Clinical trials
Functionality clinical trials
Below are recruiting functionality clinical trials, each written for real people, not researchers. We’re tracking 2,564 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT04918329Recruiting
Digestive symptom check-in study for adults
This study follows adults with long-lasting “functional” digestive symptoms as part of routine care. It may help researchers better understand these conditions and improve how they are managed.
RouenAges 18 years+ - NCT05049317Recruiting
Check urinary and sexual function after rectal cancer surgery
This study looks at how a specific rectal surgery (laparoscopic total mesorectum excision) affects urinary and sexual function after the operation. It may help patients by tracking what to expect and which factors relate to better recovery.
Wuhan, HubeiAges 18–70 - NCT05051059Recruiting
Life quality check after leg sarcoma surgery
This study checks how people with leg sarcoma are functioning and how satisfied they are with their quality of life after treatment. It mainly looks at patients at least one year after limb-sparing surgery, to understand long-term effects and support.
Leuven, Vlaams-BrabantAges 18–95 - NCT05147649Recruiting
Brain scan study in severe sleep apnea without CPAP
This trial uses a specialized brain scan (MRI) to study people with severe obstructive sleep apnea who are not using CPAP. It also compares them with people who do not have sleep apnea to understand how brain function differs.
ReimsAges 18–75 - NCT05185609Recruiting
Tests anal function in people with inflammatory bowel disease
This study checks how well the anal area works in people with inflammatory bowel disease (IBD), even when your bowel disease is “in remission” but you may still have symptoms. It may help doctors better understand the cause of ongoing problems and guide future care.
ÖrebroAges 18–65 - NCT05193136Recruiting
Testing sleep and exercise effects on strength and thinking in lung disease
This trial studies whether improving sleep habits can help people with lung conditions like COPD or IPF maintain muscle strength and thinking (cognitive function). It may help by addressing sleep quality and related health factors, but eligibility depends on your current diagnoses and treatments.
Jōyō, KyotoAges 20 years+ - NCT05339438Recruiting
Brain scan mapping before epilepsy surgery
This study uses a special MRI scan to map parts of the front-temporal brain in people with drug-resistant epilepsy who may need surgery. The goal is to better plan surgery by showing which brain areas are involved.
NancyAges 18 years+ - NCT05359796Recruiting
Study of long-term type 1 diabetes symptoms and characteristics
This study looks at what day-to-day health and medical features are like in people who have had type 1 diabetes for many years. It may help researchers better understand long-term needs in type 1 diabetes and guide future care.
Changsha, HunanAges Any age - NCT05389787Recruiting
Brain stimulation to improve thinking in schizophrenia
This pilot study tests whether stimulating the cerebellum (a part of the brain) using TMS can improve brain function and thinking in people with schizophrenia. If you qualify, you may receive TMS and undergo brain/cognitive assessments to see whether it helps.
New York, New YorkAges 18–60 - NCT05391737Recruiting
Study of fluid in the lungs after open-water swimming
This study looks at what happens in the lungs after open-water swimming. It may help doctors better understand and recognize “swimming-induced lung fluid,” especially by using lung ultrasound when symptoms happen.
FalunAges 18 years+ - NCT05447273Recruiting
MRI to plan less invasive surgery for penile cancer
This trial studies how functional MRI scans (a special MRI that shows how tissues work) can help doctors plan surgery for newly diagnosed penile squamous cell cancer. It may help more people get organ-sparing surgery, which aims to remove the cancer while preserving as much function as possible.
OsloAges Any age - NCT05480982Recruiting
Cognitive functional therapy versus Pilates for low back pain
This study compares two exercise-based approaches—cognitive functional therapy and Pilates—to help reduce chronic low back pain in older adults. It may help by improving how you move and manage pain, not just stretching muscles.
Rio de Janeiro, Rio de JaneiroAges 65 years+ - NCT05525845Recruiting
Brain scan study of how the body controls eating
This study uses an MRI brain scan to understand why you feel hungry, satisfied, or “pulled” to eat, and how your body’s internal balance affects food intake. It may help researchers learn more about eating regulation, which could guide future treatments.
Rochester, MinnesotaAges 21–50 - NCT05587127Recruiting
CBT therapy for eating anxiety in functional stomach pain
This trial tests an “exposure-based” type of cognitive behavioral therapy (CBT) to help people with functional dyspepsia (stomach discomfort after eating) who avoid or restrict food. The goal is to reduce food fear and improve eating and weight, after other medical causes have been ruled out.
Boston, MassachusettsAges 18 years+ - NCT05595577Recruiting
Personalized exercise program to improve fitness during cancer care
This trial tests whether a tailored, home-based exercise plan can improve exercise capacity (how far and how safely you can be active) in people receiving cancer treatments that may affect the heart. It may help you build safer stamina while monitoring your heart health.
Winston-Salem, North CarolinaAges 18–85 - NCT05644171Recruiting
Epidural spinal stimulation for chronic spinal cord injury recovery
This trial tests whether a stimulating device placed near the spinal cord can help improve movement and rehabilitative function in people with long-term spinal cord injuries. It may help some patients strengthen function, but only if they meet specific injury and health requirements.
SingaporeAges 21 years+ - NCT05649930Recruiting
Power training for tight calf muscles in children with spastic paresis
This trial tests whether a specific exercise program that strengthens leg muscle power can improve calf muscle length and strength in children with spastic paresis (stiffness from the brain or nerves). If it works, it may help children move more easily and build stronger calves.
AmsterdamAges 4–18 - NCT05653973RecruitingEarly Phase 1
Testing aspirin’s effects on blood vessel function after pregnancy
This early study looks at how taking aspirin (or not) affects how well blood vessels work after pregnancy. It may help researchers understand differences in vascular health after normal pregnancies versus preeclampsia (a pregnancy blood pressure complication).
Iowa City, IowaAges 18–50 - NCT05694039Recruiting
Track thinking changes in older adults with hearing loss
This study follows older adults who have age-related hearing loss to see whether wearing hearing aids helps protect thinking and memory over time. You may be included if your hearing loss is the type that hearing aids can usually improve and if your thinking test scores suggest mild cognitive difficulties.
Guangzhou, GuangdongAges 60–85 - NCT05698576Recruiting
Laser treatment through the skin for men with prostate cancer
This trial tests a laser procedure done through the skin between the scrotum and anus, guided by MRI and ultrasound, for men with certain prostate cancer types. It aims to heat and treat prostate cancer while checking safety and outcomes over follow-up visits.
Hialeah, FloridaAges 50–80 - NCT05719415Recruiting
Testing balloon treatment effects on lung blood-vessel surface area
This study looks at how a procedure called balloon pulmonary angioplasty changes measurements in lung blood vessels in people with chronic thromboembolic pulmonary hypertension. It may help doctors understand what changes the treatment makes and why.
Montreal, QuebecAges 18–75 - NCT05723913Recruiting
Test functional foods on blood sugar and gut bacteria
This study looks at how eating specific functional foods affects blood sugar after meals and changes in gut bacteria. It may help people understand ways to support healthy blood sugar and digestion, but it’s not for people with diabetes.
Mexico City, Mexico CityAges 18–60 - NCT05756894Recruiting
Stimulation therapy to improve breathing after spinal cord injury
This trial studies a neurostimulation approach to help breathing problems after a spinal cord injury. You may be able to join if you have a certain type and level of spinal cord injury and breathing weakness, and you can safely attend study visits with caregiver support.
Chicago, IllinoisAges 18–85 - NCT05769036Recruiting
Biventricular vs left bundle pacing for heart failure outcomes
This trial compares two types of heart pacing to see which improves outcomes for people with heart failure. It may help those who need pacing to better coordinate heartbeats and relieve symptoms.
TomskAges 18–80
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Common questions
- Are there clinical trials for functionality?
- Yes. Clin2 currently lists 2,564 recruiting functionality studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a functionality trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a functionality trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.