Clinical trials
Fatigue clinical trials
Below are recruiting fatigue clinical trials, each written for real people, not researchers. We’re tracking 293 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07544303Recruiting
Fatigue and Mental Well-Being in MS Patients
This study explores how fatigue and mental health are connected in people with multiple sclerosis. Researchers will use audio sessions through headphones to understand your experiences and may help improve care for MS-related tiredness and mood.
VanAges 18–80 - NCT07543536RecruitingPhase 3
Megestrol Acetate for Fatigue in HER2+ Breast Cancer
This study tests whether a medication called megestrol acetate can help reduce severe tiredness and fatigue in people with advanced breast cancer who are receiving a targeted therapy called T-DXd (trastuzumab deruxtecan). Fatigue is a common side effect that can really impact quality of life.
Guangzhou, GuangdongAges 18–75 - NCT07525063Enrolling by invitation
Brain Stimulation for Fibromyalgia Pain Relief
This study tests whether a non-invasive brain stimulation technique (called TMS) can help reduce pain and improve mood in women with fibromyalgia. Researchers will use MRI scans and brain stimulation to understand how pain and reward circuits in the brain work.
Durham, North CarolinaAges 18 years+ - NCT07529197Recruiting
Study of Immunoadsorption Treatment for Post-Infectious ME/CFS
This study observes how a blood-cleaning treatment called immunoadsorption works in patients with ME/CFS (severe fatigue condition) who have specific immune markers. Researchers will track whether this treatment helps reduce symptoms and improve daily functioning.
Berlin, State of BerlinAges 18–65 - NCT07522398Recruiting
Power Training Study for Adults Over 65
This study tests whether short, intense strength exercises can help older adults build muscle and stay stronger. You'll do exercises designed to build power (the ability to move quickly and forcefully) over several weeks, and researchers will measure changes in your strength and daily function.
Diepenbeek, FlandersAges 65–85 - NCT07512895Recruiting
Muscle Relaxation Exercises for Depression and Fatigue in Dialysis Patients
This study tests whether guided muscle relaxation exercises can reduce depression and tiredness in people undergoing hemodialysis (a blood-filtering treatment). You would learn and practice simple exercises to relax your muscles, which may help improve your mood and energy.
Istanbul, IstanbulAges 18–75 - NCT07444333Recruiting
Heart function and fatigue in Friedreich's ataxia
This study looks at how the heart works during exercise and how that relates to fatigue in people with Friedreich's ataxia. You'll ride a stationary bike, and we'll measure your heart's output to understand fatigue better.
New York, New YorkAges Any age - NCT07434921Enrolling by invitation
Drowsy driving study for college students in Nevada
This study tests a program called 'Stay Awake, Stay Alive' to help college students reduce drowsy driving. If you're a student in Nevada who sometimes drives while sleepy, this may help you learn safer habits.
Las Vegas, NevadaAges 18 years+ - NCT07432074Enrolling by invitation
Acupressure and massage after cesarean section
This study tests whether acupressure (gentle pressure on specific points) or massage can help women recover after a planned cesarean. It aims to reduce pain and improve comfort without using extra medicine.
IstanbulAges 18–45 - NCT07429487Recruiting
Smartwatch activity tracking for fatigue after chemo
This study uses a smartwatch to track your physical activity and see if it helps reduce tiredness after finishing chemotherapy. It is for people who finished treatment for certain cancers less than 3 months ago.
NiceAges 18–75 - NCT07408765Recruiting
Physical activity and well-being in women with hypothyroidism
This study looks at how physical activity, social support, and fatigue affect psychological well-being in women with hypothyroidism. By joining, you may help researchers understand how lifestyle factors interact with your thyroid condition.
Oviedo, Principality of AsturiasAges 18 years+ - NCT07400848Recruiting
Symptoms and recovery after COVID-19 vaccine
This study looks at people who developed new, long-lasting symptoms after a COVID-19 vaccine. It aims to understand their symptoms, do lab tests, and see how they recover over time.
BernAges 18 years+ - NCT07404956Recruiting
Comparing surgical and N95 masks for operating room nurses
This study checks how wearing a surgical mask or an N95 mask affects the air quality during surgery (called surgical smoke). It is for operating room nurses who work with surgical smoke regularly.
Bartın, BartınAges 18 years+ - NCT06829940Recruiting
Baduanjin exercise for long COVID fatigue
This trial tests whether Baduanjin, a gentle mind-body exercise, can help people under 50 with long-standing chronic fatigue that's worse after COVID-19. It aims to see if this safe, low-impact practice improves energy and daily life without needing extra treatments.
CairoAges 18–50 - NCT07394361Enrolling by invitation
Clinical Pilates for women with lupus: fatigue and quality of life
This study tests whether clinical Pilates training can help reduce fatigue, improve mood, sleep, and overall quality of life in women with systemic lupus erythematosus. If you have low disease activity and are not already exercising regularly, you may be able to participate.
Adana, SaricamAges 18–55 - NCT05127980Recruiting
Study of immune antibodies after first-time EBV infection
This study looks at how the immune system’s antibodies behave after a first-time EBV infection, including whether they mistakenly react with the body’s own tissues. You might be offered a chance to help doctors understand why some people get longer or more intense symptoms from infectious mononucleosis.
BaselAges 18 years+ - NCT06211062RecruitingPhase 2
Probiotics for chronic fatigue syndrome with IBS
This study tests whether a specific mix of probiotics can help people with chronic fatigue syndrome (ME/CFS) who also have irritable bowel syndrome (IBS). It's a small trial to see if improving gut health can ease symptoms.
Fort Lauderdale, FloridaAges 45–70 - NCT07341789Enrolling by invitation
Vitamin B12 and orange extract for better performance
This study tests whether vitamin B12, natural orange extract, or both together can improve your physical and mental performance. It is for healthy men who exercise regularly and eat citrus fruits.
La Ñora, MurciaAges 18–45 - NCT06864156Recruiting
Molecules and vitamin levels in long COVID with brain fog
This study looks at certain molecules (called microRNAs) and vitamin B12 levels in people who have ongoing brain-related symptoms like depression, anxiety, or fatigue after a COVID-19 infection. It may help understand why some people have long-lasting symptoms and could lead to better treatments.
Mexico City, Mexico CityAges 18–65 - NCT07329842Recruiting
Bed height and CPR quality in pediatric simulation
This trial tests how the height of a hospital bed affects chest compression quality and the physical strain on doctors during CPR on a child-sized manikin. It may help find the optimal bed height to improve CPR effectiveness.
Antalya, AntalyaAges 18 years+ - NCT07316348Enrolling by invitation
Vocalization and natural pushing during labor
This study looks at whether making sounds (vocalizing) and pushing naturally during the pushing stage of labor—without medication—can help first-time mothers. You'll be asked to try either vocal pushing or silent pushing, and the researchers will see how it affects your labor.
Istanbul, AtaşehirAges 18 years+ - NCT07317271Recruiting
Virtual reality for burn symptoms
This trial tests a virtual reality program to help with symptoms like pain, trouble sleeping, and itching after a burn injury. You can join from home using your own device.
Baltimore, MarylandAges 18 years+ - NCT07320937Enrolling by invitation
Yiqi Fuyuan Paste formula for chronic fatigue syndrome
This trial tests whether a traditional Chinese medicine formula (Yiqi Fuyuan Paste) can help reduce fatigue in people with chronic fatigue syndrome. It is a double-blind, placebo-controlled study, meaning neither you nor the doctor will know which treatment you receive.
Shanghai, Pudong New AreaAges 18–65 - NCT06289114Recruiting
Can physical activity predict treatment success in rheumatoid arthritis?
This study tests if measuring your physical activity over a short time can help predict how well a new biologic medication will work for your rheumatoid arthritis. The goal is to find a simple way to see if the treatment is helping.
EsbjergAges 18 years+
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Common questions
- Are there clinical trials for fatigue?
- Yes. Clin2 currently lists 293 recruiting fatigue studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a fatigue trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a fatigue trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.