Clinical trials
Frailty clinical trials
Below are recruiting frailty clinical trials, each written for real people, not researchers. We’re tracking 245 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07525583Recruiting
Screening and Preventing Decline in Older Adults' Physical Ability
This study helps doctors identify older adults at risk of losing physical strength and independence, and tests ways to prevent that decline. You'll be screened for your overall fitness and given guidance to stay healthy as you age.
SingaporeAges 60 years+ - NCT07531836Recruiting
Prehabilitation for older adults having breast cancer surgery
This trial tests a program of exercise and support before breast cancer surgery to help older patients recover better. It aims to improve strength and overall health so you can get back to your daily life sooner after the operation.
Pamplona, NavarreAges 65 years+ - NCT07513701Recruiting
Building Strength and Balance in Older Adults
This study tests whether a home-based exercise program can help older adults who are experiencing physical weakness improve their strength, balance, and overall resilience. You'll do exercises online at home over several months to see if this approach helps you stay independent and active.
Hong Kong, Hong KongAges 60–90 - NCT07505758Recruiting
Recovery after surgery in adults 80 and older
This study looks at how well adults aged 80 or older recover after planned surgery that requires an overnight hospital stay. The goal is to understand recovery using a simple questionnaire.
Barcelona, BarcelonaAges 80 years+ - NCT07497334Recruiting
Improving functional outcomes in cognitively frail older adults
This study tests a program combining cognitive exercises, physical activity, and brain stimulation to improve daily function and thinking in older adults with mild cognitive or physical frailty. The goal is to help you stay independent and improve your quality of life.
Hong KongAges 60–90 - NCT07490184Recruiting
Heart check vs frailty score for hip surgery
This trial compares two ways to evaluate older adults before hip surgery to see which better predicts recovery. It may help doctors choose the safest approach for you.
Dallas, TexasAges 60 years+ - NCT07488364Recruiting
Understanding frailty in Parkinson's disease
This study looks at why some people with Parkinson's disease become physically frail. It aims to find factors that may help predict or prevent frailty.
Istanbul, TurkeyAges 40–85 - NCT07486661Recruiting
Preventing frailty in people with HIV aged 65-75
This study aims to help people with HIV between the ages of 65 and 75 stay healthy and avoid becoming frail as they age. It tests a program to prevent frailty and see if it works.
BrusselsAges 65–74 - NCT07475767Recruiting
Ultrasound and nutrition in surgical ICU patients
This trial uses ultrasound to check muscle and body composition in patients recovering from surgery in the ICU. It also looks at how nutrition affects recovery, so you may be asked about your diet.
OsijekAges 18 years+ - NCT07464106Recruiting
Tricuspid valve treatment study for older adults
This study tests if a less invasive tricuspid valve repair or replacement can protect kidney function and improve physical activity in older adults with severe tricuspid valve leakage.
StuttgartAges 18 years+ - NCT07465159Recruiting
Prehabilitation for frail patients before hip or knee replacement
This study tests whether a 'prehabilitation' program (tailored exercise and nutrition support before surgery) helps older patients who are frail recover better after hip or knee replacement. Participants will be randomly assigned to either the prehabilitation group or the usual care group.
ReykjavikAges 70 years+ - NCT07463352Recruiting
Pre-surgery nutrition for frail seniors with hip fractures
This study tests if giving a special protein drink before surgery helps frail older adults with a broken hip recover better. It might reduce complications after surgery.
DüzceAges 65 years+ - NCT07454616Recruiting
Supplement and exercise study for pre-frail adults
This study tests whether a special nutrient supplement combined with a simple exercise routine can improve health markers linked to living longer. It is designed for adults who are starting to feel less strong or energetic but are not yet frail.
SingaporeAges 50–80 - NCT07441382Recruiting
Comparing treatments for frail older adults with atrial fibrillation
This study tests whether combining a heart procedure (catheter ablation) with a device to close the left atrial appendage (LAAO) is safer or better than blood thinners alone for frail patients 75 years or older with atrial fibrillation and high stroke risk. It aims to find a treatment that reduces stroke while lowering bleeding risks.
Guangzhou, GuangdongAges 75 years+ - NCT07432009Recruiting
Hip replacement and confusion risk in older adults
This study looks at whether older adults who get a hip replacement may experience confusion after surgery. It aims to find factors that might help prevent or reduce this confusion.
BrnoAges 65 years+ - NCT06819982Recruiting
Home support with occupational therapy for older adults
This trial tests whether having an occupational therapist help you at home with assistive devices can keep you independent longer. It is for people 65 or older who are starting to feel a bit frail or at risk of frailty.
YvoirAges 65 years+ - NCT07414095Recruiting
Frailty assessment before liver transplant and outcomes
This study looks at how frail liver transplant candidates are before surgery and whether that affects their recovery afterward. Participants will complete simple physical and mental tasks to help doctors better understand their overall health before the transplant.
IzmirAges 18–65 - NCT06040801Recruiting
Geriatric care for older adults with advanced stomach, bile duct, or pancreatic cancer
This study tests a special geriatric (older-adult) care program for people over 65 with advanced stomach, bile duct, or pancreatic cancer who are receiving palliative chemotherapy. The goal is to see if extra support from a geriatric team can help improve quality of life and treatment outcomes.
Taoyuan, TaiwanAges 65 years+ - NCT07392944Recruiting
Exercise program for older adults in nursing homes
This trial tests a multicomponent exercise program for older adults living in nursing homes. The goal is to see if it improves physical function, thinking skills, and reduces falls risk.
PortoAges 65 years+ - NCT06836167Recruiting
Integrated care for frail older adults
This study tests a program called +AGIL Barcelona that provides integrated care for older adults living at home who show signs of frailty. It aims to help them stay independent and healthy.
BarcelonaAges 65 years+ - NCT06839040Recruiting
Exercise and education program to reduce falls and urine leakage
This study tests a program of exercises and education to help older women reduce their risk of falling and improve bladder control. If you are a woman aged 60–80 with urine leakage and do little exercise, this program might support your strength and confidence.
Valencia, ValenciaAges 60–80 - NCT07373119Enrolling by invitation
Frailty reduction in stable heart disease patients
This study tests a program to reduce frailty in older adults with stable coronary artery disease. The goal is to improve strength and well-being in people who are not having recent heart problems.
Barcelona, Select...Ages 70 years+ - NCT07366684Recruiting
Heart attack study for adults 75 and older
This study looks at how frailty and other health factors affect recovery in people 75 and older who have had a heart attack or unstable chest pain. It may help doctors better understand who is at higher risk and how to improve care for older adults.
NišAges 75 years+ - NCT07355413Recruiting
Frailty and health in older adults with HIV in West Africa
This study looks at how frailty (weakness) and other age-related health issues affect older adults living with HIV in West Africa. By comparing those with and without HIV, researchers hope to better understand the care needs of this group.
Bobo-DioulassoAges 60 years+
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Common questions
- Are there clinical trials for frailty?
- Yes. Clin2 currently lists 245 recruiting frailty studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a frailty trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a frailty trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.