Clinical trials
Efficacy and Safety clinical trials
Below are recruiting efficacy and safety clinical trials, each written for real people, not researchers. We’re tracking 2,733 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06546111RecruitingPhase 1/Phase 2
Diosmin and hesperidin for H. pylori infection
This trial tests whether a combination of two natural plant compounds, diosmin and hesperidin, can safely and effectively treat Helicobacter pylori (H. pylori) infection in people who have not been treated for it before. The goal is to see if this therapy offers a new option for clearing the bacteria.
Shibīn al KawmAges 18–75 - NCT07775924RecruitingPhase 2
New drug for moderate to severe lichen planus
This study tests a new medication for people with moderate to severe lichen planus that has not improved with topical treatments. The goal is to see if it reduces symptoms and improves quality of life.
Birmingham, AlabamaAges 18–99 - NCT07778836RecruitingPhase 3
Study of daily injections for Friedreich's ataxia
This study tests an investigational drug given as a daily injection to see if it can improve walking and balance in people with Friedreich's ataxia.
Tampa, FloridaAges 12–40 - NCT07782957RecruitingPhase 3
New shot for severe nasal polyps with ongoing sinus symptoms
This study tests an experimental medication called felcorekibart, given as an injection, to see if it reduces nasal polyps and improves sinus symptoms like congestion and loss of smell. It is for adults who have had nasal polyps for at least a year and have already tried standard treatments like steroid sprays or pills, or had surgery.
Sherman Oaks, CaliforniaAges 18 years+ - NCT07782827RecruitingPhase 3
Angel syndrome treatment study for children and adults
This study tests an experimental medicine for Angelman syndrome (AS), a genetic condition affecting the nervous system. The medicine is given by lumbar puncture and aims to improve symptoms.
Carrboro, North CarolinaAges 2–50 - NCT07782970RecruitingPhase 3
Treatment for chronic sinusitis with nasal polyps
This study tests a new medication (felcorekibart) to see if it reduces nasal polyps and symptoms like congestion and loss of smell. It may help people whose current treatments aren't enough.
Los Angeles, CaliforniaAges 18 years+ - NCT07780656RecruitingPhase 3
Felcorekibart for chronic obstructive pulmonary disease (COPD)
This study tests a new medicine, felcorekibart, to see if it can reduce COPD flare-ups better than a placebo after 52 weeks. It's designed for people with high eosinophils, a type of white blood cell linked to inflammation.
Miami, FloridaAges 40–80 - NCT07782996RecruitingPhase 3
Study of a new asthma drug for people with uncontrolled asthma
This study is testing whether an investigational drug called GSK5784283 can improve asthma control compared to a placebo. It is for people with uncontrolled asthma who are already on standard daily asthma medications.
Miami Lakes, FloridaAges 12–80 - NCT07780643RecruitingPhase 3
Asthma study for uncontrolled asthma on inhaled steroids
This study is testing an investigational medication for people with uncontrolled asthma. Participants must have moderate-to-severe asthma, be on appropriate maintenance therapy, and meet specific safety criteria.
Miami Lakes, FloridaAges 12–80 - NCT07780669RecruitingPhase 3
Study of a new drug for moderate to severe COPD in smokers
This study tests a new medication (GSK5784283) for people with moderate to severe COPD who have a certain type of inflammation (eosinophilic). Participants must be on standard inhaler therapy and have a history of smoking. The trial will compare the new drug to a placebo.
Doral, FloridaAges 40–80 - NCT07779564Recruiting
Electric flosser study for plaque and gum health
This study tests whether an electric flosser is better than a manual toothbrush for reducing plaque and gum inflammation. Participants will use the electric flosser for 30 days while having regular checkups. This could help you learn a new way to improve your oral health.
Fort Wayne, IndianaAges 18–70 - NCT07776262Recruiting
Freezing thyroid tumors and nodules
This trial tests a treatment that uses extreme cold to freeze and destroy small thyroid cancers and large benign nodules. It may be an option for people who cannot or do not want to have surgery.
Beijing, Beijing MunicipalityAges Any age - NCT07776821RecruitingPhase 4
Immunotherapy with chemoradiation for advanced cervical cancer
This trial tests a new drug called Enlonstobart, which helps the immune system fight cancer, given with standard chemotherapy and radiation for patients with locally advanced cervical cancer. The goal is to see if this combination is effective and safe.
TianjinAges 18–75 - NCT05654454RecruitingPhase 3
Bevacizumab plus chemotherapy vs Avastin for advanced lung cancer
This trial compares a combination of anti-angiogenics (bevacizumab) plus chemotherapy (paclitaxel and carboplatin) against Avastin-based treatment in people with advanced non-small cell lung cancer. It aims to find out whether the study treatment is safer and works better for shrinking tumors and improving outcomes.
ArkhangelskAges 18 years+ - NCT06556342Recruiting
Testing a new contrast agent for ovarian mass ultrasound
This trial is testing an investigational contrast agent (FRD001) to see if it improves ultrasound images of suspicious ovarian masses. The goal is to help doctors better tell if a mass is cancerous or not.
Wuhan, HubeiAges 18–75 - NCT06562920RecruitingPhase 2
Immunotherapy plus chemo and SBRT before surgery for limited-stage small cell lung cancer
This trial tests a combination of immunotherapy (adebrelimab), chemotherapy, and targeted radiation (SBRT) before surgery for people with limited-stage small cell lung cancer. The goal is to see if this approach can shrink tumors and improve outcomes before the main treatment.
Hangzhou, ZhejiangAges 18–75 - NCT06451146Recruiting
Orbital atherectomy for calcified heart blockages
This trial studies a procedure called orbital atherectomy to treat hardened calcium deposits in heart arteries. It aims to help people with moderately to severely calcified blockages.
Legnica, Lower Silesian VoivodeshipAges 18 years+ - NCT07769528Recruiting
Heart pump support for severe heart failure
This study tests a device that helps the heart pump blood when it is too weak to do so, even with medicine, after surgery, or while waiting for a transplant. It aims to see if it's safe and works well.
Beijing, Beijing MunicipalityAges 18 years+ - NCT07770867Recruiting
Smartphone app for teens with autism or social communication disorder
This trial tests a smartphone app called NDTx-03 that may help improve social skills in teens aged 10-18 with autism or social communication disorder. It involves using the app 5 times a week for 8 weeks.
DaeguAges 10–18 - NCT07771465RecruitingPhase 3
Long-term safety of danicamtiv for genetic dilated cardiomyopathy
This study checks the long-term safety and effectiveness of the drug danicamtiv in people with a genetic form of dilated cardiomyopathy, a condition where the heart muscle becomes weak and enlarged. If you've already completed the earlier DAN-301 study, this trial continues to monitor you while you keep taking the medication.
Birmingham, AlabamaAges 18 years+ - NCT07767903RecruitingPhase 3
Study of a new medicine for generalized anxiety disorder
This trial tests an investigational medication to see if it can reduce anxiety symptoms in adults with generalized anxiety disorder. Participants will receive the study drug and be monitored for safety and effectiveness.
Redlands, CaliforniaAges 18 years+ - NCT07775404RecruitingPhase 3
Weight loss medication for Asian adults with obesity or overweight
This study tests an investigational medication called elecoglipron for weight loss in Asian adults who are overweight or have obesity, with or without type 2 diabetes. It may help participants lose weight and improve health.
BaotouAges 18 years+ - NCT04014413Recruiting
Fecal transplant for gut and immune-related conditions
This trial studies whether fecal microbiota transplantation (FMT)—a medical procedure using stool from a screened donor to restore gut bacteria—can improve safety and outcomes for people with certain bowel, immune, and metabolic conditions. It may help if your symptoms are thought to be related to an unhealthy gut microbiome, though eligibility is broad and depends on specific safety factors.
Hong Kong, ShatinAges Any age - NCT06316960RecruitingPhase 2
Avapritinib for children with relapsed or resistant CBF-AML and KIT mutation
This trial tests a targeted drug called avapritinib in children and teens with a specific type of leukemia (CBF-AML) that has a KIT gene change and has come back or not responded to treatment. The goal is to see if avapritinib is safe and effective for these patients.
Hefei, AnhuiAges Up to 18 years
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Common questions
- Are there clinical trials for efficacy and safety?
- Yes. Clin2 currently lists 2,733 recruiting efficacy and safety studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a efficacy and safety trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a efficacy and safety trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.