Clinical trials
Fracture Lower Leg clinical trials
Below are recruiting fracture lower leg clinical trials, each written for real people, not researchers. We’re tracking 10 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07221019RecruitingPhase 4
Pain relief after leg injury: single shot vs. continuous numbing
This study compares two ways to manage pain after a leg injury: a single injection of a long-lasting numbing medicine (Exparel) versus a small tube that delivers numbing medicine for a few days (catheter). It is for people who have not used strong painkillers before and have a closed leg fracture.
Washington D.C., District of ColumbiaAges 18 years+ - NCT07561541RecruitingPhase 4
Extended Antibiotics for Diabetic Leg Fracture Surgery
This study tests whether taking antibiotics for a longer time helps prevent infections in people with poorly controlled diabetes who need surgery for a lower leg or foot fracture. Since diabetes makes infections more likely after surgery, extra antibiotics might reduce that risk.
Los Angeles, CaliforniaAges 18 years+ - NCT05699174RecruitingPhase 3
Compare two antibiotic routes for infected broken bones after surgery
This Phase 3 trial tests whether giving antibiotics by mouth (PO) works as well as giving antibiotics through a vein (IV) for an infected fracture that has not healed after prior surgery. It may help you understand which approach is safer and more effective for getting the bone to heal.
Indianapolis, IndianaAges 18 years+ - NCT03584815Recruiting
Test of physiotherapy versus surgery for exercise leg muscle pressure
This trial compares a physiotherapy program to a surgical procedure (fasciotomy) for chronic “compartment” pressure in the lower leg triggered by exercise. If you have symptoms that reliably come on with walking/running and improve with rest, the study may offer a structured way to find the best treatment for you.
Copenhagen, CopehagenAges 18–50 - NCT06636136Recruiting
Bone-anchored implant for below-knee amputation
This trial tests a metal implant that connects directly to your shin bone, replacing the need for a socket. It's for people with below-knee amputations who have trouble using a regular prosthetic leg.
Bethesda, MarylandAges 22–65 - NCT06963658Recruiting
Isometric Exercise and Pain Sensitivity in Chronic Low Back Pain
This study tests whether a simple, still (isometric) exercise can reduce how sensitive you are to pain. It is for adults with long-term low back pain who can safely do physical therapy exercises.
Bisha, 'Asir RegionAges 18 years+ - NCT07613333Recruiting
Exercise Program for New Mothers
This study tests an exercise program designed for women who have given birth within the past 2 years. Researchers want to learn how exercise affects energy levels and overall health after pregnancy.
Waukesha, WisconsinAges 18 years+ - NCT07613502Recruiting
Bio Leg: Advancing Mobility (BAM)
This study tests a new prosthetic leg designed to help people with above-knee amputations walk better. It may be a good fit if you already use a C-leg and can walk with a single point cane.
Jacksonville, FloridaAges 40–70 - NCT06370273RecruitingPhase 3
Blood thinners for leg casts after injury
This study tests whether taking a blood thinner (anticoagulant) pill can prevent dangerous blood clots in people who have a hard cast or brace on their leg after an injury. It compares two different blood thinners to see which works better.
Carshalton, SurreyAges 16 years+ - NCT05521958Enrolling by invitation
Gene activity study in severe leg muscle swelling after fracture
This study looks at gene activity (what genes are “turned on or off”) in the lower leg in people with acute compartment syndrome after a tibia (shin bone) injury. The goal is to better understand what is happening in the body and potentially guide future treatment decisions.
Salt Lake City, UtahAges 18–90
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Common questions
- Are there clinical trials for fracture lower leg?
- Yes. Clin2 currently lists 10 recruiting fracture lower leg studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a fracture lower leg trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a fracture lower leg trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.