Clinical trials
Endometrial Cancer Stage I clinical trials
Below are recruiting endometrial cancer stage i clinical trials, each written for real people, not researchers. We’re tracking 134 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT04403867Recruiting
Study of tiny cancer spread found in sentinel lymph nodes
This trial studies whether very small deposits of cancer (called micrometastasis or isolated tumor cells) are found in sentinel lymph nodes in early endometrial or cervical cancer. The goal is to better understand what these findings may mean for cancer spread and treatment planning.
MilanAges 18 years+ - NCT06038032Recruiting
Healthy lifestyle after endometrial cancer
This trial tests a program to help endometrial cancer survivors improve their diet, physical activity, and weight. It aims to see if these changes can reduce the risk of the cancer coming back and improve overall health.
Edmonton, AlbertaAges 18 years+ - NCT05855941Recruiting
Imaging tests to better predict and diagnose gynecologic cancers
This trial studies how well medical imaging (especially MRI) can help predict outcomes and improve diagnosis in people newly diagnosed with certain gynecologic cancers. It may help doctors make more accurate treatment decisions by comparing imaging results to the final cancer type and stage.
UmeåAges 18 years+ - NCT06432478Recruiting
3D printed applicators for internal radiation in gynecologic cancer
This trial tests a custom 3D-printed applicator used during brachytherapy (internal radiation) for women with gynecologic cancers. It aims to deliver radiation more precisely to the tumor, possibly reducing side effects.
St Leonards, New South WalesAges 18 years+ - NCT07200466Recruiting
Personalized risk assessment for endometrial cancer
This trial uses a prediction model to better estimate the risk of endometrial cancer coming back. It aims to help doctors and patients make more personalized treatment decisions after surgery.
Arnhem, GelderlandAges 45 years+ - NCT07546825Recruiting
Minimally invasive versus open surgery for endometrial cancer staging
This trial compares two surgical approaches for treating endometrial cancer: traditional open surgery (laparotomy) versus minimally invasive keyhole surgery (laparoscopy). The goal is to determine which method is safer and more effective for removing the uterus, ovaries, and lymph nodes while staging the cancer.
AsyutAges Any age - NCT04774419RecruitingPhase 2
Radiation plus dostarlimab for post-surgery endometrial cancer
This Phase 2 study tests whether adding dostarlimab (an immunotherapy medicine) to radiation after surgery can lower cancer returning and improve outcomes. It’s for people with certain endometrial cancers found to have specific genetic/molecular changes and who have stage III/IVA disease after surgery.
Basking Ridge, New JerseyAges 18 years+ - NCT06952504RecruitingPhase 3
Comparing two drug combos for advanced endometrial cancer
This trial tests a new drug combination (sacituzumab tirumotecan plus pembrolizumab) against pembrolizumab alone for people with a specific type of advanced or recurrent endometrial cancer that has normal mismatch repair function. It aims to see which treatment works better.
Mobile, AlabamaAges 18 years+ - NCT05255653RecruitingPhase 2/Phase 3
Personalized after-surgery treatment for endometrial cancer by tumor type
This trial studies which after-surgery (adjuvant) treatment works best when endometrial cancer is classified by specific tumor DNA/molecular features. You may be offered treatment based on the tumor results, aiming to improve outcomes and lower the risk of the cancer coming back.
TorontoAges 18 years+ - NCT06680791Recruiting
Endometrial cancer study on recurrence prevention and lifestyle
This study looks at how your cancer type and daily habits might help prevent endometrial cancer from coming back. It only requires that you've had endometrial cancer and a hysterectomy.
PragueAges Any age - NCT07309952RecruitingPhase 2
Chemo, immunotherapy and targeted radiation before surgery for advanced lung cancer
This trial tests a new approach for people with certain advanced non-small cell lung cancer (NSCLC) that has spread to lymph nodes in the chest but might still be removed. It combines a short course of high-precision radiation, immunotherapy (sintilimab), and standard chemotherapy before surgery to see if it can improve outcomes.
Guangzhou, GuangdongAges 18–75 - NCT07109726RecruitingPhase 1/Phase 2
Testing TER-2013 for advanced tumors with AKT/PI3K/PTEN changes
This trial tests a new drug called TER-2013, alone or combined with another drug (fulvestrant), for people with advanced solid tumors that have specific genetic changes in the AKT/PI3K/PTEN pathway. It aims to see if the drug is safe and effective.
Orlando, FloridaAges 18 years+ - NCT07371663RecruitingPhase 1/Phase 2
TCC1727 combination therapy for advanced solid tumors
This trial tests a new drug, TCC1727, combined with other treatments for people with advanced solid tumors that have stopped responding to standard therapy. It aims to see if these combinations can help shrink or control the cancer.
Beijing, Beijing MunicipalityAges 18 years+ - NCT05123482RecruitingPhase 1/Phase 2
Early study of AZD8205 for advanced solid tumors
This Phase 1/2 study tests how safe and effective AZD8205 is for people with advanced or metastatic solid cancers that have come back or spread after standard treatments. It may help by finding the right dose and whether AZD8205 works alone or with another treatment in different cancer types.
Duarte, CaliforniaAges 18 years+ - NCT06432036RecruitingPhase 1/Phase 2
Y90 Radioembolization for Early Kidney Cancer
This trial tests a treatment called Y90 radioembolization for people with early-stage kidney cancer who cannot have surgery or ablation. Tiny radioactive beads are delivered through a catheter to the tumor's blood supply to destroy it from the inside.
Los Angeles, CaliforniaAges 18 years+ - NCT06354738Recruiting
Endometrial cancer study with genetic and surgical insights
This study looks at combining genetic testing with surgical exams to better understand endometrial cancer. It may help doctors see which treatments could work best for you.
LeuvenAges 18 years+ - NCT07198074RecruitingPhase 3
Testing Avastin added to chemo plus Keytruda for certain endometrial cancer
This study tests adding Avastin (bevacizumab) to the standard combination of chemotherapy (carboplatin and paclitaxel) plus immunotherapy (Keytruda) for advanced or recurrent endometrial cancer with a specific genetic makeup (pMMR and TP53 mutation). The goal is to see if adding Avastin helps shrink tumors or slow their growth.
Birmingham, AlabamaAges 18 years+ - NCT06906341RecruitingPhase 2
Relacorilant combo for gynecologic cancers
This trial tests a drug called relacorilant combined with different treatments for ovarian, fallopian tube, primary peritoneal, or endometrial cancers. It may help patients whose cancer has stopped responding to standard therapies.
Birmingham, AlabamaAges 18 years+ - NCT05564377RecruitingPhase 2
Find targeted cancer treatments using genetic testing
This study matches people with advanced solid tumors to targeted treatment plans based on genetic testing. It also requires tumor sample testing to help doctors choose the most promising therapy for your specific tumor changes.
Birmingham, AlabamaAges Any age - NCT07258186Recruiting
Endometrial cancer organoid study
This study creates miniature 3D versions of endometrial cancer tumors (organoids) from tissue samples taken during surgery. The goal is to better understand the disease and find personalized treatments.
Roma, RomaAges 18 years+ - NCT07041606Recruiting
A study on advanced endometrial cancer in Russia
This study looks at genetic profiles and first treatments for advanced or aggressive endometrial cancer in women in Russia. It aims to understand how genetic information might guide better treatment choices.
ArkhangelskAges 18 years+ - NCT06974110RecruitingPhase 1
Study of a new drug for advanced solid tumors with MSI-H or dMMR
This trial tests an oral medication called MOMA-341 in people with advanced solid tumors that have high microsatellite instability (MSI-H) or mismatch repair deficiency (dMMR). It aims to see if the drug can help when prior immunotherapy hasn't worked or isn't available.
Phoenix, ArizonaAges 18 years+ - NCT06340568RecruitingPhase 3
Study of an experimental drug vs. chemo for recurring uterine cancer
This trial is testing an experimental therapy against standard chemotherapy for people with endometrial cancer that has come back. The study looks for a certain protein (HER2) on cancer cells to decide which treatment group you may be in.
New Haven, ConnecticutAges 18 years+ - NCT06413992RecruitingPhase 2
Camrelizumab plus fluzoparib for TP53-mutated endometrial cancer
This trial tests a combination of two drugs, camrelizumab (an immunotherapy) and fluzoparib (a PARP inhibitor), for people with a specific type of endometrial cancer that has a TP53 gene mutation. It may offer a new option for advanced or recurrent disease after limited prior treatment.
Beijing, Beijing MunicipalityAges 18 years+
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Common questions
- Are there clinical trials for endometrial cancer stage i?
- Yes. Clin2 currently lists 134 recruiting endometrial cancer stage i studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a endometrial cancer stage i trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a endometrial cancer stage i trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.