Clinical trials
Frailty clinical trials
Below are recruiting frailty clinical trials, each written for real people, not researchers. We’re tracking 245 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07727876Recruiting
Ready for safe cancer treatment: A program to improve surgery recovery
This trial tests a comprehensive program to help patients prepare for and recover from cancer surgery. It aims to reduce complications and improve outcomes.
Wroclaw, Lower Silesian VoivodeshipAges 18 years+ - NCT07731529Enrolling by invitation
Exercise program for people 90 and older at home
This trial tests a home-based exercise program designed to improve strength, balance, and thinking skills in people aged 90 and older. It might help you stay active and independent.
Porto Alegre, Rio Grande do SulAges 90 years+ - NCT07723339Enrolling by invitation
Exercise program for people aged 100 and older
This trial studies whether a supervised physical exercise program can improve the health and daily functioning of centenarians (people aged 100 or older). If you are at least 100 years old and can stand and move around with little help, this program might help you stay active and independent.
Pamplona, NavarreAges 100 years+ - NCT07709975Recruiting
Pain relief and early movement for older ICU patients
This study tests different ways to manage pain and help older patients get moving again sooner after major surgery. If you are 65 or older and in the ICU, this trial may help you recover more comfortably and quickly.
Istanbul, IstanbulAges 65 years+ - NCT07707297Recruiting
Study of Navarre's Centenarians (born 1926-1927)
This study is for people aged 100 and older in Navarre, Spain. It aims to learn more about what contributes to a long and healthy life.
Pamplona, NavarreAges 100 years+ - NCT07677072Recruiting
Studying a blood protein to detect hidden bone fragility
This study looks at a protein called lumican in the blood to see if it can help find women who have fragile bones even if their bone density test looks normal. It's for postmenopausal women who are already getting a bone density scan as part of their routine care.
Küçükçekmece, IstanbulAges 45 years+ - NCT07677319Recruiting
Heart surgery after age 75: a study on recovery
This study looks at how well people aged 75 and older recover after emergency heart surgery. It uses a special test to measure frailty and quality of life for one year after surgery.
Bordeaux, FranceAges 75 years+ - NCT07669168Recruiting
Health study comparing usual care vs. extra support
This study looks at whether adding extra health support helps people stay healthier over time. You would be followed for a while and asked to share how you are doing.
Boulder, ColoradoAges 18 years+ - NCT07646782Recruiting
Human Observatory Study: Aging and Longevity Research
This study observes how people age over time to better understand what helps people live longer and healthier lives. You'll share health information through surveys or online screening, and researchers will track changes in your health and wellbeing.
Boulder, ColoradoAges 18 years+ - NCT07652892Recruiting
Fatty Liver, Memory, and Health in Men and Women
This study looks at how fatty liver disease (related to metabolism) affects memory, strength, and quality of life—especially comparing men and women. It helps understand why some people with fatty liver feel more tired or have trouble thinking clearly.
Barcelona, BarcelonaAges 20–80 - NCT07642765Recruiting
Frailty Score and Blood Pressure Changes During Surgery
This study looks at a simple scoring system (EASIX) that predicts whether older or frail patients will experience dangerous blood pressure drops when anesthesia is given before surgery. Understanding this risk might help doctors better protect vulnerable patients during their operations.
KonyaAges 18 years+ - NCT05554003RecruitingPhase 2
Low-grade neuroendocrine tumors: metronomic temozolomide for frail patients
This Phase 2 study tests a gentler, steady schedule of temozolomide in people with advanced low-grade neuroendocrine neoplasms who are “unfit” for stronger treatments. The goal is to shrink or control the cancer while being safer for people with weaker health or organ function.
MilanAges 18 years+ - NCT06692855Recruiting
Frailty score's role in predicting outcomes for cardiogenic shock
This study looks at whether a simple frailty score (measuring how well someone can function) can help predict recovery for people hospitalized with cardiogenic shock, a condition where the heart suddenly can't pump enough blood.
StrasbourgAges 18 years+ - NCT04926597Recruiting
Extra nutrition after hospital discharge for higher-risk patients
This study looks at whether continuing nutritional support after you leave the hospital can reduce death risk and help you recover better—like improving strength, frailty, and daily functioning. It targets people who are at higher risk of poor nutrition during/after their hospital stay.
BarcelonaAges 18 years+ - NCT07627919Recruiting
Strength training and high-protein diet for frail older women
This study tests whether combining resistance exercises with a protein-rich diet can improve muscle strength and overall function in older women with weak muscles. You would attend supervised workouts and follow a specific eating plan for several weeks.
El-Sheikh Zayed CityAges 60–70 - NCT06671353Recruiting
Video decision support for advance care planning in frail older adults
This trial tests if watching a video helps older adults with frailty make informed decisions about future medical care. You may be able to join if you are 65 or older, have been diagnosed with frailty, and can watch a video and sign a consent form.
TaipeiAges 65 years+ - NCT02856620Recruiting
Study heart function and frailty in people with aortic valve narrowing
This study looks at how heart mechanics, blood markers, and frailty relate to symptoms and heart measurements in people with aortic stenosis (a stiff, narrowed heart valve). It may help doctors better understand who is at higher risk and how disease changes over time.
Montreal, QuebecAges 18 years+ - NCT06706492Recruiting
Muscle oxygen and frailty in kidney transplant patients
This study looks at how well muscles use oxygen and how frailty affects kidney transplant recipients, especially those with weak breathing muscles. It may help understand why some patients feel more tired or weak after transplant.
AnkaraAges 18–65 - NCT07597850RecruitingPhase 2
TCM formula versus HMB supplement for muscle strength in older adults
This study compares a traditional Chinese medicine formula with HMB (a muscle-building supplement) to see which helps preserve muscle strength and bone health in adults aged 65 and older who are starting to show signs of frailty. Both treatments aim to help you stay stronger and more active as you age.
TaipeiAges 65 years+ - NCT04906759Recruiting
Meal delivery plus exercise for homebound frail adults
This study tests whether providing meal delivery and an exercise plan can help people who are homebound and frail stay stronger. It is mainly for adults who can safely participate and follow simple instructions.
Houston, TexasAges 60 years+ - NCT07573995Recruiting
Breathing and muscle training for frailty in older adults
This study tests a training program that combines breathing exercises with blood flow restriction (using bands to reduce blood flow in the arms or legs) to see if it improves strength and daily function in older adults who are frail. It may help you feel stronger and more independent.
TaipeiAges 65 years+ - NCT07563777Recruiting
Long-term study of human aging and health
This is a long-term research study that follows people over time to understand how humans age. Researchers will collect information about your health and lifestyle to learn what helps people stay healthier as they get older.
Boulder, ColoradoAges 18 years+ - NCT07561138Recruiting
Nutrition and Exercise Training Before Liver Transplant
This study tests whether eating better and doing gentle exercise before your liver transplant can help you stay healthier and recover better after surgery. You'll work with a nutrition expert and exercise specialist to prepare your body for transplant.
Athens, AtticaAges 18–70 - NCT05946109Recruiting
Exercise program for frail older adults over 70
This trial studies whether a structured exercise program can improve health and function in frail adults age 70 and older. It may help you build strength, energy, and mobility if you meet frailty and safety requirements.
Brussels, Brussels CapitalAges 70 years+
Hear when a new Frailty trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.
Common questions
- Are there clinical trials for frailty?
- Yes. Clin2 currently lists 245 recruiting frailty studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a frailty trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a frailty trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.