Clinical trials
Fibrosis clinical trials
Below are recruiting fibrosis clinical trials, each written for real people, not researchers. We’re tracking 440 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06045702Recruiting
Study of CFTR gene in epididymal cells from surgery
This study collects a small tissue sample from the epididymis during planned surgery. The sample is used to study how the CFTR gene works, which may help understand fertility problems in men with cystic fibrosis.
BrestAges 18 years+ - NCT06047782Recruiting
MRI study of atrial scarring and stroke risk
This study uses a special heart MRI to look for scarring in the upper chambers of the heart (atria) that might cause hidden atrial fibrillation after a stroke with no known cause. It may help explain why the stroke happened and guide future treatment.
DijonAges 18 years+ - NCT06065852Recruiting
National registry for rare kidney diseases
This study creates a registry to collect health information from people with rare kidney diseases. It aims to improve understanding and future treatments by tracking patient experiences.
Bristol, South WestAges Any age - NCT06069115Recruiting
How radiation affects lung function in breast cancer patients
This study looks at how radiation therapy for breast cancer may affect your lungs over time. Researchers will measure lung function and see if problems develop, so they can better understand and protect patients.
Novosibirsk, Novosibirsk OblastAges 18 years+ - NCT06098417Recruiting
Fatty liver markers before weight-loss surgery
This study looks at special markers in the blood to better understand and predict a fatty liver condition called NAFLD. It focuses on people who are very overweight and are already planning to have weight-loss surgery.
TriesteAges 18–65 - NCT06125743Recruiting
Self-management program for head and neck swelling
This study tests a self-management program to help people with head and neck cancer manage swelling (lymphedema) and tightness (fibrosis) after treatment. It may be a good fit if you have finished cancer therapy, are cancer-free, and have access to internet at home.
Philadelphia, PennsylvaniaAges 18 years+ - NCT06147414Recruiting
Blood test for genetic disorders in pregnancy
This study tests a safer blood test to check for certain genetic disorders during pregnancy, instead of an invasive procedure like amniocentesis. It's for pregnant women who are at risk of passing on a known genetic condition.
ParisAges 18 years+ - NCT06165341RecruitingPhase 3
Fazirsiran for mild liver scarring in alpha-1 antitrypsin deficiency
This study tests an investigational drug called fazirsiran, which is designed to treat alpha-1 antitrypsin deficiency-related liver disease with mild scarring. The goal is to see if fazirsiran is safe and can improve or slow liver damage in people with the PiZZ genetic type.
Phoenix, ArizonaAges 18–75 - NCT06237335RecruitingPhase 2
Safety Study of RCT2100 for People with Cystic Fibrosis
This trial tests a new type of medicine called RCT2100 (CFTR mRNA) for people with cystic fibrosis who cannot take currently available CFTR modulators. It aims to see if the treatment is safe and tolerable, and may help improve lung function.
Birmingham, AlabamaAges 18–60 - NCT06242795RecruitingPhase 4
Hypertonic saline for non-cystic fibrosis bronchiectasis
This trial tests whether inhaling a saltwater solution (hypertonic saline) twice a day for 12 weeks can help people with bronchiectasis who have a chronic cough and have had flare-ups in the past. It aims to see if this treatment reduces mucus and improves quality of life.
Chapel Hill, North CarolinaAges 18 years+ - NCT06248580Recruiting
Finding HDV in Turkey Study
This trial is looking for adults in Turkey who have had a hepatitis B infection (HBsAg positive) for at least 6 months. The goal is to see if they also have a hepatitis D virus (HDV) infection. This may help doctors better understand and treat these infections.
AnkaraAges 18 years+ - NCT06267183RecruitingEarly Phase 1
Safety study of a new drug in healthy volunteers
This study tests a new investigational drug called SV001 in healthy volunteers to see if it is safe and how the body handles it. It is a first-in-human trial, meaning this drug has not been tested in people before.
ShanghaiAges 18–45 - NCT06293378Recruiting
Sulfasalazine for liver fibrosis and cirrhosis
This study tests if sulfasalazine, a medicine already used for other conditions, is safe and helpful for people with liver scarring (fibrosis or cirrhosis). It is for patients with cirrhosis caused by certain liver diseases, like PBC, hepatitis B, hepatitis C, or alcohol use.
Chongqing, Chongqing MunicipalityAges 18–70 - NCT06302270Recruiting
Kaftrio during pregnancy and after birth
This study looks at how the cystic fibrosis medication Kaftrio works during pregnancy and after childbirth. It follows women with cystic fibrosis who are already taking Kaftrio and their newborn babies.
StockholmAges Up to 50 years - NCT06304207Recruiting
Study comparing remote vs in-person exercise for lung disease
This study tests whether a telehealth exercise program works as well as in-person sessions for people with chronic lung disease. You may join if you recently finished rehab for your lung condition and can walk with or without help.
Charlestown, MassachusettsAges 40 years+ - NCT06325488Recruiting
Kidney Health Study in Fabry Disease
This study uses MRI scans to look at how Fabry disease affects the kidneys, including scarring, swelling, and oxygen levels. It may help researchers understand kidney problems better and find new ways to monitor the disease.
CopenhagenAges 18 years+ - NCT06339593RecruitingEarly Phase 1
Using MRI to Monitor CF Lung Health
This study uses MRI scans to monitor lung health in teens and young adults with cystic fibrosis who are taking Trikafta. It aims to find better ways to track how the disease affects the lungs over time.
Cincinnati, OhioAges 12–21 - NCT06341166Recruiting
Predicting heart scarring in mitral valve prolapse
This study looks at people with mitral valve prolapse (a common heart valve condition) to see if doctors can predict who might have scar tissue in their heart muscle. If you have this condition, joining could help improve understanding of your heart health.
Milan, MilanAges 18 years+ - NCT06409585Recruiting
Heart muscle disease imaging study for scarring
This study uses advanced imaging (PET/MR or PET/CT) to look at scarring (fibrosis) in the heart muscle. It is for people with various heart muscle diseases, including heart failure with preserved pumping, thickened heart muscle, high blood pressure-related heart damage, heart inflammation, and others.
Edinburgh, ScotlandAges 30–90 - NCT06477185RecruitingPhase 2
Preventing lung scarring after TB with doxycycline
This trial tests whether the antibiotic doxycycline can prevent lung scarring (fibrosis) after a serious TB infection. You may be eligible if you are currently being treated for active TB and have significant lung damage on your chest X-ray.
Kampala, KampalaAges 18–65 - NCT06504589Recruiting
Study for CF treatments for people without modulators
This study tests new treatments for cystic fibrosis in people who cannot take or choose not to take current CFTR modulators. It aims to find better options for managing CF.
Birmingham, AlabamaAges 12 years+ - NCT06512064Recruiting
Breath sound test for lung health
This study tests a new device that listens to your breathing to check lung health. It is for healthy people and those with asthma, COPD, CF, or other airway diseases.
Indianapolis, IndianaAges 8–70 - NCT06516237Recruiting
New imaging for fibrosis in ulcerative colitis
This study looks at new ways to detect scarring (fibrosis) in the bowel using advanced imaging and tests. It may help doctors better understand and monitor ulcerative colitis. If you are already having a colonoscopy, you may be able to join.
Milan, LombardyAges 18 years+ - NCT06527612Recruiting
Exercise's effect on lung disease and quality of life
This study looks at whether a personalized exercise program can improve quality of life and slow down lung disease in people with fibrosing interstitial lung disease. If you have trouble breathing when active and have been stable for the past month, you may be able to join.
Istanbul, ÜsküdarAges 18–75
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Common questions
- Are there clinical trials for fibrosis?
- Yes. Clin2 currently lists 440 recruiting fibrosis studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a fibrosis trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a fibrosis trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.