Eye Disorders clinical trials

Autism brain study using MRI and social thinking tasks

This study uses MRI brain scans (already needed for medical reasons) to better understand how autism affects social thinking. It compares people with autism to healthy volunteers to see differences in brain activity.

Testing a new all-in-one eye measurement device

This study tests a new all-in-one device that measures several aspects of your eyes during a routine check-up. You just sit in front of it, no extra procedures. It's for both adults and children who already have an eye appointment.

Food supplement for dry eye caused by meibomian gland issues

This trial tests a food supplement designed to improve dry eye symptoms by targeting the microbiome. It may help if you have dry eye due to meibomian gland problems and are not using contact lenses or certain other eye treatments.

Pain and sleep behavior disorder study

This study looks at pain in people with a sleep condition called idiopathic REM sleep behavior disorder (iRBD), where people act out their dreams. It also includes a group of people with narcolepsy who have similar sleep issues. The goal is to understand how pain relates to these conditions.

Integrated trauma treatment for psychosis

This trial tests a new way to treat trauma in people who have psychosis (like schizophrenia). It combines therapy for trauma with your usual care, and aims to help you feel less distressed by past traumatic events.

Low-level light therapy for dry eye & skin pigmentation

This study tests whether low-level light therapy can improve dry eye symptoms caused by blocked oil glands (Meibomian Gland Dysfunction). It also looks at how the treatment affects skin pigmentation under the eyes.

Test using an app to map eye vision blind spots

This trial tests how well an EyeCTester smartphone app can measure vision blind spots and distorted vision compared with standard eye tests. If you qualify, you’ll do short near-vision and “Amsler grid” style tasks in the clinic to help confirm the app is accurate.

Comparing two therapies for trauma memories

This study compares two types of therapy—EMDR and imagery rescripting—to help people who have upsetting memories or nightmares from past events. It's for people with depression or PTSD, and you'll need to come to therapy twice a week.

The Effect of 5-hydroxytryptophan on ADHD Traits and Eye Movements

Hyaluronate eye drops for moderate to severe dry eye

This trial tests whether 0.28% sodium hyaluronate eye drops can help people with moderate to severe dry eye feel better. It's for patients who have significant dry eye symptoms and signs on an eye exam.

Can a memory task help reduce trauma symptoms before therapy?

This study tests whether a computer-based working memory task can help reduce symptoms of trauma and stress in people who are waiting to start therapy. If you have ongoing PTSD or severe stress and haven't yet started counseling, this could be a way to get early help from home.

Brain and eye tests of facial emotion recognition in autism

This study uses brain and eye measurements to understand how people recognize facial expressions, including in autism and related conditions. It may help researchers find markers that better explain autism-related symptoms and differences in processing emotions.

Predicting PTSD treatment success and handling non-response (PT-STRESS)

This study looks at how well PTSD treatments work and what happens when they don't. It tests ways to predict if a treatment will be successful for you.

Can a device that makes small noises improve balance and walking?

This study tests whether a device that plays small, random sounds (called stochastic noise) can help people feel steadier and walk better. It is for healthy adults of two age groups — those 60 and older, and those 21–59.

Rural autistic kids & language support study

This study is for autistic children or those with language delays, as well as their siblings or cousins, living in rural areas. It aims to help them express themselves better. Typically-developing children are also welcome as a comparison group.

Studying eye movements in long-term psychiatric medication use (Gaize device)

This trial uses a special device (Gaize) to track how your eyes move while you take psychiatric medication. It aims to see how long-term medication affects eye patterns, which could help doctors better understand treatment responses.

Eye contact therapy for adults with autism

This study tests a new program to help adults with autism feel more comfortable using eye contact. It is for people who are already getting treatment at a specialized autism center in the Netherlands.

Join a patient registry to support future research

This trial is a “patient registry,” which collects health information over time to help researchers plan and run future studies. It may help by contributing your experience so new treatments can be tested more effectively.

Early diagnosis of pregnancy and newborn health issues

This study looks at health data from pregnant women to find patterns that could help predict and catch health problems in mothers and babies early. It might offer better monitoring and care during and after pregnancy.

Kinetic Sand Therapy for Coordination in Autistic Children

This study tests whether playing with kinetic sand (a moldable sensory material) can help children with autism improve their reaching ability and hand-eye coordination. Researchers will measure changes in these skills over the course of the trial.

Tests an AI tool to diagnose isolated dystonia

This trial checks whether an AI (software) called DystoniaNet can accurately identify isolated dystonia using information from your evaluation, and compares its results to standard diagnosis. If you have focal, segmental, or generalized dystonia, this study may help improve faster and more accurate diagnosis in the future.

eyeGENE study: genetics of rare eye diseases

This study collects DNA samples and medical information from people with rare inherited eye diseases and their close relatives. The goal is to learn more about the genetic causes of these conditions and improve diagnosis and care.

Video games vs ball tossing for hand-eye coordination in older adults

This study tests whether playing video games or tossing balls can improve hand-eye coordination in older adults with mild memory problems. It is designed for people 60 and older who have mild cognitive impairment but are otherwise independent.

PTSD treatment research for adults in Ukraine

This study provides PTSD treatment for adults in Ukraine and measures whether symptoms improve. It aims to help people with distressing PTSD symptoms that affect their daily life.