Clinical trials
End Stage Kidney Disease clinical trials
Below are recruiting end stage kidney disease clinical trials, each written for real people, not researchers. We’re tracking 141 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06755372Recruiting
TLR-4 in gum disease patients with kidney failure
This study looks at a specific immune marker (TLR-4) in people with gum disease, comparing those who also have end-stage kidney disease (on dialysis) to those who are otherwise healthy. The goal is to understand how gum disease might be different when kidney failure is also present.
Al Fayyum, Faiyum GovernorateAges 30–60 - NCT06842927Enrolling by invitation
A tool to measure how well peritoneal dialysis works
This study is testing a new computer tool that helps doctors see how well peritoneal dialysis (a type of kidney treatment done at home) removes waste from your body. It may help make your dialysis more effective.
TuenmenAges 18 years+ - NCT06314503Recruiting
Safety study of a new peritoneal dialysis device for kidney patients
This trial tests a new device called WEAKID for people on peritoneal dialysis. It aims to see if the device is safe to use. Participants must have been on PD for at least 3 months and have no recent infections or catheter problems.
Modena, ModenaAges 18 years+ - NCT06741072RecruitingPhase 1
Vaccine to prevent EBV-related cancer in transplant patients
This trial tests a vaccine (OSU-2131) that may help prevent cancers caused by the Epstein-Barr virus in people waiting for an organ transplant. The vaccine is designed to train your immune system to fight the virus.
Columbus, OhioAges 18–65 - NCT06712654RecruitingPhase 2
Testing AP306 for high phosphate in dialysis patients
This trial tests a new medication called AP306 for people on hemodialysis who have high blood phosphate. It aims to see if the drug is safe, tolerable, and helps lower phosphate levels.
Huntsville, AlabamaAges 18 years+ - NCT06660277Recruiting
Dialysis with expanded solute removal study
This trial tests a special dialysis filter (Elisio HX) that removes more waste products from the blood. It aims to see if this approach improves health outcomes for people on regular in-center hemodialysis.
London, OntarioAges 45 years+ - NCT06613568Recruiting
Testing a new home hemodialysis machine
This study tests a new home hemodialysis machine called the Moda-flx System. If you are on stable dialysis and have a care partner, you and your partner will learn how to use the machine at home, and the trial will see if it can safely and effectively replace your regular dialysis.
San Dimas, CaliforniaAges 18–80 - NCT05159466Recruiting
Transplant from HIV-positive donors to HIV-positive recipients
This trial studies whether it’s safe and effective for HIV-positive people to receive organ transplants from HIV-positive donors. It focuses on matching HIV treatment before and after transplant and checking for major complications.
Metairie, LouisianaAges 18 years+ - NCT06089473Recruiting
Home Exercise Program for Frail Kidney Transplant Candidates
This study tests whether a 12-week home exercise program (supervised by video calls) can help people who are frail feel stronger and healthier before a kidney transplant. You'll do exercises at home and connect with a trainer online.
Montreal, QuebecAges 18 years+ - NCT03803423Recruiting
Using social media to find kidney or liver donors
This study tests a way to spread information on how to register as a live organ donor using social media. You may be contacted to help identify potential live kidney or liver donors, if you fit the study’s basic requirements.
San Diego, CaliforniaAges 18 years+ - NCT06056102RecruitingPhase 1
CAR-T cell therapy to help highly sensitized kidney transplant patients
This trial tests whether a special immune cell treatment (CAR-T cells) can lower the antibodies that make it very hard for you to receive a kidney transplant. If it works, you might become eligible for a transplant sooner.
Boston, MassachusettsAges 18–65 - NCT06001827Recruiting
Study of a wrap to help new dialysis access points heal
This trial tests a special wrap placed around a new arm access point for dialysis (called an AV fistula) to see if it helps the access stay healthy and work better. It is for people who need a new AV fistula for kidney dialysis.
Bullhead City, ArizonaAges 18 years+ - NCT05931276RecruitingPhase 3
Beta blocker choice may improve heart outcomes on dialysis
This phase 3 study tests whether a specific beta blocker selection on hemodialysis can improve cardiovascular outcomes. It focuses on certain beta blockers commonly used through the VA pharmacy and compares them in a randomized way.
Long Beach, CaliforniaAges 18 years+ - NCT05738330Recruiting
Symptom reporting during hemodialysis care
This study looks at how well a new phone or computer system can help people on hemodialysis report their symptoms. It may improve symptom tracking so clinics can better understand and respond to what you feel during treatment.
Waltham, MassachusettsAges 18 years+ - NCT05525507RecruitingPhase 1
Test early immune-tolerance treatment for matched kidney transplant patients
This Phase 1 study tests a treatment plan given after a kidney transplant to help the immune system stay calm and reduce the risk of rejection. Participants must have a well-functioning kidney transplant from a closely matched living donor and meet health and safety requirements.
Los Angeles, CaliforniaAges 18 years+ - NCT05846581Recruiting
Dialysis graft registry for adults getting a new vascular graft
This registry follows adults with kidney failure who need a dialysis access connection in the arm using the GORE ACUSEAL graft. It helps track outcomes and safety over time while you receive standard dialysis care.
BielefeldAges 18 years+ - NCT05828823Recruiting
Two-times-a-week dialysis for new patients
This study tests whether starting dialysis at twice a week, instead of the usual three times, is safe and effective for people who still have some kidney function. If the kidneys still make urine and clear waste, being on dialysis less often may maintain that function longer.
Jacksonville, FloridaAges 18 years+ - NCT05715814RecruitingPhase 3
Test diabetes-pill type medicine on kidney dialysis safety
This Phase 3 trial studies the safety of an SGLT2 inhibitor (a diabetes medication that can affect kidney fluid handling) in people on peritoneal dialysis. The goal is to see how the treatment works in your type of dialysis and whether it causes any problems.
Toronto, OntarioAges 18 years+ - NCT05726526Recruiting
Phone app monitoring to help people with advanced kidney disease
This study tests a phone app (with check-ins on things like blood pressure and weight) to help prevent complications in people with advanced chronic kidney disease. You may be a good match if you’re high risk and can actively measure and share your health data with a kidney care team.
Winnipeg, ManitobaAges 18 years+ - NCT05642156Recruiting
Ultrafiltration versus usual dialysis in people on hemodialysis
This study compares a specific way of removing fluid during dialysis (isolated ultrafiltration) with conventional hemodialysis. It aims to see how each approach affects blood flow and fluid shifts in people with end-stage kidney disease.
GrazAges 18 years+ - NCT05485961RecruitingPhase 2/Phase 3
Clazakizumab for kidney failure patients on dialysis
This study tests an experimental drug called clazakizumab (CSL300) to see if it can reduce inflammation and lower the risk of heart problems in people with kidney failure who are on dialysis. It may help if you have diabetes or heart disease and have high inflammation levels.
Decatur, AlabamaAges 18 years+ - NCT05422534RecruitingPhase 3
CoQ10 plus exercise for people with advanced kidney disease
This trial tests whether a supplement called CoQ10, along with supervised exercise, can improve how the body uses energy in people on chronic dialysis. It may help with muscle function and overall health if your heart and dialysis situation are stable enough.
Sacramento, CaliforniaAges 18–75 - NCT04634916Recruiting
Check how a dialysis fistula device performs in real life
This study monitors how well the BD WavelinQ endoAVF device works after routine clinical use. It may help people who need a dialysis access fistula by sharing real-world safety and performance data.
La Jolla, CaliforniaAges 18 years+ - NCT04671771Recruiting
Testing a new graft for hemodialysis access in kidney failure
This study tests whether an “AV graft” implant works safely and well for people with end-stage kidney disease who need hemodialysis. It may help your dialysis access last and work better, compared with current expectations for AV grafts.
Phoenix, ArizonaAges 18–90
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Common questions
- Are there clinical trials for end stage kidney disease?
- Yes. Clin2 currently lists 141 recruiting end stage kidney disease studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a end stage kidney disease trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a end stage kidney disease trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.