Clinical trials
End Stage Kidney Disease clinical trials
Below are recruiting end stage kidney disease clinical trials, each written for real people, not researchers. We’re tracking 148 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06712654RecruitingPhase 2
Testing AP306 for high phosphate in dialysis patients
This trial tests a new medication called AP306 for people on hemodialysis who have high blood phosphate. It aims to see if the drug is safe, tolerable, and helps lower phosphate levels.
Huntsville, AlabamaAges 18 years+ - NCT05159466Recruiting
Transplant from HIV-positive donors to HIV-positive recipients
This trial studies whether it’s safe and effective for HIV-positive people to receive organ transplants from HIV-positive donors. It focuses on matching HIV treatment before and after transplant and checking for major complications.
Metairie, LouisianaAges 18 years+ - NCT05422534RecruitingPhase 3
CoQ10 plus exercise for people with advanced kidney disease
This trial tests whether a supplement called CoQ10, along with supervised exercise, can improve how the body uses energy in people on chronic dialysis. It may help with muscle function and overall health if your heart and dialysis situation are stable enough.
Sacramento, CaliforniaAges 18–75 - NCT05525507RecruitingPhase 1
Test early immune-tolerance treatment for matched kidney transplant patients
This Phase 1 study tests a treatment plan given after a kidney transplant to help the immune system stay calm and reduce the risk of rejection. Participants must have a well-functioning kidney transplant from a closely matched living donor and meet health and safety requirements.
Los Angeles, CaliforniaAges 18 years+ - NCT05642156Recruiting
Ultrafiltration versus usual dialysis in people on hemodialysis
This study compares a specific way of removing fluid during dialysis (isolated ultrafiltration) with conventional hemodialysis. It aims to see how each approach affects blood flow and fluid shifts in people with end-stage kidney disease.
GrazAges 18 years+ - NCT05715814RecruitingPhase 3
Test diabetes-pill type medicine on kidney dialysis safety
This Phase 3 trial studies the safety of an SGLT2 inhibitor (a diabetes medication that can affect kidney fluid handling) in people on peritoneal dialysis. The goal is to see how the treatment works in your type of dialysis and whether it causes any problems.
Toronto, OntarioAges 18 years+ - NCT05726526Recruiting
Phone app monitoring to help people with advanced kidney disease
This study tests a phone app (with check-ins on things like blood pressure and weight) to help prevent complications in people with advanced chronic kidney disease. You may be a good match if you’re high risk and can actively measure and share your health data with a kidney care team.
Winnipeg, ManitobaAges 18 years+ - NCT05738330Recruiting
Symptom reporting during hemodialysis care
This study looks at how well a new phone or computer system can help people on hemodialysis report their symptoms. It may improve symptom tracking so clinics can better understand and respond to what you feel during treatment.
Waltham, MassachusettsAges 18 years+ - NCT05878171Recruiting
Choices about life-saving treatment for kidney failure patients
This trial looks at what patients with kidney failure prefer for life-sustaining treatments (like whether they would want certain life-prolonging care). Your answers may help improve how future care plans are discussed and tailored to patients’ wishes.
TaipeiAges 20 years+ - NCT05917795Recruiting
Endoscopic stomach reduction for weight loss before kidney transplant
This trial tests an endoscopic procedure that helps reduce stomach size to support weight loss in people with severe kidney disease who may need a kidney transplant. It may help some patients meet transplant-center weight requirements and potentially improve readiness for transplant care.
RomeAges 18–70 - NCT05931276RecruitingPhase 3
Beta blocker choice may improve heart outcomes on dialysis
This phase 3 study tests whether a specific beta blocker selection on hemodialysis can improve cardiovascular outcomes. It focuses on certain beta blockers commonly used through the VA pharmacy and compares them in a randomized way.
Long Beach, CaliforniaAges 18 years+ - NCT06001827Recruiting
Study of a wrap to help new dialysis access points heal
This trial tests a special wrap placed around a new arm access point for dialysis (called an AV fistula) to see if it helps the access stay healthy and work better. It is for people who need a new AV fistula for kidney dialysis.
Bullhead City, ArizonaAges 18 years+ - NCT06056102RecruitingPhase 1
CAR-T cell therapy to help highly sensitized kidney transplant patients
This trial tests whether a special immune cell treatment (CAR-T cells) can lower the antibodies that make it very hard for you to receive a kidney transplant. If it works, you might become eligible for a transplant sooner.
Boston, MassachusettsAges 18–65 - NCT06065982Recruiting
Study of a method for placing a dialysis catheter (PREDICT)
This study watches how well a certain method (percutaneous) works for placing a peritoneal dialysis (PD) catheter, which is a soft tube used for a type of kidney dialysis. By tracking patients’ experiences before and after the procedure, the study aims to improve care for people with kidney failure.
BrusselsAges 18 years+ - NCT06089473Recruiting
Home Exercise Program for Frail Kidney Transplant Candidates
This study tests whether a 12-week home exercise program (supervised by video calls) can help people who are frail feel stronger and healthier before a kidney transplant. You'll do exercises at home and connect with a trainer online.
Montreal, QuebecAges 18 years+ - NCT06314503Recruiting
Safety study of a new peritoneal dialysis device for kidney patients
This trial tests a new device called WEAKID for people on peritoneal dialysis. It aims to see if the device is safe to use. Participants must have been on PD for at least 3 months and have no recent infections or catheter problems.
Modena, ModenaAges 18 years+ - NCT06356168Recruiting
Virtual reality for kidney disease patients on dialysis
This trial tests whether using virtual reality (a special headset that shows you a different world) can help people with end-stage kidney disease feel better during their dialysis sessions. It may help reduce stress or discomfort.
Philadelphia, PennsylvaniaAges Any age - NCT06367205Recruiting
Fluid and blood pressure management in kidney transplant
This trial tests a way to manage fluids and blood pressure during kidney transplant surgery to see if it improves recovery. It may be an option for people getting a kidney from a deceased donor.
Zhengzhou, HenanAges 18 years+ - NCT06383208Recruiting
Heart and kidney risk study for people with both diseases
This study looks at how well we can predict heart and kidney problems in people who have both coronary heart disease and chronic kidney disease. By analyzing certain markers, researchers hope to create a better risk assessment tool.
Beijing, Beijing MunicipalityAges 18–80 - NCT06402851RecruitingPhase 4
Blood thinner or none for atrial fibrillation with dialysis
This trial compares two types of blood thinners (vitamin K antagonists and factor Xa inhibitors) versus no blood thinner in people with atrial fibrillation who are on dialysis or have very advanced kidney disease. It aims to see which option is safest and most effective for preventing strokes and bleeds.
Salvador, Estado de BahiaAges 18 years+ - NCT07678073Recruiting
Comparing Anesthesia Types for Kidney Transplants
This study compares two types of anesthesia (general gas anesthesia vs. a spinal-plus-epidural method) during living-donor kidney transplants to see how they affect certain body signals related to cell health and aging. If you are having a kidney transplant from a living donor and are in good overall health, this trial could help doctors learn which anesthesia may be better for you.
Gaziantep, State/ProvinceAges 18–70 - NCT06660277Recruiting
Dialysis with expanded solute removal study
This trial tests a special dialysis filter (Elisio HX) that removes more waste products from the blood. It aims to see if this approach improves health outcomes for people on regular in-center hemodialysis.
London, OntarioAges 45 years+ - NCT06700876Recruiting
TB test study for kidney disease or transplant patients
This study looks at better ways to find hidden (subclinical) tuberculosis (TB) in people with serious kidney disease or those who have had a kidney transplant. If you have kidney failure on dialysis or have a kidney transplant, you may qualify and help improve TB detection.
BangkokAges 18 years+ - NCT06613568Recruiting
Testing a new home hemodialysis machine
This study tests a new home hemodialysis machine called the Moda-flx System. If you are on stable dialysis and have a care partner, you and your partner will learn how to use the machine at home, and the trial will see if it can safely and effectively replace your regular dialysis.
San Dimas, CaliforniaAges 18–80
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Common questions
- Are there clinical trials for end stage kidney disease?
- Yes. Clin2 currently lists 148 recruiting end stage kidney disease studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a end stage kidney disease trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a end stage kidney disease trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.