Clinical trials
Gastric or Esophagogastric Junction Adenocarcinoma clinical trials
Below are recruiting gastric or esophagogastric junction adenocarcinoma clinical trials, each written for real people, not researchers. We’re tracking 936 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT05291728Recruiting
Screening for early stomach cancer in Shaanxi
This trial is a community screening program to look for early stomach cancer in adults in Shaanxi. It may help doctors find cancer earlier, when treatment can be more effective.
Xi'an, ShaanxiAges 20 years+ - NCT05323929Recruiting
Checks how scar depth after stomach tumor removal affects healing
This study looks at early stomach cancer treated with ESD, a procedure to remove the tumor through the stomach lining, and how the depth of the scar relates to healing. It may help doctors predict better outcomes and improve the procedure for suitable patients.
Hangzhou, ZhejiangAges 18–75 - NCT05344339Recruiting
Compare two stomach reconstruction methods after stomach cancer surgery
This study compares two surgical reconstruction techniques after a distal gastrectomy (removing the lower part of the stomach) for gastric (stomach) cancer. It may help find which method leads to better recovery and outcomes after surgery.
Ho Chi Minh CityAges 18–80 - NCT05483491RecruitingPhase 1
TCR cell therapy for select metastatic cancers
This Phase 1 trial tests a personalized immune-cell treatment (TCR-T cells) for certain metastatic cancers. It targets cancers that carry a specific marker and requires patients to have a specific immune-system match, aiming to improve cancer control when standard options were already tried.
New Brunswick, New JerseyAges 18 years+ - NCT05494086Recruiting
Laparoscopic stomach surgery for early gastric cancer
This study looks at a surgical technique (“dual-port laparoscopic distal gastrectomy”) for people with stomach adenocarcinoma at an early, specific stage. The goal is to remove the tumor with clean margins (called an “R0” result) and see how this approach works safely.
Guangzhou, GuangdongAges 18–75 - NCT05495139Recruiting
Gastric bypass stent study for fatty liver disease
This small study tests whether placing a gastric bypass stent can improve nonalcoholic fatty liver disease (fatty liver not caused by heavy alcohol). You may be considered if your liver fat is high on a special MRI scan and you meet several safety and medical history rules.
ShanghaiAges 18–65 - NCT05526105Recruiting
Ultrasound for stomach fluid in ICU patients
This trial tests using an ultrasound scan to estimate stomach fluid and volume in ICU patients. It may help clinicians better assess aspiration risk and prepare for safe anesthesia or procedures.
Lebanon, New HampshireAges 18–100 - NCT05536102RecruitingPhase 2
Surgery-plus chemo and immunotherapy for HER2-negative gastric cancer
This Phase 2 trial studies whether adding two medicines (XELOX and tislelizumab) and another chemotherapy drug (PLD) around the time of surgery works better and is safe for people with stage III gastric (stomach) cancer. It is designed for tumors that are HER2-negative and PD-1/L1 positive.
ShanghaiAges 18–75 - NCT05537129Recruiting
Laparoscopic vs open stomach surgery for stomach cancer
This trial compares two ways surgeons remove the entire stomach (total gastrectomy): laparoscopic (small keyhole cuts) versus open surgery (one larger cut). It’s testing which approach is safer and works better for people with certain stages of stomach cancer.
Shanghai, Shanghai MunicipalityAges 20–80 - NCT05561907Recruiting
Endoscopic vs. surgical bypass for stomach blockage from cancer
This trial compares two ways to bypass a blockage in your stomach caused by cancer near the pancreas or duodenum. Both approaches create a new connection so food can pass through, but one uses a camera-guided tube (endoscopic) and the other is surgical. The study will see which works better for your symptoms and quality of life.
New Brunswick, New JerseyAges 18 years+ - NCT05593458RecruitingPhase 3
Stomach cancer surgery before chemo: artery-based or drip chemo
This trial compares two ways of giving chemotherapy before surgery for locally advanced stomach or stomach–esophagus cancer: chemo sent through an artery versus chemo given through an IV line. It also studies adding PD-1 immunotherapy to see which approach works better and is safer.
Hangzhou, ZhejiangAges 18–75 - NCT05618821RecruitingPhase 2
Indocyanine green dye during stomach surgery for leftover cancer
This Phase 2 study tests whether using a special light-activated dye (indocyanine green) during laparoscopic stomach surgery can improve surgical outcomes for people with remnant (leftover) stomach cancer that has not spread to distant organs. It may help surgeons better find lymph nodes while operating.
Fuzhou, FujianAges 18–75 - NCT05698992Recruiting
Rehab program after surgery for esophageal or stomach cancer
This trial tests a rehabilitation and recovery program for people with esophageal or stomach cancer who are planning curative surgery at Skåne University Hospital. It may help you regain strength and function after treatment, using a structured recovery approach.
Lund, LundAges 18 years+ - NCT05722275Recruiting
Predicting peritoneal spread in advanced stomach cancer
This trial uses CT scan images and a look inside the abdomen (laparoscopy) to predict whether advanced stomach cancer has spread to the lining of the abdomen (the peritoneum). It may help your care team better identify who already has peritoneal spread and who might not.
BeijingAges 18 years+ - NCT05930860Recruiting
Endoscopic treatment for certain superficial stomach growths
This trial studies how safe and effective a procedure called endoscopic submucosal dissection (ESD) is for treating certain early, superficial stomach (gastric) growths. It may be an option if your growth fits the endoscopy criteria and you are not a good candidate for stomach surgery.
RomeAges 18 years+ - NCT05956847Recruiting
Studying DNA fragments in stomach cancer tissue
This trial looks at tiny pieces of DNA found outside cells in stomach tissue to better understand how gastric (stomach) cancer starts and progresses. It may help future patients by improving how doctors study stomach cancer from biopsy and surgical samples.
Xi'an, ShaanxiAges 18–80 - NCT05975749RecruitingPhase 2
Trastuzumab, serplulimab, and chemo after stomach cancer surgery
This Phase 2 study looks at whether adding serplulimab to trastuzumab and chemotherapy after surgery can lower the chance of stomach cancer coming back. It is for people with HER2-positive stage II–III stomach adenocarcinoma who have already had curative surgery with lymph node removal.
Shanghai, Shanghai MunicipalityAges 20–80 - NCT05991947Recruiting
Blood test for early stomach cancer detection
This study is testing a new way to find stomach (gastric) cancer early using a simple blood test. It may help people who have just been diagnosed with stage I, II, or III stomach cancer and have not started treatment yet.
Hangzhou, ZhejiangAges 18–100 - NCT06008054RecruitingPhase 2
New drug combo for advanced gastrointestinal cancers
This trial tests two new drugs (BL-B01D1 and SI-B003) alone or with a standard immunotherapy for advanced gastrointestinal cancers. The goal is to see if these combinations shrink tumors and are safe.
Beijing, Beijing MunicipalityAges 18–75 - NCT06008925RecruitingPhase 1/Phase 2
VG161 plus nivolumab for advanced gastric cancer
This trial tests a new combination therapy (VG161, a herpes-based virus therapy, plus nivolumab) for people with advanced stomach or gastroesophageal junction cancer that has not responded to at least two previous treatments, including a PD-1 inhibitor. The goal is to see if this combination can shrink tumors or slow cancer growth.
Beijing, Beijing MunicipalityAges 18–75 - NCT06027242Recruiting
Glutamine supplement after stomach cancer surgery
This trial tests if taking glutamine (a nutrient) as an oral supplement helps patients recover after surgery to remove stomach cancer. It aims to see if it improves healing and quality of life.
TaipeiAges 20 years+ - NCT06035250Recruiting
AI predicts stomach cancer response to chemo before surgery
This study tests whether an AI tool can predict how well stomach cancer responds to chemotherapy before surgery. It uses CT scans and biopsy images taken before treatment starts to see if the AI can help guide future care.
BeijingAges 18 years+ - NCT06036745RecruitingPhase 2
Palizumab and SOX chemo after gastric cancer surgery
This trial tests adding palizumab (an immunotherapy) to standard SOX chemotherapy after surgery for stage IIIB-IIIC gastric or GEJ cancer. It's for people whose tumors have certain markers (MSI-H, TMB-H, or high PD-L1) that may make immunotherapy more effective.
Shanghai, Shanghai MunicipalityAges 18–75 - NCT06055387Recruiting
Frailty care for older stomach cancer patients after surgery
This study tests a frailty assessment and intervention program for people aged 65+ with stage II or III stomach cancer who will have surgery and chemotherapy afterward. It aims to improve recovery and quality of life.
Taoyuan, TaiwanAges 65 years+
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Common questions
- Are there clinical trials for gastric or esophagogastric junction adenocarcinoma?
- Yes. Clin2 currently lists 936 recruiting gastric or esophagogastric junction adenocarcinoma studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a gastric or esophagogastric junction adenocarcinoma trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a gastric or esophagogastric junction adenocarcinoma trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
- Gastric / Gastroesophageal Junction Adenocarcinoma
- Adenocarcinoma of Esophagogastric Junction
- Gastric or Gastroesophageal Junction Adenocarcinoma
- AFP Gastric or Gastroesophageal Junction Adenocarcinoma
- Gastric Cancer or Gastroesophageal Junction Adenocarcinoma
- Gastric and Gastroesophageal Junction (GEJ) Adenocarcinoma
- Siewert Type II Adenocarcinoma of Esophagogastric Junction
- Gastric Adenocarcinoma
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.