Clinical trials
Functionality clinical trials
Below are recruiting functionality clinical trials, each written for real people, not researchers. We’re tracking 2,577 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT05150106Recruiting
Study brain and voice patterns in laryngeal dystonia
This study looks at how the brain and voice system work in people with laryngeal dystonia or voice tremor, and compares them with healthy volunteers. The goal is to better describe different “types” (phenotypes) so future care can be more targeted.
Boston, MassachusettsAges 18–80 - NCT05154253RecruitingPhase 1
Improving ankle push-off in children with cerebral palsy
This early (Phase 1) study tests a way to improve how well the ankle muscles help you push off when walking in cerebral palsy. If the ankle function improves, it may lead to a more comfortable and safer walking pattern.
Minneapolis, MinnesotaAges 8–21 - NCT05157282Recruiting
Spinal cord stimulation to improve hand function after tetraplegia
This trial tests whether a special device that stimulates the spinal cord can help people with long-lasting neck spinal cord injuries recover useful hand movement and grip strength. It may help your nervous system communicate better so daily hand tasks become easier.
Chicago, IllinoisAges 18–70 - NCT05165095Recruiting
Remote monitoring checks for new pacemakers
This trial tests how well remote monitoring features in certain pacemakers work after implantation. It may help your care team spot issues earlier and improve the remote alert system.
KremsAges 18 years+ - NCT05166954Recruiting
Bariatric surgery and heart function in people with high blood pressure
This study looks at whether bariatric (weight-loss) surgery improves heart function in people who have high blood pressure. You may be able to join if you’re already a bariatric surgery patient at the study hospital and meet the health and medication criteria.
Beijing, Beijing MunicipalityAges 17–70 - NCT05167786Recruiting
Electrical spinal cord stimulation for walking after stroke
This trial studies whether a non-surgical electrical treatment to the spinal area can improve walking and leg control after a stroke. It’s for people who have had a single stroke and still need hands-on support to walk.
Chicago, IllinoisAges 18 years+ - NCT05173740RecruitingPhase 4
Rehab program for people after an out-of-hospital cardiac arrest
This trial studies a rehabilitation program for adults who survived a first out-of-hospital cardiac arrest. It may help improve recovery after leaving the hospital by using guided follow-up and surveys to see how people are doing over time.
CopenhagenAges 18–65 - NCT05178914Recruiting
Testing heart pain treatment guided by blood-flow measurements
This study looks at how to personalize treatment for people with angina (chest pain) by measuring how well blood flows through the heart’s small vessels and the main arteries during a procedure. It may help doctors choose the right approach after your coronary angiography (heart artery imaging).
La TroncheAges 18 years+ - NCT05192655Recruiting
AI PET imaging to guide treatment for head and neck cancer
This study uses an AI computer method to analyze FDG PET scan images to help tailor (individualize) treatment for people with head and neck squamous cell carcinoma. It aims to improve how doctors plan curative treatment based on your scan.
BerlinAges 18 years+ - NCT05194098Recruiting
EEG and brain stimulation study for depression reward symptoms
This study uses non-invasive brain stimulation (like TMS) and EEG brain recordings to measure how the brain’s “reward” system works in people with major depression. It may help researchers understand which stimulation approaches best affect depression-related reward processing.
San Francisco, CaliforniaAges 18–65 - NCT05212129Recruiting
Stimulation of the ear nerve to help gut symptoms
This study tests whether stimulating a nerve in the ear (called auricular vagal nerve stimulation) can improve upper gut symptoms in teens who may have hypermobile Ehlers-Danlos syndrome (hEDS) or hypermobile spectrum disorder (HSD). It also checks whether this treatment helps nerves that control the body (autonomic nervous system) and how well the gut moves.
Milwaukee, WisconsinAges 10–18 - NCT05226247Recruiting
Check whether careful weaning prevents lung fluid buildup
This study looks at people on a breathing machine for more than 48 hours who are starting a “spontaneous breathing trial,” a test used to see if they can breathe on their own. It focuses on those at higher risk of “weaning-induced pulmonary edema,” meaning fluid can collect in the lungs during the weaning process.
DijonAges 18 years+ - NCT05228262Recruiting
Testing blood-vessel function and muscle strength in osteoporosis
This study looks at how well your blood vessels work and how strong your muscles are, in women after menopause with osteoporosis. You may be asked to start standard osteoporosis treatment, and the researchers will study pain and changes related to vascular function and sarcopenia (loss of muscle and strength).
Clermont-FerrandAges 50 years+ - NCT05231655Recruiting
Study testing fresh tumor tissue from cancer surgery or biopsy
This study collects fresh samples of tumor tissue during procedures like surgery, biopsy, or TURBT to test a cancer therapy outside the body. It may help researchers learn which treatments work better for different solid cancers.
Sheffield, South YorkshireAges 16 years+ - NCT05237687RecruitingPhase 2
Sirolimus to help prevent loss of daily function
This Phase 2 trial studies whether sirolimus can slow or prevent functional decline (more difficulty with daily activities) in older adults. You may be considered if you’re in the right age range and have no major heart, lung, liver, kidney, or recent bleeding/clotting problems.
Dallas, TexasAges 65–80 - NCT05240924Recruiting
Exposure therapy program for veterans with OCD and PTSD
This study tests whether a structured therapy approach called Exposure and Response Prevention (ERP) can improve functioning in veterans with OCD, with or without PTSD. You may be eligible if you’re receiving care through certain VA clinics or telehealth hubs and are willing to take part in ERP.
East Orange, New JerseyAges 18 years+ - NCT05254431Recruiting
Exercise timing program for breathing trouble and sleep apnea
This trial tests whether doing exercise at set intervals can improve daily function in Veterans who have both COPD (lung disease) and OSA (sleep apnea). It may help you move and function better while managing symptoms from both conditions.
Salem, VirginiaAges Any age - NCT05264675Recruiting
Treatment study for thumb tendon injury after wrist fracture
This study looks at outcomes after an EPL tendon rupture that happens with a distal radius (wrist) fracture. It may help improve how thumb function is treated and measured after this specific type of injury.
MölndalAges 16 years+ - NCT05281887Recruiting
Study of eye changes after ischemic stroke
This trial looks at how changes in the retina (the light-sensing tissue in the back of the eye) track with vision and eye function after an ischemic stroke. The goal is to understand which eye changes are linked to the stroke, which could help doctors monitor recovery.
Guangzhou, GuangdongAges 18 years+ - NCT05284006Recruiting
Non-invasive tests for Morquio A
This trial studies Morquio A (MPS IVA) using non-invasive ways to measure how the body is working, and to better understand why the condition happens. If you have Morquio A, this may help researchers learn more and improve care.
Wilmington, DelawareAges Any age - NCT05290610Recruiting
Brain stimulation mapping during epilepsy surgery planning
This study uses a special kind of brain recording with stimulation to better map seizure activity while you are already having monitoring for epilepsy surgery. It may help doctors understand how to plan safer, more effective treatment.
Minneapolis, MinnesotaAges 18 years+ - NCT05307367Recruiting
Study exercise and body muscle changes in advanced lung cancer
This study looks at why cancer can cause loss of muscle in people with advanced non–small cell lung cancer, and whether exercise can improve or explain those muscle changes. You may be asked to do physical testing and answer questionnaires while receiving standard palliative cancer treatment.
Copenhagen, DKAges 18–100 - NCT05310578Recruiting
Rehab after neck nerve surgery for persistent arm pain
This trial studies recovery and function after surgery to relieve a pinched nerve in the neck (posterior cervical decompression). It may help people with ongoing arm pain learn which rehab approach improves daily function.
JönköpingAges 18–75 - NCT05312255Recruiting
Non-drug help to improve quality of life in myeloma
This study tests non-chemotherapy supports meant to improve quality of life and immune health for people with multiple myeloma (or related conditions). Depending on the group, it may involve activities, nutrition, and/or a medication like a beta blocker.
Buffalo, New YorkAges 18 years+
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Common questions
- Are there clinical trials for functionality?
- Yes. Clin2 currently lists 2,577 recruiting functionality studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a functionality trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a functionality trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.