Clinical trials
Stage III Endometrial Cancer clinical trials
Below are recruiting stage iii endometrial cancer clinical trials, each written for real people, not researchers. We’re tracking 61 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT04453904Recruiting
Testing best added chemo and radiation after stage III uterine cancer
This study compares different ways of giving radiation and chemotherapy after surgery for stage III endometrial (uterine) cancer. It aims to find which approach works best to reduce cancer risk and improve outcomes.
Beijing, Beijing MunicipalityAges Any age - NCT04504006Recruiting
Tracking surgery choices for lymph node spread in endometrial cancer
This is an observational study that follows people with endometrial cancer who have had surgery to check and remove pelvic (and sometimes paraaortic) lymph nodes. It looks at how different surgical approaches and any added treatment affect local control (keeping cancer from coming back in the pelvis/nearby areas).
Essen, North Rhine-WestphaliaAges 18 years+ - NCT04845828Recruiting
Sentinel node biopsy versus full node removal in early uterine cancer
This study compares two ways to check lymph nodes during surgery for early-stage endometrial (uterine) cancer: sentinel node biopsy versus removing more lymph nodes. It may help find whether the less extensive approach can stage the cancer accurately with fewer side effects.
SeoulAges 20–80 - NCT03621904Recruiting
Predicting response to hormone treatment in endometrial cancer
This study looks at whether biopsy test results can help predict how well hormone therapy will work for advanced or recurrent endometrial cancer. It may help doctors choose the most effective hormonal treatment sooner.
NijmegenAges 18–110 - NCT06028724Recruiting
Looking for cancer mutations using a blood test
This study uses a blood test (liquid biopsy) to find genetic changes in advanced solid tumors. It may help doctors choose the right treatment and monitor how well it works over time.
Aviano, PordononeAges 18 years+ - NCT05876130Recruiting
Radiation after surgery for stage III uterine cancer
This trial studies a specific type of radiation treatment given after surgery for people with stage III endometrial (uterine lining) cancer. It’s meant to see how well this “shorter/targeted” radiation approach works to help control the cancer after hysterectomy and staging.
SeoulAges 20–80 - NCT07831902RecruitingPhase 3
Hormone tablets plus radiotherapy for certain endometrial cancers
This trial compares two ways to treat endometrial cancer after surgery: a new option of just radiotherapy plus a daily hormone tablet (progestin) versus the current standard of radiotherapy plus chemotherapy. It aims to see if the new option works just as well with fewer side effects.
BathAges 18 years+ - NCT07779109Recruiting
Shorter radiation course for endometrial cancer after surgery
This study tests a shorter, more intense course of radiation therapy after surgery for endometrial cancer. It aims to see if it is safe and works as well as standard radiation, while possibly reducing treatment time.
Zaragoza, ZaragozaAges 18–110 - NCT07741968Recruiting
Online program to ease fear of cancer returning
This study tests an online program designed to help women with advanced or certain types of breast or gynecologic cancer manage their fear of the disease progressing or returning. The program aims to reduce anxiety and improve quality of life.
Arcadia, CaliforniaAges 18 years+ - NCT03438474Recruiting
Lymph node surgery study for certain early endometrial cancers
This trial studies whether adding lymph node removal (lymphadenectomy) during surgery helps people with certain early-stage endometrial cancer. It focuses on patients who do not have visibly enlarged lymph nodes and who can safely have the operation.
AalenAges 18–75 - NCT06278857RecruitingPhase 2
Dostarlimab for early-stage MMR deficient endometrial cancer
This trial tests the drug dostarlimab for patients with early-stage endometrial cancer that is MMR deficient. It aims to see if the treatment is safe and effective for those who want to preserve their uterus or cannot have surgery.
Sydney, New South WalesAges 18 years+ - NCT07377734RecruitingPhase 2
Collagen injection before fertility-sparing therapy for early endometrial cancer
This trial tests whether an injection of type III collagen into the uterus before standard progestin therapy can help preserve fertility in women with very early endometrial cancer or atypical hyperplasia. It is designed for women who want to keep the option of having children.
BeijingAges 18–45 - NCT07316361Enrolling by invitationEarly Phase 1
Personalized vaccine for high-risk endometrial cancer
This trial tests a personalized vaccine made from your tumor's unique proteins to help your immune system fight high-risk or advanced endometrial cancer. It is given along with your regular cancer treatments.
Thessaloniki, ThessalonikiAges Any age - NCT07270666Recruiting
ctDNA test for guiding endometrial cancer treatment decisions
This trial tests whether a blood test for ctDNA (cancer DNA fragments) can help doctors decide if standard chemotherapy plus an immunotherapy drug is working for people with advanced or recurrent endometrial cancer. It may help tailor your treatment based on how the cancer responds.
Basking Ridge, New JerseyAges 18 years+ - NCT06502743RecruitingPhase 2
Study of chemotherapy and pembrolizumab with or without nesuparib for endometrial cancer
This trial tests a chemotherapy combination (carboplatin and paclitaxel) plus the immunotherapy drug pembrolizumab, followed by maintenance pembrolizumab either alone or with a PARP inhibitor called nesuparib. It is for women with advanced or recurrent endometrial cancer that is MMR-proficient (a type where the cells have a normal ability to fix DNA).
Kyeonggi-doAges 19 years+ - NCT05795244RecruitingPhase 2
Nivolumab for resected mismatch-repair deficient endometrial cancer
This trial studies nivolumab (an immune therapy that helps your body recognize cancer) after surgery for endometrial cancer that has mismatch-repair deficiency (MMR-d) or high microsatellite instability (MSI-H). It aims to lower the chance the cancer comes back by treating “leftover risk” after the tumor is removed.
SeoulAges 20 years+ - NCT07062016Recruiting
Studying high-risk endometrial cancer with blood and tissue tests
This trial studies tumor DNA in blood and tissue from people with aggressive endometrial cancer to better understand the disease. You donate samples during surgery and follow-up visits.
Rochester, MinnesotaAges 18 years+ - NCT07022483RecruitingPhase 3
New drug vs standard chemo for HER2-positive endometrial cancer
This trial compares a new targeted medicine (trastuzumab deruxtecan) against standard chemotherapy for women with a certain type of advanced endometrial cancer that has high levels of HER2 protein. It's for people whose cancer is newly diagnosed and has spread to nearby tissues but not to distant organs.
Fort Lauderdale, FloridaAges 18 years+ - NCT06989112RecruitingPhase 3
First-line treatment for advanced or recurrent endometrial cancer
This trial tests a new combination of drugs for endometrial cancer that has spread or come back. It aims to see if these drugs can shrink tumors and help people live longer. It is for tumors that have a certain protein (HER2) and are mismatch repair proficient (meaning they have a normal DNA repair system).
Tucson, ArizonaAges 18 years+ - NCT06855706Recruiting
Personalized physical activity program for ovarian and endometrial cancers
This study tests whether a personalized, automated physical activity program (using a Fitbit and continuous glucose monitor) can improve immune function and health outcomes in people with advanced ovarian, primary peritoneal, fallopian tube, or newly diagnosed endometrial cancer. You'll wear an activity tracker, answer questionnaires, and provide blood and stool samples at Roswell Park.
Buffalo, New YorkAges 18 years+ - NCT06834204Enrolling by invitation
Better care coordination for cancer survivors
This study tests a program to improve communication between your cancer team and your regular doctor. If you have heart or diabetes risks and you're being treated for breast, prostate, bladder, or endometrial cancer, this trial may help coordinate your care.
New Brunswick, New JerseyAges 18 years+ - NCT06751589RecruitingEarly Phase 1
Weight loss drug study for people with endometrial cancer
This study tests if adding a weight loss medication (tirzepatide or semaglutide) during chemotherapy helps people with early-stage endometrial cancer who are overweight or have diabetes. It aims to see if weight loss can improve treatment outcomes.
Basking Ridge, New JerseyAges 18 years+ - NCT06712472RecruitingPhase 3
Testing maintenance olaparib versus observation after chemoradiation for p53 abnormal endometrial cancer
This trial tests whether taking a daily pill called olaparib after standard chemoradiation can help prevent endometrial cancer with a p53 mutation from coming back. Half of participants will receive olaparib, and the other half will just be watched closely.
AlbiAges 18 years+ - NCT06586957RecruitingPhase 1
Study of NKT3964 for advanced solid tumors
This trial tests an experimental drug called NKT3964 for people with certain advanced cancers that have stopped responding to standard treatments. It aims to see if the drug can shrink tumors or slow their growth.
Little Rock, ArkansasAges 19 years+
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Common questions
- Are there clinical trials for stage iii endometrial cancer?
- Yes. Clin2 currently lists 61 recruiting stage iii endometrial cancer studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a stage iii endometrial cancer trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a stage iii endometrial cancer trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.