Clinical trials
End Stage Kidney Disease clinical trials
Below are recruiting end stage kidney disease clinical trials, each written for real people, not researchers. We’re tracking 150 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT05149196Recruiting
Goal-directed fluid and blood pressure plan after kidney surgery
This trial tests a carefully tailored plan for managing blood pressure and fluid during and after kidney removal surgery, to help reduce kidney injury after surgery. It may be especially helpful if you’re having one kidney removed for cancer and your baseline heart/kidney risk is not too high.
Beijing, Beijing MunicipalityAges 18 years+ - NCT06920927Recruiting
Testing an online decision aid for heart and kidney disease
This study is testing an online tool called 'My Heart and CKD' that helps people with both chronic kidney disease and heart disease make decisions about their care. The goal is to see if it is easy to use and helpful for patients and their doctors.
Calgary, AlbertaAges 18 years+ - NCT06997042Recruiting
Comparing Two Fistula Creation Techniques for Dialysis
This study compares two surgical techniques for creating an arteriovenous fistula (AV fistula), a special connection between an artery and a vein in the arm that makes dialysis easier. If you need dialysis for advanced kidney disease, this trial aims to see which method works better and lasts longer.
Barcelona, BarcelonaAges 18 years+ - NCT03374215Recruiting
Study hormone causes of high blood pressure in Black adults
This study looks at the body’s hormone signals to understand what causes primary aldosteronism (a condition that can lead to high blood pressure). By comparing clinical results and lab data, researchers hope to improve how the condition is diagnosed and managed, especially in Black participants.
Bethesda, MarylandAges 7–70 - NCT00977977RecruitingPhase 2
Rituximab plus cyclosporine for membranous kidney disease
This trial tests whether rituximab (an immune-targeting medicine) plus cyclosporine (another immune medicine) can better control protein leakage in the urine for people with idiopathic membranous nephropathy. It may help reduce long-lasting kidney damage risk when standard treatments like ACE inhibitor or ARB don’t control the protein level.
Bethesda, MarylandAges 18–90 - NCT04626167RecruitingEarly Phase 1
Testing a bladder transplant done with a kidney transplant
This early-phase study is testing a combined bladder and kidney transplant approach for people whose bladder problems damage the kidneys. The goal is to see if this treatment can improve bladder and kidney outcomes and be done safely.
Rochester, MinnesotaAges 1–60 - NCT07745920Recruiting
An online program for depression in people with adpkd
This study tests an internet-based program to help manage depression symptoms in people with ADPKD. The program may be a convenient way to get support for your mood without traveling to a clinic.
Rochester, MinnesotaAges 18–70 - NCT07203287RecruitingPhase 4
Comparing muscle relaxants in kidney disease patients during surgery
This trial compares two muscle relaxants, rocuronium and cisatracurium, to see which causes fewer complications in people with chronic kidney disease (not on dialysis) who need general anesthesia. If you have kidney disease and are having surgery that requires a breathing tube, this study may help determine the safer drug for you.
Galveston, TexasAges 18–80 - NCT03524222Recruiting
Home hospital care for adults after sudden illness
This trial tests whether certain adults can safely receive hospital-level care at home instead of staying in the hospital, using a home care team. It may help you recover in your own home if your condition fits their plan and you have support at home.
Boston, MassachusettsAges 18 years+ - NCT04984226RecruitingPhase 2
Sodium bicarbonate for kidney disease energy and acidity
This trial studies whether taking sodium bicarbonate changes “energy” in cells and improves metabolic acidosis (an acid build-up) in people with moderate-to-severe chronic kidney disease. You may be able to join if your kidney function and blood bicarbonate levels fit their targets and you meet safety rules.
Sacramento, CaliforniaAges 21–85 - NCT05321368Recruiting
Program to help control blood pressure and support health equity
This study tests a program that combines clinic care, community support, and phone-based monitoring to help people better manage blood pressure and related health problems. It aims to reduce health differences between groups that have been affected more by preventable disease.
Washington D.C., District of ColumbiaAges 18 years+ - NCT05832229RecruitingPhase 2
Studying rosuvastatin to slow liver scarring in cirrhosis
This Phase 2 trial tests whether rosuvastatin (a cholesterol-lowering medicine) can improve how well the liver functions and slow worsening scarring in people with cirrhosis. It also checks for side effects and safety.
La Jolla, CaliforniaAges 18–75 - NCT05880914Recruiting
Personalized treatment study for bone disease in kidney failure
This trial looks at a personalized approach to diagnosing and treating bone problems caused by long-term kidney disease. It may help by matching treatment plans to the type of bone turnover found in your tests or biopsy.
St Louis, MissouriAges 18 years+ - NCT06272578Recruiting
Heart and kidney health study for chronic disease patients
This study checks how heart and kidney health are related in people with kidney disease, diabetes, high blood pressure, or high cholesterol. It is a single visit with tests to see if certain heart problems are common in these conditions.
Wedding, State of BerlinAges 18 years+ - NCT06306963Recruiting
Stomach blood vessel condition and digestion symptoms study
This study looks at people with a stomach condition called gastric antral vascular ectasia (GAVE) to understand how it affects digestion and causes symptoms. Researchers want to learn if stomach muscle function problems are common in this condition.
Rochester, MinnesotaAges 19 years+ - NCT06310967RecruitingPhase 1/Phase 2
Study of IG3018 for high uric acid with or without kidney disease
This trial tests a new medicine, IG3018, to lower high uric acid levels in people with or without chronic kidney disease. It aims to find the right dose and see if it's safe.
Botany, New South WalesAges 18–75 - NCT06311240Recruiting
Chronic pain therapy in hemodialysis patients
This study looks at whether a certain kind of therapy can help people on dialysis who have chronic pain. If you have kidney failure and have been on hemodialysis for at least 3 months, you may be able to join.
Terrassa, BarcelonaAges 18 years+ - NCT07694544RecruitingPhase 1
Oral EC5026 study in people with kidney disease
This trial tests a medication called EC5026 in people with and without chronic kidney disease (CKD) to see how the body handles it. It helps understand if dose adjustments are needed for people with impaired kidney function.
Sacramento, CaliforniaAges 55 years+ - NCT06576479Recruiting
Supplement study for kidney disease and weight loss
This study tests if a special drink can improve nutrition and quality of life in people with chronic kidney disease (CKD) who are not on dialysis. It is for those who have lost weight or have poor appetite.
Guadalajara, JaliscoAges 18–90 - NCT06929169RecruitingPhase 2
SGLT2 inhibitor heart health study in dialysis patients
This study tests whether a medicine called an SGLT2 inhibitor (a type of diabetes drug also used for heart failure) affects the heart and blood vessels in people with kidney failure who are on dialysis. It will help doctors understand if this medicine is safe and helpful for dialysis patients.
Buenos Aires, Buenos AiresAges 18–70 - NCT07197645RecruitingPhase 1
Samarium for pain from bone cancer
This trial tests a new radioactive drug (samarium) given once to reduce severe bone pain from cancer that has spread to the bones. It is for people whose pain is not controlled by current treatments and who cannot have standard radiation.
Miami, FloridaAges 18 years+ - NCT01873235Recruiting
Study for adults with confirmed polycystic kidney disease
This study enrolls adults with autosomal dominant polycystic kidney disease (ADPKD) to better understand the disease and its related changes in the body. It may help researchers find improved ways to track the condition and support future treatments.
Baltimore, MarylandAges 18 years+ - NCT02497521Recruiting
Registry for adults with ADPKD starting tolvaptan
This registry study collects information about adults with autosomal dominant polycystic kidney disease (ADPKD) who are starting or already taking tolvaptan. It may help researchers understand how tolvaptan is used in real life and what outcomes look like over time.
Müllheim, Baden-WurttembergAges 18 years+ - NCT07522008Recruiting
Testing a blood-cleaning add-on for dialysis symptom relief
This trial tests whether adding a special blood-filtering device (hemoadsorption) to your regular dialysis treatment can reduce uncomfortable symptoms caused by kidney failure, like fatigue or itching. Researchers will track how you feel over time compared to standard dialysis alone.
Cagliari, ItalyAges 18 years+
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Common questions
- Are there clinical trials for end stage kidney disease?
- Yes. Clin2 currently lists 150 recruiting end stage kidney disease studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a end stage kidney disease trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a end stage kidney disease trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.