Clinical trials
Gastric or Esophagogastric Junction Adenocarcinoma clinical trials
Below are recruiting gastric or esophagogastric junction adenocarcinoma clinical trials, each written for real people, not researchers. We’re tracking 936 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT03825861RecruitingPhase 2
Before-surgery chemotherapy for locally advanced stomach cancer
This Phase 2 study tests chemotherapy given before surgery (called FOLFIRINOX) for people with locally advanced stomach cancer. The goal is to shrink the tumor and improve outcomes after the surgery plan is completed.
São PauloAges 18–75 - NCT03941561RecruitingPhase 3
Shorter versus longer chemotherapy for stage II stomach cancer
This trial compares two lengths of an oral chemotherapy medicine (9 months vs 1 year) after surgery for stage II stomach cancer. It aims to see which schedule works better and is easier to complete, while checking safety for people without major health problems.
AnqingAges 18–75 - NCT03961945Recruiting
Testing a new way to diagnose Barrett’s esophagus
This study tests minimally invasive, sample-based tests during an endoscopy to find Barrett’s esophagus and help sort it from esophageal cancer risk. It may help doctors spot changes earlier and more accurately using less invasive methods than standard tissue testing alone.
Scottsdale, ArizonaAges 18–90 - NCT04097067Recruiting
Radiation therapy for slow-growing stomach lymphoma
This study tests whether a specific course of focused radiation (20 Gy) can control indolent (slow-growing) lymphoma in the stomach or upper small intestine. It may help shrink or stabilize tumors and lymph node involvement while limiting side effects.
Münster, North Rhine-WestphaliaAges 18 years+ - NCT04107077RecruitingPhase 2
HIPEC surgery plus chemotherapy for advanced stomach cancer
This study tests whether a specialized surgery called HIPEC (heat-treated chemotherapy placed in the belly) can improve outcomes for people with advanced stomach cancer that has reached the lining of the abdomen. It’s given after you’ve already had standard chemotherapy, aiming to better control disease in the belly.
Chicago, IllinoisAges 18 years+ - NCT04278222RecruitingPhase 2
Anlotinib plus immunotherapy for advanced stomach cancer
This Phase 2 study tests whether combining two medicines—anlotinib and toripalimab—can work well as first treatment for advanced (stage IV) stomach cancer. It’s meant for people who have an adequate overall health status and certain blood/organ function levels.
ShanghaiAges 18 years+ - NCT04379596RecruitingPhase 2
Testing T-DXd combinations for HER2 stomach or esophagus cancer
This Phase 2 study tests how safe and effective T-DXd (an anti-cancer medicine) is in combination for people with advanced stomach/GEJ/esophagus cancer that is HER2-positive or HER2-low. It may help people whose cancer has spread or cannot be removed, depending on their prior treatments and test results.
Santa Monica, CaliforniaAges 18–130 - NCT04483076RecruitingPhase 3
Chemo before stomach surgery with different cycles
This trial studies whether giving oxaliplatin plus S-1 (SOX) chemotherapy before stomach surgery works best when given for different cycle lengths. It may help shrink stage III gastric cancer before a standard D2 gastrectomy and improve outcomes.
Beijing, Beijing MunicipalityAges 18–70 - NCT04547725Recruiting
Surgery plus chemotherapy for stomach cancer in the belly lining
This study tests whether a thorough surgery to remove stomach cancer in the abdomen, followed by chemotherapy given through the belly and by vein, can improve outcomes. It’s for people newly diagnosed with stomach cancer that has limited spread to the belly lining.
TaipeiAges 20–75 - NCT04557969Recruiting
Surgery and tumor testing in gastrointestinal stromal tumors (GIST)
This study looks at how surgery for gastrointestinal stromal tumors (GIST) works, and collects tumor samples to study them under the microscope and by DNA testing. Your results may help researchers better predict tumor behavior and guide future treatment.
Bethesda, MarylandAges 6 years+ - NCT04595929Recruiting
Tested aerosol chemotherapy inside the abdomen for stomach cancer
This trial looks at a way to give chemotherapy into the abdomen (through a small tube during laparoscopy) for certain stomach cancers. It aims to see whether this approach improves cancer control and surgical outcomes for people whose tumors can potentially be removed.
Saint PetersburgAges 18–65 - NCT04597294RecruitingPhase 3
Preventive pre-op HIPEC for advanced stomach cancer
This Phase 3 trial studies whether adding a heated chemotherapy procedure during surgery (HIPEC) before the main cancer treatment can lower the chance that stomach cancer returns in the belly. It is for people with advanced stomach cancer who are at higher risk of cancer coming back in the peritoneum (the lining of the abdomen).
Krakow, Lesser Poland VoivodshipAges 18–75 - NCT04613570Recruiting
Follow-up endoscopy plan for early stomach changes
This study looks at how often and how intensely to do follow-up stomach camera exams (endoscopy) with small biopsies for people at risk of stomach cancer. It may help personalize your follow-up schedule based on your specific stomach findings.
PortoAges 45 years+ - NCT04740346Recruiting
Study survival and quality of life by follow-up time after stomach surgery
This study looks at how long people with stage II or III stomach (gastric) cancer tend to live and how their day-to-day well-being changes over different follow-up times after surgery. It may help doctors understand the best follow-up schedule to support recovery.
Goyang-si, Gyeonggi-doAges 19 years+ - NCT04787354RecruitingPhase 3
Choosing the best length of oxaliplatin after stomach surgery
This trial tests whether giving oxaliplatin for a shorter or longer time works best after curative surgery for stage II–III stomach (or stomach–esophagus junction) cancer. It aims to improve outcomes while balancing side effects from chemotherapy.
Gyeonggi-doAges 19 years+ - NCT04789486RecruitingPhase 1/Phase 2
MR-guided radiation plus nanoparticles for central lung or pancreatic tumors
This early-phase study tests a new way to deliver focused radiation using MRI guidance and tiny particles, aiming to treat certain central lung tumors or locally advanced pancreatic cancer. It’s designed to see how safe it is and how well it can control these tumors.
Boston, MassachusettsAges 18 years+ - NCT04840056Recruiting
Testing ways to predict stomach cancer risk
This trial looks at adults with stomach lining changes—either atrophic gastritis or intestinal metaplasia—and studies how to predict who may be at risk for stomach cancer. It may help earlier identification and closer monitoring for people with these conditions.
Shatin, New TerritoriesAges 18 years+ - NCT04842916Recruiting
Study blood, tumor tissue, and preferences to predict stomach cancer response
This study looks at stomach (or stomach–esophagus junction) cancer tissue, treatment details, and patient-reported experiences to better predict how you may respond to standard chemotherapy. It may help personalize future treatment by identifying markers that connect your tumor environment and your expected outcomes.
BrestAges 18–85 - NCT04843215Recruiting
Surgery comparison for advanced stomach cancer after initial surgery
This trial studies whether removing all of the fatty lining (omentum) or only part of it during surgery leads to better outcomes in people with advanced stomach cancer. It also checks that participants can safely have the same stomach-cancer chemotherapy plan after surgery.
Tianjin, Tianjin MunicipalityAges 18–70 - NCT04943484Recruiting
ICG camera dye test during surgery for advanced stomach cancer
This trial tests whether an “ICG” dye and special camera can help surgeons see cancer more clearly during surgery for advanced stomach cancer. It may help improve how safely and accurately surgeons remove the tumor and nearby lymph nodes.
Milan, ItaliaAges 18 years+ - NCT04949737Recruiting
Study stomach bacteria and stomach cancer in Martinique adults
This study looks at how common Helicobacter pylori (a common stomach germ) is in adults with stomach cancer in Martinique, and how it relates to stomach cancer. It mainly involves answering questionnaires and allowing study details to be collected to better understand risk and patterns.
Fort-de-FranceAges 18 years+ - NCT05010863Recruiting
Test and develop a stomach cancer detection kit
This study looks for marker signals from stomach cancer tissue to improve a detection kit. You may be asked to provide tissue samples, especially if you have a new stomach cancer diagnosis and have not had anti-cancer treatment yet.
Wenzhou, ZhejiangAges Any age - NCT05140746Recruiting
Predicting how well chemotherapy works before stomach surgery
This study looks for ways to predict whether neoadjuvant chemotherapy (chemo given before surgery) will work well in people with locally advanced stomach cancer. It may help doctors choose the best treatment plan sooner based on your test results.
Shanghai, Shanghai MunicipalityAges 18–75 - NCT05229432Recruiting
Oatmeal meal test to study stomach movement in eosinophilic gastritis
This study looks at how your stomach moves (gastric motility) in people with eosinophilic gastritis, using a special oatmeal meal. The goal is to better understand stomach function and how it may relate to symptoms.
Chicago, IllinoisAges 18–59
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Common questions
- Are there clinical trials for gastric or esophagogastric junction adenocarcinoma?
- Yes. Clin2 currently lists 936 recruiting gastric or esophagogastric junction adenocarcinoma studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a gastric or esophagogastric junction adenocarcinoma trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a gastric or esophagogastric junction adenocarcinoma trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
- Gastric / Gastroesophageal Junction Adenocarcinoma
- Adenocarcinoma of Esophagogastric Junction
- Gastric or Gastroesophageal Junction Adenocarcinoma
- AFP Gastric or Gastroesophageal Junction Adenocarcinoma
- Gastric Cancer or Gastroesophageal Junction Adenocarcinoma
- Gastric and Gastroesophageal Junction (GEJ) Adenocarcinoma
- Siewert Type II Adenocarcinoma of Esophagogastric Junction
- Gastric Adenocarcinoma
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.