Clinical trials
Frailty clinical trials
Below are recruiting frailty clinical trials, each written for real people, not researchers. We’re tracking 265 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07086716Recruiting
Frailty study for hip or knee replacement patients
This study looks at frailty in people who have had a planned hip or knee replacement. It aims to understand how frailty affects recovery.
Rovato, BSAges 18 years+ - NCT06706492Recruiting
Muscle oxygen and frailty in kidney transplant patients
This study looks at how well muscles use oxygen and how frailty affects kidney transplant recipients, especially those with weak breathing muscles. It may help understand why some patients feel more tired or weak after transplant.
AnkaraAges 18–65 - NCT06216002Recruiting
Residual paralysis after cancer surgery in frail patients
This trial checks how often muscle relaxant effects linger after gynecologic cancer surgery, especially in frail patients. It uses a nerve stimulator to measure muscle function after surgery.
Bangkok, BangkokAges 18 years+ - NCT06363942Recruiting
Video exercise program for fall prevention in frail older adults
This trial tests a personalized video-based exercise program to help older adults who are frail or pre-frail prevent falls. It may be a good fit if you are relatively healthy aside from frailty concerns.
Montreal, QuebecAges 70 years+ - NCT07572851Enrolling by invitation
Exercise Program for Preventing Falls in Older Adults
This study looks at how an exercise and wellness program helps older adults stay stronger and reduce their risk of falling. Researchers will track changes in your physical function and balance over time.
A Lama, PontevedraAges 70 years+ - NCT06628895Recruiting
Modified Poco-Poco exercise for pre-frailty
This study tests whether a special exercise routine called Modified Poco-Poco can improve frailty and certain biological markers (DNA changes, GDF15, and Lamin A). It may help people who are beginning to feel weaker and want to try a gentle exercise program.
Bandung, West JavaAges 60 years+ - NCT06141798Recruiting
Dialysis Frequency for Older Adults
This trial compares two versus three times weekly dialysis for people aged 60 or older who are just starting maintenance hemodialysis. It aims to find the best schedule for older adults with end stage kidney disease.
Bucheon-siAges 60 years+ - NCT06844318Recruiting
IBD treatment and frailty in patients over 60
This study looks at how inflammatory bowel disease (IBD) activity affects frailty in people over 60. It tests whether starting or changing medication for active IBD can help understand and manage frailty.
Vitoria-Gasteiz, AlavaAges 60 years+ - NCT03430037Enrolling by invitationPhase 2
Fisetin study to reduce frailty and inflammation in older women
This Phase 2 trial tests whether fisetin, a supplement, can reduce frailty and inflammation in postmenopausal women age 70 and older. If it works, it may help older adults feel stronger and have healthier body signals related to aging and inflammation.
Rochester, MinnesotaAges 70 years+ - NCT07059286Enrolling by invitation
Pregnancy, Baby Brain Scans, and Child Development Study
This study looks at how a mother's health and experiences during pregnancy may affect her baby's brain growth and early development. You and your baby would have special MRI brain scans, fill out some questionnaires, and then your child's development would be followed until they are 6 years old.
Milan, MIAges 18 years+ - NCT07486661Recruiting
Preventing frailty in people with HIV aged 65-75
This study aims to help people with HIV between the ages of 65 and 75 stay healthy and avoid becoming frail as they age. It tests a program to prevent frailty and see if it works.
BrusselsAges 65–74 - NCT06925880Recruiting
Can creatine help seniors recover strength after knee replacement?
This trial tests if taking creatine supplements can help people aged 65+ rebuild muscle mass and strength more quickly after total knee replacement surgery. Participants will take creatine during their standard outpatient rehab program.
Mataró, BarcelonaAges 65 years+ - NCT06874413Enrolling by invitation
Exercise program for frail older adults before hernia surgery
This study tests whether a supervised exercise program before hernia repair surgery helps frail older adults recover better. The program includes physical exercises and breathing muscle training.
Greenville, South CarolinaAges 65 years+ - NCT06516198Recruiting
Ear acupressure before lung surgery
This study tests whether ear acupressure can help people get stronger before major lung surgery. You'll wear small seeds on your ears and do exercise prehabilitation.
Chicago, IllinoisAges 50 years+ - NCT06379009Recruiting
Home exercise program for kidney transplant recipients
This trial tests a home-based exercise program for people who have recently had a kidney transplant. It aims to help you improve your physical function and recovery after surgery.
OsloAges 18 years+ - NCT06113016RecruitingPhase 2
Preventing frailty with fisetin and exercise in breast cancer survivors
This study tests whether adding a supplement called fisetin to an exercise program can help prevent frailty in women who have finished chemotherapy for early-stage breast cancer. If you are postmenopausal, have completed chemo within the last year, and can walk a certain distance, you may qualify.
Alhambra, CaliforniaAges Any age - NCT06036615Recruiting
Exercise training for frailty and fall risk in heart failure
This trial tests whether a supervised exercise program can reduce frailty and fall risk in people with chronic heart failure, and what happens when training stops. It may help you feel stronger and more stable.
Thessaloniki, ThermiAges 18–100 - NCT06645847Recruiting
Ketone drink for walking and strength in older adults
This study tests whether a special ketone drink can help older adults who are starting to feel frail (slower walking, less energy). You would be assigned to one of several groups, and researchers will check if the drink improves your strength and daily function.
Novato, CaliforniaAges 65 years+ - NCT06100445Recruiting
Exercise engagement in people over 60 at fall risk
This study looks at how to help people over 60 who are at risk of falling get more exercise. It focuses on falls caused by muscle or balance problems, and aims to improve engagement in physical activity.
Blackburn, LancashireAges 60–95 - NCT07677319Recruiting
Heart surgery after age 75: a study on recovery
This study looks at how well people aged 75 and older recover after emergency heart surgery. It uses a special test to measure frailty and quality of life for one year after surgery.
Bordeaux, FranceAges 75 years+ - NCT07465159Recruiting
Prehabilitation for frail patients before hip or knee replacement
This study tests whether a 'prehabilitation' program (tailored exercise and nutrition support before surgery) helps older patients who are frail recover better after hip or knee replacement. Participants will be randomly assigned to either the prehabilitation group or the usual care group.
ReykjavikAges 70 years+ - NCT07184333Recruiting
Home-based care training for nursing and physio students
This trial trains nursing and physiotherapy students to provide home-based care for older adults. It aims to improve teamwork and care for seniors with mild impairments.
Hong KongAges 18 years+ - NCT07490184Recruiting
Heart check vs frailty score for hip surgery
This trial compares two ways to evaluate older adults before hip surgery to see which better predicts recovery. It may help doctors choose the safest approach for you.
Dallas, TexasAges 60 years+ - NCT07732530Recruiting
Acupoint Stimulation and Exercise for Pre-Frail Older Adults
This study tests whether combining acupoint stimulation (a type of pressure on specific body points) with exercise can help older adults who are starting to become frail. It aims to improve strength and daily function.
TainanAges 50 years+
Hear when a new Frailty trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.
Common questions
- Are there clinical trials for frailty?
- Yes. Clin2 currently lists 265 recruiting frailty studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a frailty trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a frailty trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.