Clinical trials
Fatigue clinical trials
Below are recruiting fatigue clinical trials, each written for real people, not researchers. We’re tracking 293 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT05984069Recruiting
Fatigue and frailty after ICU stay
This study looks at how feeling weak or frail after an ICU stay affects tiredness. It aims to find better ways to help people recover from serious illness.
Saint-EtienneAges 18 years+ - NCT07278973Recruiting
Dialysis study for people over 84 with kidney failure
This trial compares two types of dialysis (hemodiafiltration and standard hemodialysis) to see which works better for older adults with kidney failure. You may be eligible if you are over 84, have been on dialysis for at least 3 months, and are generally healthy enough to participate.
BretagneAges 85 years+ - NCT06884644Recruiting
Oxygen levels during death by squats
This study looks at how the oxygen levels in your blood and muscles change during a tough squat exercise called 'death by squats.' It may help us understand how the body handles intense exercise.
Munich, BavariaAges 18 years+ - NCT07273058Recruiting
High-intensity exercise for post-stroke fatigue
This study tests high-intensity interval training (HIIT) to reduce fatigue after a stroke. If you often feel tired and have had a stroke in the past 6 months to 5 years, this program may help you regain energy.
KowloonAges 40–80 - NCT07273123Recruiting
Chewing gum and fatigue in jaw joint health
This study tests if chewing sugar-free gum for a while can affect how tired you feel and how your jaw muscles work. It compares people with and without jaw joint problems (TMJ disorders).
Milan, MilanAges 19–35 - NCT07251608RecruitingPhase 1
Safety study of Niagen injections for fatigue
This trial tests whether Niagen injections are safe for people who feel tired. You would inject the study drug yourself at home for about three months.
Miami, FloridaAges 18 years+ - NCT07250555Recruiting
Basketball fatigue and energy study
This study looks at how basketball players' bodies produce energy and how tired they get during a game. It may help find ways to improve performance and recovery.
Trikala, ThessalyAges 18–30 - NCT07256795Enrolling by invitation
ME/CFS after COVID-19 vs. before the pandemic
This study looks at how the brain's protective barrier and immune system work in people with ME/CFS, comparing those who got sick before the COVID-19 pandemic to those who developed ME/CFS after a COVID-19 infection. It aims to understand why some people have lasting brain fog, fatigue, and other neuropsychiatric symptoms.
Baltimore, MarylandAges 18–70 - NCT07252219Recruiting
How ankle muscle fatigue affects balance in unstable ankles
This study looks at how getting your ankle muscles tired changes your ability to sense force and control movement. It compares people with chronic ankle instability to healthy volunteers to find better ways to prevent re-injury.
LjubljanaAges 18–45 - NCT07227441Recruiting
Chronic Infections and Inflammation in ME/CFS
This study looks at how chronic infections and inflammation affect people with ME/CFS (myalgic encephalomyelitis/chronic fatigue syndrome) compared to healthy people. Researchers want to understand what causes symptoms and find better ways to help.
San Francisco, CaliforniaAges 18 years+ - NCT07224646Recruiting
Light therapy for professional soccer players during a championship
This trial tests if a type of light therapy (called photobiomodulation) on the whole body can help professional soccer players recover faster and perform better during a championship. It involves 8 weeks of sessions alongside your regular training.
Porto Feliz, São PauloAges 18–35 - NCT07224009RecruitingPhase 2
Low dose naltrexone for fatigue in prostate cancer on hormone therapy
This trial tests if a low dose of the drug naltrexone can help reduce fatigue in men with prostate cancer who are currently receiving hormone therapy (ADT). It may offer a new way to manage tiredness during treatment.
Little Rock, ArkansasAges 18 years+ - NCT07225088Recruiting
Mental health support for Latino cancer patients
This study tests a mental health intervention called DESCANSO to help Latino people with cancer who feel depressed, have trouble sleeping, or are very tired. You may join if you are a Latino adult with stage I-III solid tumor cancer, speak Spanish, and are currently or recently finished treatment.
Basking Ridge, New JerseyAges 21–100 - NCT07228767Recruiting
Study on surgeons' mental tiredness based on surgery time
This study looks at how long surgeons operate and whether that affects their mental tiredness. It might help understand how to reduce fatigue in the operating room.
La Roche-sur-YonAges 18 years+ - NCT07209527Enrolling by invitationEarly Phase 1
Truway diagnostic tools in primary care
This trial tests new diagnostic tools that doctors can use in primary care. Researchers want to see if these tools help find the right diagnosis faster and more accurately.
New York, New YorkAges Any age - NCT06922409Recruiting
Light therapy for stroke recovery in rehabilitation
This trial tests whether exposure to naturalistic light can help reduce fatigue and depression after a stroke. It is designed for patients in a rehabilitation unit who are able to communicate and cooperate with simple physical exams.
Glostrup Municipality, Capital RegionAges 18 years+ - NCT06937190Recruiting
Does creatine before sleep improve power in active women?
This study tests if taking a small dose of creatine before bed helps women who exercise regularly perform better on power-based activities like jumping and sprinting. It's designed for healthy, young women who already do resistance training and want to see if a simple supplement can boost their nighttime recovery and next-day performance.
Shabestar, East Azerbaijan ProvinceAges 18–25 - NCT07200726Recruiting
Brain inflammation and thinking after heart surgery
This study looks at whether brain inflammation during heart surgery may affect memory and thinking. It includes people aged 60 and older who are having planned heart surgery.
Genk, LimburgAges 60 years+ - NCT07161245Recruiting
Fatigue relief study for primary biliary cholangitis
This trial tests a program of exercise, nutrition, and education to help reduce fatigue in people with primary biliary cholangitis. It aims to see if this program can improve energy and quality of life.
Barcelona, BarcelonaAges 18–80 - NCT07161531Recruiting
Testing muscle fatigue sensors in active teens
This trial checks if a sensor that measures muscle tiredness works reliably in teenagers who are physically active. If you play sports or dance regularly, your participation could help improve how we understand muscle fatigue.
WilrijkAges 13–19 - NCT06959069Recruiting
Intermittent Fasting, Sleep, and Quality of Life Study
This study tests whether intermittent fasting can improve sleep and quality of life in healthy adults. If you are generally healthy and not on specific medications or diets, you may be able to join.
BrusselsAges 18–65 - NCT07130825Recruiting
Physical activity, brain power, and mental fatigue
This study tests whether different types of physical activity can help you think more clearly and resist mental tiredness. If you are a healthy adult without any long-term health issues, you may be able to join.
KaunasAges 18–65 - NCT05741112Recruiting
Long COVID wearable study to track symptoms and help daily management
This study uses a wearable device to track symptoms and patterns in people with Long COVID, ME/CFS, and/or POTS. The goal is to see how wearable feedback and tracking tools may help you manage your symptoms.
La Jolla, CaliforniaAges 18 years+ - NCT07106255Enrolling by invitation
Task training for multiple sclerosis patients
This trial tests a task-oriented training program to help improve hand and finger movement in people with multiple sclerosis.
Granada, GranadaAges 18 years+
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Common questions
- Are there clinical trials for fatigue?
- Yes. Clin2 currently lists 293 recruiting fatigue studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a fatigue trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a fatigue trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.