Clinical trials
Gastric Cancer or Gastroesophageal Junction Adenocarcinoma clinical trials
Below are recruiting gastric cancer or gastroesophageal junction adenocarcinoma clinical trials, each written for real people, not researchers. We’re tracking 1,157 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT05539105Recruiting
Watching recovery after surgery for upper stomach cancer
This study keeps track of how people recover after surgery to remove the upper part of the stomach and nearby lymph nodes. It mainly helps doctors understand which surgical reconstruction methods work best and how patients do over time.
Shanghai, Shanghai MunicipalityAges 18–80 - NCT06992362RecruitingPhase 2
Pre- and post-surgery treatment for HER2+ hepatoid stomach cancer
This trial tests a treatment plan given before and after surgery for a rare type of stomach cancer called hepatoid adenocarcinoma. It's for people whose tumors have a specific HER2 protein marker and are at an early enough stage that surgery is still possible.
BeijingAges 18–75 - NCT07325630RecruitingPhase 2
Perioperative study of IBI363 for MHC-II-negative advanced stomach cancer
This trial tests a new treatment called IBI363 given before and after surgery for people with a certain type of advanced stomach cancer that lacks the MHC-II marker. The goal is to see if it helps shrink the tumor and improve outcomes.
Hangzhou, ZhejiangAges 18–75 - NCT07130903RecruitingPhase 2
Fruquintinib plus special radio waves for advanced colon cancer
This trial tests whether combining fruquintinib (a pill) with low-level radio waves can help people whose metastatic colorectal cancer has stopped responding to or is intolerant of standard treatments. It’s for those who have tried certain chemotherapies and anti-VEGF therapy.
Bay City, MichiganAges 22 years+ - NCT06427941RecruitingPhase 1
Study of BGB-B2033 drug for advanced solid tumors
This trial tests a new drug, BGB-B2033, alone or with other treatments, for people with advanced liver, stomach, lung, or germ cell cancers that have not responded to standard therapy. The goal is to see if the drug is safe and works against these tumors.
Goodyear, ArizonaAges 18 years+ - NCT06937177RecruitingPhase 2
Testing mifomelatide to help maintain weight during chemo
This trial tests an investigational drug called mifomelatide (TCMCB07) to see if it can help people with newly diagnosed colorectal or pancreatic cancer maintain a healthy weight while receiving certain types of chemotherapy. You would give yourself a daily injection under the skin.
Tucson, ArizonaAges 18 years+ - NCT03259867RecruitingPhase 2
TACE plus immune therapy for liver or stomach cancer
This trial tests a combination treatment using a targeted liver procedure plus an immune “checkpoint” medicine to slow cancer growth. It may help people with advanced liver cancer (HCC) or metastatic stomach cancer when standard treatments have not worked.
Orange, CaliforniaAges 18–80 - NCT04214119Recruiting
Capsule test during endoscopy to find early esophageal cancer
This trial studies an “EsophaCap” capsule that can be swallowed during an endoscopy to help detect early esophageal cancer. It may help find cancer earlier and guide next steps, if your results are concerning.
Baltimore, MarylandAges 18 years+ - NCT04613570Recruiting
Follow-up endoscopy plan for early stomach changes
This study looks at how often and how intensely to do follow-up stomach camera exams (endoscopy) with small biopsies for people at risk of stomach cancer. It may help personalize your follow-up schedule based on your specific stomach findings.
PortoAges 45 years+ - NCT04734821Recruiting
Fluorescent imaging during stomach or esophagus surgery
This study tests whether a special fluorescent camera during surgery can help surgeons better operate on resectable (removable) stomach or esophagus cancer. It may help improve how surgery is guided, with the goal of safer and more accurate tumor removal.
StrasbourgAges 18 years+ - NCT04949737Recruiting
Study stomach bacteria and stomach cancer in Martinique adults
This study looks at how common Helicobacter pylori (a common stomach germ) is in adults with stomach cancer in Martinique, and how it relates to stomach cancer. It mainly involves answering questionnaires and allowing study details to be collected to better understand risk and patterns.
Fort-de-FranceAges 18 years+ - NCT05188313RecruitingPhase 3
HER2 medicines before surgery for resectable esophageal cancer
This trial tests two targeted medicines, trastuzumab and pertuzumab (HER2-blocking drugs), given before surgery for HER2-positive esophageal or stomach-esophagus junction cancer. The goal is to shrink the tumor and improve how well surgery works and outcomes after treatment.
AmsterdamAges 18 years+ - NCT05319639RecruitingPhase 1/Phase 2
Irinotecan plus immunotherapy for stomach cancer
This Phase I/II trial tests how well irinotecan combined with tislelizumab (an immunotherapy) treats advanced stomach or gastroesophageal junction adenocarcinoma. It mainly looks at safety and the best way to use this combination, and may help shrink tumors or slow disease growth.
Fuzhou, FujianAges 18–75 - NCT05323929Recruiting
Checks how scar depth after stomach tumor removal affects healing
This study looks at early stomach cancer treated with ESD, a procedure to remove the tumor through the stomach lining, and how the depth of the scar relates to healing. It may help doctors predict better outcomes and improve the procedure for suitable patients.
Hangzhou, ZhejiangAges 18–75 - NCT05332002RecruitingPhase 2
Study chemotherapy plus immunotherapy for HER2-negative esophageal cancer
This Phase 2 trial tests a combination treatment called sFOLFOXIRI for advanced esophageal or stomach-area cancer that is HER2-negative. It aims to see how well the treatment works and whether it is safe for people who have not had standard chemotherapy for this metastatic cancer yet.
Hamilton, New JerseyAges 18 years+ - NCT05347524Recruiting
Blood test study to detect stomach cancer spread in the belly
This study checks whether a blood liquid biopsy test can detect when stomach cancer has spread to the lining of the abdomen (peritoneal metastasis). It compares people with confirmed belly spread to people whose belly lining tests were negative, using blood samples before/around treatment decisions.
Shanghai, Shanghai MunicipalityAges 18–74 - NCT05427383RecruitingPhase 2/Phase 3
KN026 plus chemo for HER2-positive stomach cancer after first treatment failure
This trial tests KN026 together with chemotherapy in people with HER2-positive advanced stomach (or gastro-esophageal junction) cancer that has already grown despite first-line treatment with trastuzumab plus chemotherapy. It may help by targeting HER2 while also using chemotherapy to control the cancer.
BeijingAges 18 years+ - NCT05593458RecruitingPhase 3
Stomach cancer surgery before chemo: artery-based or drip chemo
This trial compares two ways of giving chemotherapy before surgery for locally advanced stomach or stomach–esophagus cancer: chemo sent through an artery versus chemo given through an IV line. It also studies adding PD-1 immunotherapy to see which approach works better and is safer.
Hangzhou, ZhejiangAges 18–75 - NCT05768932RecruitingPhase 1
Study drug for advanced cancers or relapsed AML
This Phase 1 trial tests BAL0891, a new study treatment, in people with advanced solid tumors that have run out of treatment options, or in relapsed/refractory acute myeloid leukemia (AML). The goal is to find a safe dose and see how well it may work in these hard-to-treat cancers.
New Haven, ConnecticutAges 18 years+ - NCT05930860Recruiting
Endoscopic treatment for certain superficial stomach growths
This trial studies how safe and effective a procedure called endoscopic submucosal dissection (ESD) is for treating certain early, superficial stomach (gastric) growths. It may be an option if your growth fits the endoscopy criteria and you are not a good candidate for stomach surgery.
RomeAges 18 years+ - NCT05956847Recruiting
Studying DNA fragments in stomach cancer tissue
This trial looks at tiny pieces of DNA found outside cells in stomach tissue to better understand how gastric (stomach) cancer starts and progresses. It may help future patients by improving how doctors study stomach cancer from biopsy and surgical samples.
Xi'an, ShaanxiAges 18–80 - NCT06040801Recruiting
Geriatric care for older adults with advanced stomach, bile duct, or pancreatic cancer
This study tests a special geriatric (older-adult) care program for people over 65 with advanced stomach, bile duct, or pancreatic cancer who are receiving palliative chemotherapy. The goal is to see if extra support from a geriatric team can help improve quality of life and treatment outcomes.
Taoyuan, TaiwanAges 65 years+ - NCT06055439RecruitingPhase 1/Phase 2
CAR T cell therapy for GI cancers
This trial tests a new type of immunotherapy called CAR T cells that target a protein (CDH17) found on certain stomach, colon, and rectal cancers. It's designed for people whose cancer has spread and has been treated before.
Atlanta, GeorgiaAges 18–85 - NCT06071507Recruiting
Comparing treatments for stomach blockage in pancreatic cancer
This trial compares three ways to relieve a stomach or duodenal blockage caused by pancreatic cancer: placing a stent, performing a bypass with a thin tube (endoscopy), or surgical bypass. It aims to find which option helps patients eat and feel better sooner.
ParisAges 18 years+
Hear when a new Gastric Cancer or Gastroesophageal Junction Adenocarcinoma trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.
Common questions
- Are there clinical trials for gastric cancer or gastroesophageal junction adenocarcinoma?
- Yes. Clin2 currently lists 1,157 recruiting gastric cancer or gastroesophageal junction adenocarcinoma studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a gastric cancer or gastroesophageal junction adenocarcinoma trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a gastric cancer or gastroesophageal junction adenocarcinoma trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
- Gastric Cancer, Gastroesophageal Junction Cancer
- Gastric / Gastroesophageal Junction Adenocarcinoma
- Gastric or Gastroesophageal Junction Adenocarcinoma
- AFP Gastric or Gastroesophageal Junction Adenocarcinoma
- Gastric and Gastroesophageal Junction (GEJ) Adenocarcinoma
- Gastroesophageal Junction Adenocarcinoma
- Gastroesophageal-junction Cancer
- Metastatic Gastroesophageal Junction Adenocarcinoma
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.