Clinical trials
Chronic Wound of the Lower Limb (Leg Ulcer or Foot Ulcer) clinical trials
Below are recruiting chronic wound of the lower limb (leg ulcer or foot ulcer) clinical trials, each written for real people, not researchers. We’re tracking 177 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06810726RecruitingPhase 2
Platelet-rich fibrin gel for diabetic foot ulcers
This trial tests a special gel made from your own blood (platelet-rich fibrin, or PRF) to help heal diabetic foot ulcers that are not getting better with standard care. It may be an option if you have a mild-to-moderate ulcer on the bottom of your foot with good blood flow and no infection.
Corpus Christi, TexasAges 18–80 - NCT06939686Recruiting
Wound matrix study for diabetic foot ulcers
This study tests a new wound dressing made from pig tissue to help heal diabetic foot ulcers. It may help you if you have a foot sore that hasn't healed after 4 weeks of regular care.
Coconut Creek, FloridaAges 18 years+ - NCT06899113Recruiting
Comparing a new imaging device to standard blood flow tests
This trial tests a new camera that uses light to check blood flow in your legs. It compares the camera's results to standard tests like ABI and Doppler ultrasound to see if it works as well.
Lake Success, New YorkAges 18 years+ - NCT02280733Recruiting
Chronic wound registry for real-world care documentation
This study is a real-world registry that collects information about chronic wounds and ulcers as they’re treated in everyday settings. It may help improve how care is tracked and supported, even if you don’t get a new medicine from the study.
The Woodlands, TexasAges Any age - NCT05588583Recruiting
Tracking drainage from chronic leg or foot ulcers with a dressing
This study follows how much fluid (drainage) a chronic ulcer produces over time using a dressing called Mepilex Up. It may help clinicians better understand how this dressing manages “exuding” ulcers on the leg or foot.
Castro Valley, CaliforniaAges 18 years+ - NCT07541196Recruiting
PAW-Hydrogel treatment for long-lasting wound healing
This study tests a special gel called PAW-Hydrogel to help heal chronic wounds (wounds that have not closed after 3+ months). The gel may help wounds close faster by supporting the natural healing process.
Ocoyoacac, State of MexicoAges 18 years+ - NCT06939673Recruiting
Miro3D wound matrix for healing wounds and ulcers
This trial tests a special wound dressing called Miro3D that helps heal open wounds and ulcers. It may be a good option if you have a wound that is not healing, especially if it has tunnels or pockets under the skin.
Coconut Creek, FloridaAges 18 years+ - NCT07364630RecruitingPhase 4
Placental membrane trial for diabetic and venous leg ulcers
This study tests whether a special wound dressing made from human placental membrane can help heal diabetic foot ulcers or venous leg ulcers that did not close with standard care. It is for people who were in the BIOCAMP trial and whose ulcer remained open after 12 weeks of standard treatment.
Philidelphia, PennsylvaniaAges 18 years+ - NCT06236750Recruiting
Testing a human tissue wound covering for hard-to-heal ulcers
This study is testing a special wound covering made from donated human tissue (amnion/chorion membrane) to see if it helps heal stubborn diabetic foot ulcers or venous leg ulcers that haven't improved with standard care. The covering is placed on the wound to help it heal.
Kobe, HyōgoAges Any age - NCT07617961Recruiting
THERAVEX Spray for Wound and Ulcer Healing
This trial tests a topical spray treatment designed to help heal various types of skin wounds, including burns, pressure sores, and diabetic ulcers. The spray may help your wound heal faster and more effectively.
BarcelonaAges 18 years+ - NCT07632001Recruiting
Miro3D Wound Matrix for Diabetic Foot Ulcers
This trial tests a new wound-healing product called Miro3D to help diabetic foot ulcers heal better. You would receive this product along with standard wound care to see if it helps your ulcer close faster than standard treatment alone.
Phoenix, ArizonaAges 18 years+ - NCT07498218RecruitingPhase 1
Studying VELGRAFT for diabetic foot ulcers
This trial tests a new treatment called VELGRAFT, which is made from living cells, for diabetic foot ulcers that haven't healed with standard care. The goal is to see if it can help the wound close and heal more effectively.
Phoenix, ArizonaAges 18 years+ - NCT06328010Enrolling by invitation
Real-world data registry for wound care treatments
This study collects information on various wound types and how they respond to standard care. It aims to learn what works best for wounds that haven't healed after 4 weeks of treatment.
Scottsdale, ArizonaAges 18 years+ - NCT07414368Enrolling by invitation
StimLabs umbilical cord material for wound healing
This study looks at how a wound treatment made from donated human umbilical cord tissue works for both new and long-lasting wounds. The treatment is a dehydrated powder that is applied directly to the wound.
Bridgeport, ConnecticutAges 18 years+ - NCT07701590Recruiting
New wound dressings for hard-to-heal leg and foot ulcers
This study tests a special amniotic membrane wound dressing compared to a synthetic wound matrix for stubborn diabetic foot ulcers or venous leg ulcers. It may help if your wound has not been healing well for over a month.
San Diego, CaliforniaAges 18 years+ - NCT07116876Recruiting
Placental membrane vs standard care for diabetic foot ulcers
This study tests a special wound covering made from donated placental tissue to see if it helps diabetic foot ulcers heal better than usual care. It may be an option for people with diabetes who have a foot sore that hasn't healed after 30 days.
Tucson, ArizonaAges 21–80 - NCT07396376RecruitingPhase 1/Phase 2
Testing ELU42 spray for diabetic foot ulcers
This study tests a new topical spray (ELU42) to help heal diabetic foot ulcers. It may be a good option if you have a non-infected, non-ischemic ulcer and your blood sugar is reasonably controlled.
O'Fallon, IllinoisAges 18–75 - NCT05739149Recruiting
Ultrasound checks how chronic foot ulcers heal
This study tests a special ultrasound scan to see how chronic diabetic or venous foot ulcers are healing. The goal is to use the scan to better track wound improvement and guide care.
Rochester, MinnesotaAges 18 years+ - NCT04920253Recruiting
Testing a water-jet treatment to heal certain foot and leg wounds
This trial tests a new “micro water jet” device (Debritom+) to help heal specific hard-to-heal wounds in people who can attend frequent visits. If you qualify, you’ll be assigned to the device treatment or standard care and monitored to see how well the wound heals.
Bradenton, FloridaAges 18 years+ - NCT07046767Recruiting
Amnion grafts for slow-healing leg or foot ulcers
This trial tests if a special graft made from amniotic tissue can help heal chronic leg or foot ulcers that haven't improved much in the last month. It may be an option if you have a non-healing venous leg ulcer or diabetic foot ulcer that still shows some signs of healing.
Oxnard, CaliforniaAges 18 years+ - NCT07048054RecruitingPhase 1/Phase 2
Patch of fat cells for chronic leg ulcers
This trial tests a patch made from your own fat cells (called TrophiPatch) to see if it helps heal chronic leg ulcers. It is for people with venous leg ulcers or diabetic foot ulcers that are not healing well with standard care.
GenevaAges 18 years+ - NCT06384183Enrolling by invitation
Real-world fish skin graft registry study
This study tracks how well a fish skin graft (Kerecis) heals wounds in real patients. It helps doctors learn more about who benefits most from this treatment.
Sarasota, FloridaAges Any age - NCT03716167Recruiting
Near-infrared laser for healing and pain in leg vein ulcers
This study tests whether a near-infrared laser can improve healing and reduce pain in chronic venous leg ulcers. If you qualify, you may receive laser treatment and will be checked over time for wound healing and pain levels.
Winston-Salem, North CarolinaAges 18 years+ - NCT06383013RecruitingPhase 2
BB-101 for diabetic foot and leg ulcers
This trial tests a new medicine called BB-101 for diabetic ulcers on the lower leg or foot. The goal is to see if it helps these wounds heal faster.
TainanAges 20 years+
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Common questions
- Are there clinical trials for chronic wound of the lower limb (leg ulcer or foot ulcer)?
- Yes. Clin2 currently lists 177 recruiting chronic wound of the lower limb (leg ulcer or foot ulcer) studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a chronic wound of the lower limb (leg ulcer or foot ulcer) trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a chronic wound of the lower limb (leg ulcer or foot ulcer) trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.