Clinical trials
Foot clinical trials
Below are recruiting foot clinical trials, each written for real people, not researchers. We’re tracking 292 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT05862246Recruiting
Kids with foot or leg pain and normal leg function
This trial looks at children who have tightness, foot pain, and/or leg pain, as seen in a pediatric orthopedic clinic. The goal is to study this problem in children who otherwise seem healthy and do not have signs of a different underlying foot or medical condition.
TrondheimAges 4–16 - NCT04575688Enrolling by invitationPhase 4
Nerve-block injection options for ankle or heel surgery
This trial compares two methods of numbing pain—an injection near the joint versus a nerve block—during ankle or hindfoot surgery. It aims to see which approach helps with comfort and recovery after surgery.
Germantown, TennesseeAges 18–80 - NCT04441983Recruiting
High-resolution foot MRI trial for patients and volunteers
This trial uses a powerful 7T MRI scanner to get detailed images of the foot and extremities. It includes patients with specific conditions (like Morton neuroma or tendon tears) and healthy volunteers, aiming to understand normal and diseased tissue better.
Zurich, Canton of ZurichAges 18 years+ - NCT07417436Recruiting
Graded motor imagery for foot or ankle osteoarthritis
This study tests a technique called graded motor imagery to see if it can reduce pain and improve movement in people with foot or ankle osteoarthritis. The treatment involves specific mental exercises, so it might help if you have chronic ankle pain.
Antalya, AntalyaAges 18 years+ - NCT05425979Enrolling by invitationPhase 4
Compare numbing medicines for ankle blocks in foot surgery
This study tests which numbing medicine works faster for an ultrasound-guided ankle nerve block during foot surgery: mepivacaine or bupivacaine. It may help improve comfort by reducing how long it takes for the numbness to start.
Rochester, MinnesotaAges 18 years+ - NCT06010433Recruiting
CERAMENT G treatment tracking study
This study tracks how well the CERAMENT G device works for people getting it as part of their treatment. It helps doctors gather real-world safety and effectiveness information.
San Diego, CaliforniaAges 18 years+ - NCT07008755Recruiting
Inhaled interferon for hand, foot, and mouth disease in children
This trial tests whether breathing in a medication called pegylated interferon helps children with mild hand, foot, and mouth disease recover faster. It is for children ages 1 to 6 who have had symptoms like fever or rash for 3 days or less.
ChengduAges 1–6 - NCT06532929Recruiting
Recovery after sports surgery with Teknimed products
This study is checking how well people recover after sports surgery using Teknimed products. It is for patients who had or will have a surgery with these products, and aims to see how the products perform in real life.
Aubenas, ArdècheAges 18 years+ - NCT07036120Recruiting
How Inserts and Exercises Affect Bunions and Your Legs
This study looks at how wearing special shoe inserts or doing specific exercises can correct bunions and affect your legs. It may help if you have bunions on both feet and are between 18 and 45 years old.
Guangzhou, GuangdongAges 18–45 - NCT06836934Enrolling by invitation
Knee brace vs. wedge for osteoarthritis
This study compares two non-surgical options—a soft knee brace vs. a lateral wedge shoe insert—to see which better relieves pain and improves function in people with knee osteoarthritis. If you're between 40 and 60 and have pain on one side of your knee, this study may help you find better relief.
Giza, Giza GovernorateAges 40–60 - NCT07298629Recruiting
Testing smart shoes for collapsed foot arches
This trial tests whether smart shoes or insoles can help people with flat feet. If you have a collapsed arch and a foot posture score of 6 or higher, you may be able to join.
TaipeiAges 20–65 - NCT07726459Recruiting
Balance and core stability in young football players
This study tests balance, core strength, and body awareness in amateur football players aged 13-19. It aims to see how these skills differ across age groups.
IstanbulAges 13–19 - NCT07735949Recruiting
Daily footwear and leg health in hemophilia knee replacement
This study looks at how the shoes you wear every day affect your leg health and movement. It involves adults with hemophilia who are about to have their first total knee replacement and are willing to participate in a pre-surgery exercise program.
Istanbul, IstanbulAges 18–35 - NCT06127316Recruiting
Heel lift height and foot pressure with custom braces
This study tests if changing the height of a heel lift in a custom foot brace can improve how weight is distributed on your foot after a serious ankle or hindfoot injury. If you have pain when walking, this could help find better ways to reduce that pain.
Iowa City, IowaAges 18–65 - NCT07193212Recruiting
Osteopathic treatment for low back pain and leg health
This study tests whether a hands-on osteopathic treatment can improve how your legs and feet work if you have chronic low back pain. It may help you understand if this type of manual therapy is a good option for your pain.
Auburn, AlabamaAges 18–65 - NCT07623408Recruiting
Foot Position During Achilles Tendon Pain Recovery
This study tests whether the position of your foot during exercises affects how well your Achilles tendon heals and how much pain you experience. Researchers will compare different foot positions during rehabilitation to see which works best for reducing Achilles tendon pain and improving tendon strength.
Leuven, Vlaams-BrabantAges 18–65 - NCT07720700Recruiting
Foot orthoses and walking in people with ataxia
This study tests if special shoe inserts (foot orthoses) can help improve walking in people with ataxia. You may qualify if you have trouble with balance or coordination while walking.
Dallas, TexasAges 18 years+ - NCT07653828Recruiting
Self-rehab after foot surgery via app
This trial tests if using a connected app to do self-guided rehab at home helps people recover better after bunion (hallux valgus) surgery. It may offer a convenient way to follow your exercises and track progress.
Saint-JeanAges 18–85 - NCT03594344Recruiting
Extra hyperbaric oxygen after leg amputation wounds heal
This study tests whether giving extra treatments with hyperbaric (pressure) oxygen after a leg amputation can improve healing or recovery. It’s meant for people whose amputation happened due to long-lasting infection or poor blood flow and who can attend follow-up visits.
OsloAges 18–90 - NCT03663790Recruiting
Gait retraining for knee osteoarthritis movement patterns
This trial tests whether a structured walking retraining program can improve how your leg moves if you have knee osteoarthritis. It may help reduce strain on your lower body during walking by changing walking technique.
Manassas, VirginiaAges 18–80 - NCT04232631Recruiting
Noninvasive tests to help wounds heal in diabetes
This study uses noninvasive (no major procedures) tests to better understand how diabetic foot ulcers or infections are healing. It may help doctors choose better ways to support wound healing in people with diabetes.
Dallas, TexasAges 18–89 - NCT04460573RecruitingPhase 2
Using a smart boot to improve diabetic foot offloading
This trial studies whether a special “smart boot” can help people with diabetic foot ulcers rest (offload) the affected foot as they should. Better offloading may improve healing by reducing pressure on the wound.
Downey, CaliforniaAges 18 years+ - NCT04547348RecruitingPhase 3
Denosumab for healing an acute Charcot foot in diabetes
This Phase 3 trial tests whether denosumab can improve healing and outcomes for people with an acute Charcot foot caused by diabetes-related nerve problems. You may be able to join if your Charcot foot is recently diagnosed and you meet specific safety and lab requirements.
AalborgAges 18–80 - NCT04594837Recruiting
Robotic ankle device therapy after stroke-related foot drop
This study tests a robotic ankle device to help improve walking in people after a stroke who still have foot drop (the foot doesn’t lift well). It may help strengthen or retrain walking patterns during recovery.
Baltimore, MarylandAges 18 years+
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Common questions
- Are there clinical trials for foot?
- Yes. Clin2 currently lists 292 recruiting foot studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a foot trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a foot trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.