Clinical trials
Functionality clinical trials
Below are recruiting functionality clinical trials, each written for real people, not researchers. We’re tracking 2,577 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT05313620RecruitingPhase 4
Tofacitinib effect on clotting tests in ulcerative colitis
This study looks at how tofacitinib (and related medicines) may affect clotting and blood-platelet function, and whether this could relate to blood clot risk. It includes detailed blood and stool/colonoscopy-related testing in adults with ulcerative colitis and in some people without it.
Madrid, MadridAges 18 years+ - NCT05322824Recruiting
Study for adults with narrowed brain or neck arteries
This study enrolls people age 40 or older who have at least 50% narrowing in one brain or neck (carotid) artery. It collects clinical information to better understand this condition and how patients are doing over time.
Hangzhou, ZhejiangAges 40 years+ - NCT05324475Recruiting
Nutritional supplement to support immunity and energy in older adults
This trial tests whether a safe nutrition supplement can help older adults with malnutrition maintain immune function and energy (mitochondrial function). It may support recovery during rehabilitation, but you must meet specific nutrition and health criteria.
Lausanne, SwitzerlandAges 75 years+ - NCT05325424Recruiting
Laparoscopic spleen surgery for people with cirrhosis
This study looks at whether removing the spleen using keyhole surgery can improve “liver reserve function” in people with cirrhosis. It may be considered for patients who have an enlarged spleen and very low platelets, but it also has several safety exclusions.
Yangzhou, JiangsuAges 18 years+ - NCT05325437Recruiting
Laparoscopic spleen surgery to protect liver function in cirrhosis
This trial looks at whether a minimally invasive spleen surgery (with a specific vein-disconnection procedure) can better protect liver function in people with cirrhosis who have had variceal bleeding. It may help reduce stress on the liver after treatment, but you must meet several safety criteria.
Yangzhou, JiangsuAges 18 years+ - NCT05331521RecruitingPhase 3
Study to improve brain function in newly diagnosed glioma patients
This Phase 3 study tests a treatment plan after surgery to improve brain function and quality of life in adults with newly diagnosed, specific types of brain tumors (gliomas). It may help you keep thinking clearly and living better while your tumor is treated with standard medicines.
Heidelberg, Baden-WurttembergAges 18 years+ - NCT05333328RecruitingPhase 4
Test of ovarian function suppression for low-risk premenopausal node+ breast cancer
This trial studies whether ovarian function suppression (a treatment that lowers hormone production from the ovaries) helps women with hormone-receptor positive, HER2-negative breast cancer that has spread to lymph nodes, but who have a low-risk result on a genomic test. It may help reduce breast cancer recurrence while avoiding more intensive treatment for those who are lower risk.
Seoul, KoreaAges 20–50 - NCT05336760Recruiting
ALS study of swallowing comfort, quality of life, and PEG views
This study looks at swallowing problems in people with ALS and how they affect quality of life, including people’s attitudes toward PEG (a feeding tube). It may help researchers understand what support and information could improve comfort and day-to-day living.
LjubljanaAges 18 years+ - NCT05338294Recruiting
Tested surgery to help immune function in cirrhosis
This study looks at whether a type of keyhole spleen surgery plus cutting a large vein can improve immune function in people with cirrhosis. It may help reduce immune problems that can happen after complications like bleeding from varices (enlarged veins in the esophagus/stomach).
Yangzhou, JiangsuAges 18 years+ - NCT05342454Recruiting
Brain tumor surgery patients using brain scan and mapping software
This study checks a new computer software tool that helps doctors map important brain networks and how blood flow responds during brain scans. It may help improve planning and safety for people having brain tumor surgery.
Houston, TexasAges 18 years+ - NCT05343130Recruiting
Brain-controlled electrical therapy for arm mobility after spinal injury
This trial studies a brain-computer system that helps control electrical stimulation to improve arm movement after a spinal cord injury. It may help with functional use of the upper limbs during rehabilitation if you meet the specific injury, spasticity, and safety requirements.
Tlalpan, Mexico CityAges 18 years+ - NCT05345015Recruiting
Radio waves for muscle or low back pain and function
This trial tests whether a high-frequency radio-wave treatment can reduce pain and improve movement in adults with a muscle strain (hamstring) or acute or chronic low back pain. It may help you feel less pain and function better, depending on your specific injury and medical details.
KavalaAges 18–65 - NCT05352958Recruiting
Ultrasound checks breathing muscle function in ALS
This study uses a quick ultrasound test to check how well the breathing muscle (the diaphragm) works in people with amyotrophic lateral sclerosis (ALS). It may help doctors monitor breathing changes over time and guide care.
DijonAges 18 years+ - NCT05359263RecruitingPhase 2
Dapagliflozin for kidney disease to improve heart structure
This Phase 2 study tests whether dapagliflozin can improve heart structure and function in people with chronic kidney disease (CKD). Dapagliflozin is a kidney-heart medicine that may affect how the heart changes over time, measured by heart scans.
CopenhagenAges 18 years+ - NCT05369520Recruiting
Noninvasive spinal stimulation to improve bladder and autonomic function
This trial tests a noninvasive way to stimulate the spinal cord to help the body’s “automatic functions” (like bladder, bowel, and sexual function) after spinal cord injury. If you’ve had a stable, complete spinal cord injury for more than a year, you may be eligible to try this approach and help researchers evaluate recovery.
Vancouver, British ColumbiaAges 19–60 - NCT05376254Recruiting
3D heart scan study during LVAD implantation
This study uses special 3D heart imaging to better measure right-heart function during LVAD surgery. It may help doctors understand how the right side of the heart responds when a mechanical pump is put in.
Edmonton, AlbertaAges 16 years+ - NCT05386615Recruiting
Pregnancy follow-up registry after Exablate for fibroids
This study keeps track of people’s pregnancy and birth outcomes after having Exablate treatment for symptomatic uterine fibroids. It may help doctors understand how safe and effective the treatment can be for future pregnancy plans.
Los Angeles, CaliforniaAges 18–50 - NCT05394987Recruiting
Testing new glasses and vision function in amblyopia adults
This study looks at how changing your glasses prescription affects vision and visual function in adults with amblyopia (often called “lazy eye”). It may help researchers understand which optical correction best supports clearer, more balanced vision.
Waterloo, OntarioAges 18–39 - NCT05396352Recruiting
Study brain-task skills in autism using brain stimulation
This study looks at how different brain regions work in people with autism and in neurotypical adults using thinking tasks, MRI scans, and a noninvasive brain stimulation called tDCS. It may help researchers better understand social and executive thinking—how you plan and manage tasks.
Washington D.C., District of ColumbiaAges 18–35 - NCT05400499Recruiting
Deep brain stimulation study in Parkinson’s visuomotor function
This trial studies how deep brain stimulation affects hand-eye (visuomotor) coordination in people with Parkinson’s. It may help researchers understand whether the stimulation settings change movement control for daily tasks.
Cleveland, OhioAges Any age - NCT05402488Recruiting
Studying sleep recovery in adults with neurodegeneration
This study looks at how sleep “recovery” works in people with neurodegenerative diseases (conditions where abnormal proteins build up). It uses sleep recordings and sounds during sleep to see how sleep patterns relate to outcomes.
Zurich, Canton of ZurichAges 18 years+ - NCT05413616Recruiting
Personalized nutrition and activity therapy for older hospital patients
This study tests whether a tailored nutrition plan plus a step-by-step exercise program can improve physical strength and performance in older adults in the hospital. It compares these interventions to the usual hospital care you would normally get.
Nijmegen, GelderlandAges 65 years+ - NCT05414357Recruiting
Sleep problems study in breast cancer and effects on thinking
This study looks at how sleep problems affect thinking and daily quality of life in people treated for early breast cancer. It may help researchers understand which sleep issues to target to improve well-being during or after treatment.
CaenAges 45–65 - NCT05421325RecruitingPhase 2
Vaccine-like immune treatment to prevent lung infections in seniors
This Phase 2 study tests a site-specific immune “booster” in people age 65 and older to help improve natural immunity and reduce respiratory (lung/airway) infections. You may be eligible if you can consent, are in an eligible living situation, and are not currently using certain immune-suppressing medicines.
Burnaby, British ColumbiaAges 65 years+
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Common questions
- Are there clinical trials for functionality?
- Yes. Clin2 currently lists 2,577 recruiting functionality studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a functionality trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a functionality trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.