Clinical trials
Lower Extremity Fracture clinical trials
Below are recruiting lower extremity fracture clinical trials, each written for real people, not researchers. We’re tracking 26 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07323147Enrolling by invitation
Robot-assisted walking therapy for hip fracture recovery
This study tests whether a robot suit can help older adults walk better after hip fracture surgery. If you are 65 or older and had surgery for a broken hip from a minor fall, you may be able to join.
Beijing, Beijing MunicipalityAges 65–100 - NCT07314450Recruiting
Pain and sedation for fracture and dislocation treatment in the ER
This study tests how well pain and sedation medicines work in the emergency department when treating adults with certain broken bones or dislocated joints that need to be set or casted. It aims to see which approach is safest and most comfortable for patients.
Holbæk, Region SjællandAges 18 years+ - NCT07217626RecruitingPhase 4
Nerve blocks before leg fracture surgery in older adults
This trial tests whether giving a nerve block (medicine to numb the leg) before surgery helps older adults recover better from a broken leg bone. If you are 50 or older and need surgery for a specific type of leg fracture, you may be eligible.
Baltimore, MarylandAges 50 years+ - NCT06496035Recruiting
Blood flow training for leg fracture recovery
This study tests whether a special exercise method called blood flow restriction training helps people heal faster after a broken shinbone (tibia). It might improve strength and recovery during physical therapy.
Denver, ColoradoAges 18–100 - NCT06293469Recruiting
Speeding up flap surgery for severe leg injuries
This trial tests whether performing flap surgery sooner after a severe leg injury below the knee leads to better outcomes. If you have an open fracture or dislocation that needs a flap, you may be able to join.
Sacramento, CaliforniaAges 18 years+ - NCT05699174RecruitingPhase 3
Compare two antibiotic routes for infected broken bones after surgery
This Phase 3 trial tests whether giving antibiotics by mouth (PO) works as well as giving antibiotics through a vein (IV) for an infected fracture that has not healed after prior surgery. It may help you understand which approach is safer and more effective for getting the bone to heal.
Indianapolis, IndianaAges 18 years+ - NCT07552766RecruitingPhase 4
Lidocaine infusion to reduce opioid use in arm fracture surgery
This study tests whether giving a pain-relieving medication called lidocaine through an IV during arm fracture surgery can reduce how much opioid pain medication (like morphine) children need after surgery. The goal is to help manage pain better while using fewer opioids.
Wilmington, DelawareAges 3–18 - NCT06098157Recruiting
Non-healed broken bones in arm or leg after surgery
This is a registry study that collects information from people who have had surgery for a broken arm or leg bone that did not heal on its own. It helps doctors better understand why some bones don't heal and how to improve treatment.
Tübingen, Baden-WurttembergAges 18 years+ - NCT05381818Recruiting
Breathing muscle training before joint surgery
This trial tests whether strengthening breathing muscles before total joint surgery can lower the chance of lung complications after the operation. It may help people who already have breathing problems or a history of smoking.
Jacksonville, FloridaAges 18–100 - NCT07374835Enrolling by invitation
Weight-based treatment for leg swelling after gynecologic cancer surgery
This study tests a treatment plan based on your body mass index (BMI) to help reduce leg swelling (lymphedema) that started within 2 years after gynecologic cancer surgery. It aims to find a more personalized way to manage this condition.
Wuhan, HubeiAges 18–75 - NCT07561541RecruitingPhase 4
Extended Antibiotics for Diabetic Leg Fracture Surgery
This study tests whether taking antibiotics for a longer time helps prevent infections in people with poorly controlled diabetes who need surgery for a lower leg or foot fracture. Since diabetes makes infections more likely after surgery, extra antibiotics might reduce that risk.
Los Angeles, CaliforniaAges 18 years+ - NCT06990555Recruiting
Cast art for kids with broken bones
This study looks at using a special cast art program for children with broken arms or legs. It aims to see if decorating casts can make the experience better for kids and their families.
Portsmouth, VirginiaAges 5–18 - NCT07749612Recruiting
Robotic arm trainer for stroke and brain injury recovery
This trial tests a robotic device that helps people move their arms and hands during rehabilitation after a stroke, brain injury, or spinal cord injury. The goal is to improve arm function and make daily tasks easier.
DhakaAges 18–60 - NCT07749625Recruiting
Robotic arm training for recovery after stroke or injury
This study tests whether a robotic arm trainer can help improve arm movement and function in people with conditions like stroke, spinal cord injury, or brain injury. It may help you regain strength and control in your arm.
DhakaAges 18–60 - NCT05845021Recruiting
Screening and referral for bone health after hip or knee surgery
This study looks at a simple plan for surgeons to identify people with low bone strength (osteoporosis) and refer them for bone health care after hip or knee replacement surgery. It may help you get evaluated and treated earlier if you have osteoporosis.
Columbia, MarylandAges 50 years+ - NCT05521958Enrolling by invitation
Gene activity study in severe leg muscle swelling after fracture
This study looks at gene activity (what genes are “turned on or off”) in the lower leg in people with acute compartment syndrome after a tibia (shin bone) injury. The goal is to better understand what is happening in the body and potentially guide future treatment decisions.
Salt Lake City, UtahAges 18–90 - NCT07863115Recruiting
Preventing blood clots after leg injury with a cast
This study looks at a simple checklist to see who is at risk for blood clots after a leg injury that requires a cast or brace. It also checks how well people follow blood-thinning medication to prevent these clots.
MonastirAges 18 years+ - NCT07834333Recruiting
Brain stimulation to help arm and leg recovery after stroke
This trial tests a non-invasive brain stimulation technique called theta burst stimulation to see if it can improve arm and leg function in people who recently had a stroke. It may help with movement recovery in the first few months after stroke.
Ankara, YenimahalleAges 45 years+ - NCT06673823Recruiting
Mirror therapy for leg movement in children with CP
This study tests whether mirror therapy—where your child watches the reflection of their good leg moving—can help improve movement in their affected leg. It is designed for children with cerebral palsy who have mild to moderate leg stiffness.
Lahore, Punjab ProvinceAges 6–12 - NCT07613333Recruiting
Exercise Program for New Mothers
This study tests an exercise program designed for women who have given birth within the past 2 years. Researchers want to learn how exercise affects energy levels and overall health after pregnancy.
Waukesha, WisconsinAges 18 years+ - NCT06653855Recruiting
Cupping for leg stiffness and movement after stroke
This study tests if cupping therapy can reduce leg stiffness and improve movement in people recovering from a stroke. You must be getting rehab at a specific clinic in Joliet.
Joliet, IllinoisAges 30–80 - NCT06343688Recruiting
How ankle braces affect motor skills in CP
This study tests how wearing special ankle braces (called DAFOs) right away affects movement and balance in children with spastic diplegic cerebral palsy. It aims to see if the braces make it easier to walk and stand.
BoluAges 4–15 - NCT07319403Recruiting
Hip or ankle exercises for ankle instability in athletes
This study compares two exercise programs—one focusing on the hip, the other on the ankle—to see which is better for improving leg function in athletes with chronic ankle instability. The goal is to help athletes regain strength and confidence in their ankle.
Ankara, ÇankayaAges 18–40 - NCT07202780Enrolling by invitation
MS and Muscle Strength in Breathing and Legs
This study looks at how MS affects the strength of your breathing muscles and leg muscles. If you join, you will have tests to measure your muscle strength, walking ability, and fatigue. This may help doctors understand how to better treat MS-related weakness.
Gaziantep, şehitkamilAges 18–50
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Common questions
- Are there clinical trials for lower extremity fracture?
- Yes. Clin2 currently lists 26 recruiting lower extremity fracture studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a lower extremity fracture trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a lower extremity fracture trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.