - NCT07594158RecruitingPhase 3
ONO-2017 for Seizures in Japanese Children and Teens
This study tests a new seizure medication called ONO-2017 in Japanese children and teenagers (ages 2–17) who have a specific type of seizure called POS that hasn't been controlled by current medicines. The goal is to see if this new drug is safe and helps reduce these seizures.
FukuokaAges 2–17 - NCT07595003RecruitingPhase 3
Testing a new medicine for gallbladder pain and discomfort
This study tests whether a medicine called 4-MUST can safely reduce pain and digestive symptoms caused by chronic gallbladder problems. You'll take tablets for several weeks while researchers track how well the medicine works and any side effects.
MoscowAges 18–70 - NCT07608432RecruitingPhase 3
Testing a New DMD Treatment Given Every 4 Weeks
This study tests whether a new medicine called zeleciment rostudirsen can help ambulatory (walking) males with Duchenne muscular dystrophy (DMD). The medicine is given as an intravenous infusion (through a vein) every 4 weeks and works by helping the body produce a protective muscle protein.
Hillsborough, North CarolinaAges 4–18 - NCT07608770RecruitingPhase 2
CBL-514 injection to reduce belly fat
This study tests whether CBL-514, an injection given under the skin, can safely reduce stubborn belly fat in people with normal to slightly elevated weight. Researchers will measure changes in abdominal fat using imaging and patient assessments.
South Yarra, VictoriaAges 18 years+ - NCT07614958RecruitingPhase 3
Testing a new cholesterol medicine against bempedoic acid
This study compares two new medicines—obicetrapib and bempedoic acid—to see which one better lowers cholesterol in people whose cholesterol remains high despite taking standard medications. If your cholesterol isn't controlled well enough with current drugs, this trial may help you access an experimental treatment.
Stockton-on-TeesAges 18 years+ - NCT07640893RecruitingPhase 2
Testing a new injection for von Willebrand disease
This study tests whether SR604, a new injection given under the skin, can reduce bleeding episodes in people with von Willebrand disease (a condition where blood doesn't clot properly). The trial will measure how well it works, how safe it is, and how your body processes it.
ChangshaAges 18–65 - NCT07660354Recruiting
Head lice treatment study comparing a new product to Nix
This trial tests a new head lice product (X92001483) to see how safe and effective it is compared to the standard treatment Nix. It looks at both getting rid of lice and preventing them from coming back.
Maitland, FloridaAges 1 year+ - NCT06945640Enrolling by invitation
Testing a 3D imaging system for robot kidney surgery
This study tests a new 3D imaging system (RUS NE) to help surgeons perform robot-assisted partial nephrectomy more safely and effectively. If you have a small to medium-sized kidney tumor and are already scheduled for this surgery, the researchers want to compare your outcomes to people who had the standard procedure.
SeoulAges 20–80 - NCT06840652Enrolling by invitation
Baclofen for alcohol withdrawal in liver disease
This trial tests if baclofen, a medicine for alcohol dependence, is safe and works for people with chronic liver disease who are actively drinking. It may help you stop drinking alcohol safely.
Sabadell, BarcelonaAges 18–75 - NCT05664737RecruitingPhase 2
Luspatercept for adults with alpha thalassemia
This study tests a medicine called luspatercept to see if it can help people with alpha thalassemia need fewer blood transfusions. It is for adults and some teens with this condition.
Halifax, Nova ScotiaAges 12 years+ - NCT07253896RecruitingPhase 2
AK104 with chemo and targeted therapy for advanced colon cancer
This trial tests a new drug called AK104 combined with standard chemotherapy and either cetuximab or bevacizumab for people with metastatic colorectal cancer that cannot be surgically removed. It is for those who have had only one prior line of treatment and whose tumors are not MSI-H or have a BRAF mutation.
Hangzhou, ZhejiangAges 18–75 - NCT06738160RecruitingPhase 2
Combination therapy for bone metastases from advanced lung cancer
This trial tests adding a new drug (narlumosbart) and targeted radiation to standard chemotherapy and immunotherapy for people with advanced non-small cell lung cancer that has spread to the bones. The goal is to see if this combination works better than standard treatment alone.
Shanghai, Shanghai MunicipalityAges 18–80 - NCT06573489RecruitingPhase 4
Fospropofol for laparoscopic surgery safety study
This trial tests a sedative called fospropofol during laparoscopic abdominal surgery. It aims to see if it's safe and effective for adults with longer operations.
Wuhan, HubeiAges 18–65 - NCT05113017Recruiting
Radiation after surgery for early lung cancer you can’t remove
This trial studies whether a focused form of radiation called SBRT can safely treat remaining lung cancer nodules after surgery. It may help people whose leftover tumor spots can’t be removed by more surgery, aiming to control the cancer while limiting side effects.
Changsha, HunanAges 18–75
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Common questions
- Are there clinical trials for efficacy and safety?
- Yes. Clin2 currently lists 2,807 recruiting efficacy and safety studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a efficacy and safety trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a efficacy and safety trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.