Clinical trials · Ohio
Epilepsy clinical trials in Ohio
We’re tracking 17 recruiting epilepsy studies with a site in Ohio — including Phase 1/Phase 2, Phase 2, Phase 2/Phase 3 and Phase 3 studies, each written for real people, not researchers.
Recruiting studies in Ohio
- NCT06608966Recruiting
Epilepsy Journey: Helping Teens Manage Daily Challenges
This study tests a program called Epilepsy Journey to help teenagers with epilepsy improve skills like planning, organizing, and staying on task. It is designed for teens who struggle with these thinking skills and live at home with a caregiver.
Cincinnati, OhioAges 13–17 - NCT07110454Recruiting
Long-term follow-up study for epilepsy monitoring implant
This study follows people who previously enrolled in the DETECT study and had a Minder device implanted to monitor brain activity. The goal is to see how the device performs over a longer period of time.
Cleveland, OhioAges 18–75 - NCT06052605Recruiting
Healthy aging study for older adults with epilepsy
This study looks at healthy aging in people with epilepsy. You will fill out a survey to help researchers understand your experiences and needs.
Cleveland, OhioAges 55–90 - NCT06265103Recruiting
Epilepsy learning healthcare system registry
This is a registry study that collects information from people being treated for epilepsy at participating healthcare centers. The goal is to improve care by learning from real-world patient data.
Cincinnati, OhioAges Any age - NCT07110337Recruiting
Diagnosing epilepsy to help guide treatment
This trial tests a new device to help diagnose epilepsy in people whose previous EEG brain monitoring did not give clear answers. If you have drug-resistant epilepsy with at least one seizure a month on average, this study may help find better treatment options.
Clevland, OhioAges 18–75 - NCT07219407RecruitingPhase 2
Long-term safety study of RAP-219 for focal seizures
This study tests the long-term safety and effectiveness of RAP-219, an investigative medication for focal epilepsy. It is for people who already completed an earlier study of RAP-219, have a type of epilepsy that doesn't respond to standard medicines, and use a surgically implanted brain device (RNS system) to help manage seizures.
Cleveland, OhioAges 18–70 - NCT07563881RecruitingPhase 3
Testing RAP-219 for Focal Seizure Control in Adults
This study tests whether a new medication called RAP-219 can help adults with focal seizures (seizures that start in one area of the brain) control their seizures better. You would take this medication alongside your current seizure drugs for about 12 weeks.
Cleveland, OhioAges 18–75 - NCT03400371Recruiting
Study of brain signals in juvenile myoclonic epilepsy
This study looks at EEG brain recordings in people with juvenile myoclonic epilepsy, especially those whose seizures started between ages 10 and 25. It may help researchers better understand how this epilepsy works and improve future care.
Columbus, OhioAges 10–40 - NCT05104983RecruitingPhase 2
Sirolimus to prevent first seizures in babies with TSC
This Phase 2 study tests whether sirolimus (a targeted medicine) can stop or slow the start of seizures in very young babies diagnosed with tuberous sclerosis complex (TSC). If seizures are prevented early, it may also help protect early brain development.
Cincinnati, OhioAges 1 day–6 months - NCT05992402Recruiting
Brain training program for epilepsy surgery readiness
This study tests a cognitive training program called ReBOOT for adults with epilepsy who are eligible for surgery. The program is done online and aims to improve brain function before surgery.
Cleveland, OhioAges 18–60 - NCT06063850RecruitingPhase 1/Phase 2
Gene therapy for adults with hard-to-control epilepsy
This trial tests a one-time gene therapy (AMT-260) for adults whose seizures start in one area of the brain (the temporal lobe) and aren't controlled by medication. The goal is to see if it's safe and reduces seizure frequency.
Cleveland, OhioAges 18–75 - NCT06132893RecruitingPhase 2/Phase 3
Testing BHV-7000 for hard-to-control focal seizures in adults
This study tests a new medicine called BHV-7000 for adults whose focal seizures (starting in one part of the brain) are not controlled by current treatments. The goal is to see if it can reduce seizures safely.
Canton, OhioAges 18–75 - NCT05718817Enrolling by invitationPhase 3
Long-term study of XEN1101 for people with epilepsy
This study gives XEN1101 in an open-label way (everyone knows they’re getting the drug) to people who finished earlier epilepsy studies. It aims to see how the treatment continues to work and whether it’s safe over the long term.
Akron, OhioAges 12 years+ - NCT07509190Recruiting
Helping patients learn about epilepsy surgery
This study aims to improve access to epilepsy surgery by educating patients about social factors that affect health. It includes surveys and focus groups for people with epilepsy who have undergone surgery evaluation at Cleveland Clinic.
Cleveland, OhioAges 18 years+ - NCT07509177Recruiting
Infrared light therapy for stress in epilepsy
This trial tests if infrared light therapy can help reduce stress in people with epilepsy. You would wear a ring to track your sleep and activity, and attend 45 light therapy sessions over several months.
Warren, OhioAges 18 years+ - NCT05469373Recruiting
Testing ESIS for children with hard-to-treat epilepsy
This trial studies ESIS in children and teens (ages 1 to 30) who have epilepsy that has not been controlled by medications. It may help by improving how doctors evaluate and treat seizures, especially when an additional brain-monitoring test is planned.
Cincinnati, OhioAges 1–30 - NCT06443463Enrolling by invitationPhase 2
Long-term safety of BHV-7000 in epilepsy
This study checks the long-term safety of BHV-7000 for people who already completed an earlier trial with this drug. You keep taking the same medicine while doctors watch for any side effects over time.
Canton, OhioAges 18–75
Epilepsy trials by city in Ohio
Where these studies are running in Ohio
Institutions with a site for the recruiting epilepsy studies listed above.
- Cleveland Clinic · 7 studies
- Cincinnati Children's Hospital Medical Center · 4 studies
- The Ohio State University Wexner Medical Center · 3 studies
- University of Cincinnati · 3 studies
- NeuroScience Research Center · 2 studies
- University Hospitals Cleveland Medical Center · 2 studies
- Akron Children's Hospital
- Holly Maggiano, MD
What taking part in a epilepsy study involves
A screening visit first
Before anything else, the study team checks whether you fit — usually a visit with some tests. You can stop at any point, and screening is typically free.
Care at a nearby site
Study visits happen at a clinic or hospital taking part. Many studies cover the cost of the study treatment and related visits, and some reimburse travel.
You stay in control
Taking part is voluntary and you can leave a study at any time, for any reason, without affecting your regular care.
The team decides eligibility
Our fit check is a helpful first read, not a decision. The study team makes the final call after reviewing your health history.
Epilepsy trials in other states
Common questions
- Are there epilepsy clinical trials in Ohio?
- Yes. We're currently tracking 17 recruiting epilepsy studies with a site in Ohio, each rewritten in plain language so you can see what it's testing and who it's for.
- How do I find out if I qualify for a epilepsy study in Ohio?
- Each study lists its eligibility rules — age, diagnosis, prior treatments. On every trial page we explain these in plain language and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Do I have to live in Ohio to take part?
- Not necessarily. These studies have a site in Ohio, but eligibility is about your health, not your address — some people travel to take part, and a few studies reimburse travel. The study team can tell you what's required.
- Does it cost anything to join a epilepsy trial?
- Using Clin2 is always free. Many trials cover the study treatment and related visits; some reimburse travel. The study team explains exactly what's covered before you decide.
Not the right time?
New epilepsy studies open in Ohio regularly. Set up a health profile and we’ll quietly watch for studies that fit you and email you when one opens.
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.