Clinical trials · Texas
Epilepsy clinical trials in Texas
We’re tracking 31 recruiting epilepsy studies with a site in Texas — including Early Phase 1, Phase 1, Phase 1/Phase 2, Phase 2, Phase 2/Phase 3 and Phase 3 studies, each written for real people, not researchers.
Recruiting studies in Texas
- NCT05135091RecruitingPhase 3
Cell therapy trial for hard-to-control one-sided temporal lobe epilepsy
This Phase 3 study tests a neural cell therapy (NRTX-1001) for adults whose seizures come from one side of the hippocampus and have not improved with standard seizure medicines. The goal is to reduce seizure frequency and improve seizure control where other treatments have not worked.
Houston, TexasAges 18–75 - NCT06265103Recruiting
Epilepsy learning healthcare system registry
This is a registry study that collects information from people being treated for epilepsy at participating healthcare centers. The goal is to improve care by learning from real-world patient data.
Dallas, TexasAges Any age - NCT07110337Recruiting
Diagnosing epilepsy to help guide treatment
This trial tests a new device to help diagnose epilepsy in people whose previous EEG brain monitoring did not give clear answers. If you have drug-resistant epilepsy with at least one seizure a month on average, this study may help find better treatment options.
Houston, TexasAges 18–75 - NCT07219407RecruitingPhase 2
Long-term safety study of RAP-219 for focal seizures
This study tests the long-term safety and effectiveness of RAP-219, an investigative medication for focal epilepsy. It is for people who already completed an earlier study of RAP-219, have a type of epilepsy that doesn't respond to standard medicines, and use a surgically implanted brain device (RNS system) to help manage seizures.
Houston, TexasAges 18–70 - NCT05608408Recruiting
Preserving Memory in People With Epilepsy Using Brain Stimulation
This study tests a type of brain stimulation in people with epilepsy to see if it can help preserve memory. Researchers will compare memory and brain effects over time to understand whether stimulation changes memory outcomes.
Houston, TexasAges 18–65 - NCT07594119RecruitingPhase 3
Testing RAP-219 to reduce seizures in focal epilepsy
This study tests a new medication called RAP-219 to see if it can reduce seizure frequency in adults with focal epilepsy (seizures starting in one area of the brain). You'll take the medication alongside your current seizure drugs and track your seizures daily using an app.
Houston, TexasAges 18–75 - NCT07287163Enrolling by invitationPhase 3
Long-term study of vormatrigine for epilepsy
This trial is for adults with epilepsy who have already taken vormatrigine in a previous study or through a special access program. It aims to collect ongoing safety and effectiveness information.
El Paso, TexasAges 18–85 - NCT05104983RecruitingPhase 2
Sirolimus to prevent first seizures in babies with TSC
This Phase 2 study tests whether sirolimus (a targeted medicine) can stop or slow the start of seizures in very young babies diagnosed with tuberous sclerosis complex (TSC). If seizures are prevented early, it may also help protect early brain development.
Houston, TexasAges 1 day–6 months - NCT06063850RecruitingPhase 1/Phase 2
Gene therapy for adults with hard-to-control epilepsy
This trial tests a one-time gene therapy (AMT-260) for adults whose seizures start in one area of the brain (the temporal lobe) and aren't controlled by medication. The goal is to see if it's safe and reduces seizure frequency.
Austin, TexasAges 18–75 - NCT06132893RecruitingPhase 2/Phase 3
Testing BHV-7000 for hard-to-control focal seizures in adults
This study tests a new medicine called BHV-7000 for adults whose focal seizures (starting in one part of the brain) are not controlled by current treatments. The goal is to see if it can reduce seizures safely.
San Antonio, TexasAges 18–75 - NCT06422923RecruitingPhase 1/Phase 2
Cell therapy for hard-to-treat epilepsy starting in both temporal lobes
This trial tests a new cell therapy (NRTX-1001) for people with epilepsy that starts in both sides of the brain's temporal lobes and doesn't get better with medication. It aims to reduce or stop seizures.
Houston, TexasAges 18–75 - NCT05718817Enrolling by invitationPhase 3
Long-term study of XEN1101 for people with epilepsy
This study gives XEN1101 in an open-label way (everyone knows they’re getting the drug) to people who finished earlier epilepsy studies. It aims to see how the treatment continues to work and whether it’s safe over the long term.
Austin, TexasAges 12 years+ - NCT06695767Recruiting
Behavioral therapy for epilepsy and depression in veterans
This trial tests a special therapy program for veterans who have both epilepsy and major depression. It uses talk therapy and text message support to help improve mood and seizure control.
Houston, TexasAges 18 years+ - NCT05283811Recruiting
Brain recording during epilepsy care, while doing a memory task
This study listens to brain activity in people with epilepsy who already need electrodes placed inside the brain. Researchers want to understand how different parts of the brain respond while you complete simple thinking and memory-related tasks, which may help improve future treatments.
Houston, TexasAges 10–64 - NCT07051629RecruitingPhase 1
Testing a new epilepsy medicine for safety in healthy people and patients
This study tests a new medicine called SIF001 for safety. It first gives the medicine to healthy volunteers, and then to people with epilepsy who have seizures even while on their current medicines. The goal is to find a safe dose.
Cypress, TexasAges 18–70 - NCT02846272Recruiting
Brain scans in children with hard-to-treat epilepsy
This study uses special brain imaging to look at how brain cells and networks work in children with intractable, or hard-to-treat, epilepsy. The goal is to connect the scan findings with what’s found in clinical evaluation to better understand the condition.
Houston, TexasAges birth–18 years - NCT07509177Recruiting
Infrared light therapy for stress in epilepsy
This trial tests if infrared light therapy can help reduce stress in people with epilepsy. You would wear a ring to track your sleep and activity, and attend 45 light therapy sessions over several months.
Houston, TexasAges 18 years+ - NCT03953768Recruiting
Testing a new vagus nerve stimulator for gut and immune health
This study looks at what happens to your immune system and stomach/gut function after getting a vagus nerve stimulator (VNS) for the first time for epilepsy. It may help doctors understand whether the device benefits more than seizures.
Houston, TexasAges birth–60 years - NCT05989893Recruiting
Mapping human thinking during brain surgery
This study maps how thinking works in people with epilepsy or brain lesions near important brain areas. It involves testing during brain surgery procedures to help researchers understand healthy brain function.
Houston, TexasAges 18–75 - NCT04677751Recruiting
Testing acupuncture effects in people with an implanted seizure device
This study looks at how adding acupuncture may change seizure activity in people who already have an implanted RNS seizure monitor and stimulator. You might benefit by learning whether acupuncture helps with seizure patterns without changing your usual treatments.
Houston, TexasAges 15–60 - NCT05085704Recruiting
Brain scans to study metabolism in healthy and diabetic people
This study uses MRI brain scans at different strengths to measure how the brain uses energy (metabolism) in health and in people with genetically confirmed G1D. It may help researchers understand brain energy changes related to metabolic disease and diabetes.
Dallas, TexasAges 16–80 - NCT05418894Recruiting
Study brain signals and improve treatment-resistant depression
This trial studies how brain activity relates to feelings and depression, using brain electrodes to measure signals. It’s meant for people with long-lasting, treatment-resistant major depression who may need stimulation while continuing psychiatric care.
Houston, TexasAges 22–70 - NCT05594017RecruitingEarly Phase 1
Test medicine to change brain rhythms and study memory
This early research study tests whether a medicine can change the brain’s electrical “rhythms” while people do memory-related tasks. It may help researchers understand how brain timing affects memory in people who are already being evaluated with specialized brain electrode monitoring.
Dallas, TexasAges 18–55 - NCT05600738Recruiting
Deep brain stimulation to treat epilepsy
This trial studies how adding or using deep brain stimulation devices affects people with epilepsy. It may help researchers understand which outcomes improve when these implanted devices are used.
Houston, TexasAges 18 years+
Epilepsy trials by city in Texas
Where these studies are running in Texas
Institutions with a site for the recruiting epilepsy studies listed above.
- The University of Texas Health Science Center at Houston · 10 studies
- Baylor College of Medicine · 3 studies
- University of Texas Southwestern Medical Center · 3 studies
- Michael E. DeBakey VA Medical Center · 2 studies
- University of Texas Health Science Center at San Antonio · 2 studies
- Advanced Neurology Epilepsy and Sleep Center ANESC Research
- Austin Epilepsy Care Center
- Baylor Scott & White Medical Center
What taking part in a epilepsy study involves
A screening visit first
Before anything else, the study team checks whether you fit — usually a visit with some tests. You can stop at any point, and screening is typically free.
Care at a nearby site
Study visits happen at a clinic or hospital taking part. Many studies cover the cost of the study treatment and related visits, and some reimburse travel.
You stay in control
Taking part is voluntary and you can leave a study at any time, for any reason, without affecting your regular care.
The team decides eligibility
Our fit check is a helpful first read, not a decision. The study team makes the final call after reviewing your health history.
Epilepsy trials in other states
Common questions
- Are there epilepsy clinical trials in Texas?
- Yes. We're currently tracking 31 recruiting epilepsy studies with a site in Texas, each rewritten in plain language so you can see what it's testing and who it's for.
- How do I find out if I qualify for a epilepsy study in Texas?
- Each study lists its eligibility rules — age, diagnosis, prior treatments. On every trial page we explain these in plain language and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Do I have to live in Texas to take part?
- Not necessarily. These studies have a site in Texas, but eligibility is about your health, not your address — some people travel to take part, and a few studies reimburse travel. The study team can tell you what's required.
- Does it cost anything to join a epilepsy trial?
- Using Clin2 is always free. Many trials cover the study treatment and related visits; some reimburse travel. The study team explains exactly what's covered before you decide.
Not the right time?
New epilepsy studies open in Texas regularly. Set up a health profile and we’ll quietly watch for studies that fit you and email you when one opens.
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.