Clinical trials
Fatigue clinical trials
Below are recruiting fatigue clinical trials, each written for real people, not researchers. We’re tracking 288 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06292377Recruiting
Understanding Fatigue After First Stroke
This study looks at why people feel very tired after a first-time stroke. It involves questionnaires, thinking and memory tests, and a brain MRI to understand sleep, mood, and fatigue better.
BrusselsAges 18 years+ - NCT06308770Recruiting
Online group program for lupus fatigue
This trial tests a new online group program to help people with lupus manage chronic fatigue. Participants are randomly assigned to either the program or standard care, and all complete questionnaires online.
EdinburghAges 18–85 - NCT06321965Recruiting
Study of SMA in Children on SMN-Boosting Therapies
This study is looking for children and teens with spinal muscular atrophy (SMA) who are already on a treatment like Spinraza, Evrysdi, or Zolgensma. The goal is to understand different forms of SMA and how the treatment affects them over time.
Bron, RhoneAges birth–16 years - NCT06324422Recruiting
Exercise for Parkinson's fatigue
This trial tests if a structured exercise program can reduce fatigue in people with Parkinson's disease. It may help you feel less tired and improve daily function.
Aarhus, Central JutlandAges 40 years+ - NCT06371352Recruiting
Brain stimulation for sleep and fatigue in depression
This study tests a noninvasive brain stimulation treatment (theta burst stimulation) to see if it can improve sleep, reduce daytime sleepiness, and ease fatigue in people with depression.
WarsawAges 18–65 - NCT06434571RecruitingPhase 2
Comparing two sleep treatments for people with MS
This trial tests if talking with a sleep coach by video is better than a web-based program for improving sleep, reducing fatigue, and protecting the brain in people with multiple sclerosis (MS). Both treatments focus on changing thoughts and habits around sleep.
Kansas City, KansasAges 18–65 - NCT06472622RecruitingEarly Phase 1
Brain imaging study of pain and effort
This study uses brain scans to understand how people experience pain and effort. It compares healthy volunteers to people with ME/CFS to see if there are differences in brain activity.
Bethesda, MarylandAges 18–50 - NCT06474793Recruiting
Aromatherapy for fatigue and sleep in ICU nurses
This trial tests whether smelling lavender or chamomile essential oils can help intensive care nurses feel less tired and sleep better. If you work night shifts and have trouble sleeping or feel very fatigued, you might be able to join.
Kayseri, KocasinanAges 18 years+ - NCT06475339Recruiting
Heat and exercise study for healthy active adults
This study looks at how healthy, active people respond to repeated exercise in hot conditions. It will help researchers understand how your body handles heat and fatigue during demanding physical tasks.
Buffalo, New YorkAges 18–39 - NCT06485869Recruiting
Virtual reality for better quality of life during chemo
This trial tests if using virtual reality during chemotherapy sessions can improve your quality of life. It's for people who are about to start their first round of IV chemo and have sessions lasting more than 30 minutes.
ChaunyAges 18 years+ - NCT06989437RecruitingPhase 2/Phase 3
Study of Ponsegromab for Pancreatic Cancer with Weight Loss
This study tests an experimental drug called ponsegromab for people with advanced pancreatic cancer who experience severe weight loss and fatigue. It aims to see if the drug can help improve weight and energy levels while you continue standard chemotherapy.
Birmingham, AlabamaAges 18 years+ - NCT06511518Recruiting
Talking therapy for fatigue in advanced cancer
This study tests whether cognitive behavioral therapy, a type of talking therapy, can help reduce severe fatigue in people with advanced solid tumors or gliomas who are receiving or have completed palliative treatment. The goal is to see if this approach improves energy levels and quality of life.
Amsterdam, North HollandAges 18 years+ - NCT06562283Recruiting
Reproducibility of a fatigue test for spinal muscular atrophy
This study checks how consistent a fatigue test is for people with spinal muscular atrophy (SMA). It helps doctors better understand fatigue in SMA and may improve future care.
Saint-Etienne, FranceAges 6 years+ - NCT06565091Recruiting
Testing a new all-in-one eye measurement device
This study tests a new all-in-one device that measures several aspects of your eyes during a routine check-up. You just sit in front of it, no extra procedures. It's for both adults and children who already have an eye appointment.
RennesAges 4 years+ - NCT06567704Recruiting
Fatigue from immunotherapy in lung cancer: a patient interview study
This study aims to understand how maintenance immunotherapy affects fatigue in people with non-small cell lung cancer. Researchers will talk with patients to learn about their experiences.
Charlotte, North CarolinaAges 18 years+ - NCT06570226Recruiting
Tea and health in college students
This study looks at whether drinking tea can help college students with blood pressure, body shape, and vision. You may participate if you are a healthy college student without certain medical conditions or allergies.
TaipeiAges 15–22 - NCT06743490Recruiting
Tracking MG symptoms with smartphone recordings
This study uses your smartphone to record symptoms like slurred speech, hoarseness, arm fatigue, or droopy eyelids, making it easier for doctors to understand and monitor myasthenia gravis. Both people with MG and healthy volunteers can take part.
Leiden, South HollandAges 18 years+ - NCT07094269Recruiting
Fatigue management program for Parkinson's disease
This trial tests a structured fatigue management program compared to standard information to help people with Parkinson's disease better manage their energy. It aims to improve your confidence in using energy-saving strategies.
GenovaAges 18 years+ - NCT06628986Recruiting
Mindfulness and NLP for postpartum mood and breastfeeding
This study tests whether combining mindfulness (MBSR) and a gentle brain-training method (NLP) can help new mothers feel better after childbirth and improve their breastfeeding experience. It may be a good fit if you are a first-time mom who had a C-section and is breastfeeding.
Sanliurfa, Eyalet/YerleşkeAges 19–35 - NCT06633224Recruiting
Fatigue and biology in cancer patients getting chemoradiation
This study looks at why some people feel very tired during cancer treatment. Researchers will collect blood and stool samples to study how the body responds to chemotherapy and radiation.
San Francisco, CaliforniaAges 18 years+ - NCT06650813Recruiting
Adapting a fatigue program for sickle cell disease
This trial adapts the FACETS program, a fatigue-management course, for people with sickle cell disease. It aims to help participants better cope with fatigue and improve daily life.
GrenobleAges 18 years+ - NCT06668649Recruiting
Polish fatigue scale study for MS, ALS, or stroke
This study tests a Polish version of a scale that measures how tired people feel. It's for people with MS, ALS, or stroke, or healthy volunteers.
Krakow, Lesser Poland VoivodeshipAges 18 years+ - NCT06675344Recruiting
A device for fatigue, Raynaud's, and quality of life in scleroderma
This trial tests if a device called Apollo can help reduce fatigue and Raynaud's symptoms and improve quality of life in people with scleroderma (systemic sclerosis). You would use the device at home and track your symptoms using a smartphone app.
New Orleans, LouisianaAges 18 years+ - NCT06678347Recruiting
Leadership program for healthcare managers
This trial tests a program to help first-line managers in hospitals lead better and support their teams. It may benefit managers and their employees by improving work recovery and well-being.
GothenburgAges 18 years+
Hear when a new Fatigue trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.
Common questions
- Are there clinical trials for fatigue?
- Yes. Clin2 currently lists 288 recruiting fatigue studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a fatigue trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a fatigue trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.