Clinical trials
Gastrointestinal clinical trials
Below are recruiting gastrointestinal clinical trials, each written for real people, not researchers. We’re tracking 469 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07707258Recruiting
Remimazolam with oliceridine for sedation in older adults during GI endoscopy
This trial tests two medicines, remimazolam (a sedative) and oliceridine (a pain reliever), to see if they work well together for sedation during a painless gastrointestinal (GI) endoscopy in people aged 65 to 80. It aims to find a safe and effective option for older adults.
Shanghai, Shanghai MunicipalityAges 65–80 - NCT04924075RecruitingPhase 2
Belzutifan for cancers linked to VHL or HIF-2α changes
This Phase 2 study tests belzutifan (MK-6482) to treat certain advanced cancers caused by specific gene or disease changes, including VHL-related tumors and HIF-2α related tumors. It may help shrink tumors or slow their growth in people whose cancer matches these genetic or disease patterns.
Los Angeles, CaliforniaAges 12 years+ - NCT04902248Recruiting
Compare two procedures for hard-to-stop upper stomach bleeding
This trial studies whether a newer “OTSC” procedure works as well as a standard procedure called angiographic embolization to stop active, hard-to-control upper gastrointestinal bleeding. It may help people whose bleeding continues or comes back even after initial endoscopy treatment.
Beijing, Beijing MunicipalityAges 18 years+ - NCT04662918Recruiting
Test the CAGIB score to predict death in cirrhosis with bleeding
This study checks whether a score called CAGIB can accurately predict the risk of dying during the hospital stay for people with cirrhosis who have sudden bleeding in the digestive tract. It may help doctors identify who needs the most urgent care and monitor outcomes more accurately.
Scranton, PennsylvaniaAges 18 years+ - NCT04363983Recruiting
Study of immune and tumor interactions in digestive cancers
This study looks at how tumors in the digestive system interact with the body’s immune system and the surrounding environment. Results may help improve understanding of these cancers and guide future treatments.
Boulogne-BillancourtAges 18 years+ - NCT04208828Recruiting
IVIG for difficult gastrointestinal auto-immune nerve symptoms
This trial tests intravenous immunoglobulin (IVIG), a donated antibody treatment, for people whose gastrointestinal (GI) “motor” symptoms are not improving with standard care and may be auto-immune related. If you’re eligible, IVIG could help calm the immune system and improve gut movement symptoms.
Louisville, KentuckyAges 12–90 - NCT02523118Recruiting
Measuring symptoms and test results in eosinophilic gut diseases
This study looks at how eosinophilic inflammation in the esophagus and intestines affects outcomes like symptoms and test findings. It may help clinicians better understand these conditions and track what changes over time.
Phoenix, ArizonaAges 3 years+ - NCT07564466RecruitingPhase 2
SKB571 treatment for gastrointestinal tumors
This study tests a new drug called SKB571 in people with stomach, intestinal, or related cancers. The goal is to see if it can shrink tumors and help patients live longer.
Chongqing, Chongqing MunicipalityAges 18–75 - NCT01750619Recruiting
Endoscopic removal of early and cancer GI growths
This trial looks at outcomes after doctors remove abnormal or cancerous growths in the digestive tract using an endoscope (a flexible camera passed through the body). It may help improve how safely and effectively these procedures are done.
San Francisco, CaliforniaAges 18 years+ - NCT01048281Recruiting
Study of stomach and esophagus cancer samples
This study looks at stomach (gastric) and esophagus cancer, using clinical information and tissue samples. It may help researchers better understand these cancers and improve future care.
Stanford, CaliforniaAges 18 years+ - NCT07712107Recruiting
Gastrointestinal Cancer Screening Study Using Combined Detection
This study tests a new way to screen for stomach and digestive cancers using a combination of tests. It compares different screening plans to see which works best for people in their middle years.
Zhaoqing, GuangdongAges 45–74 - NCT07561840Recruiting
Exercise Training After Stomach or Esophagus Cancer Surgery
This study tests whether a guided exercise program helps people recover better after surgery for esophageal or gastric (stomach) cancer. Researchers will track your strength, fitness, and quality of life over time.
Hirakata, OsakaAges 18 years+ - NCT07779772Recruiting
Diet changes for children with eosinophilic gut disorders
This trial compares different elimination diets to see which one best reduces inflammation in children with eosinophilic gastrointestinal disorders. Your child might have fewer symptoms and a better outcome if the right diet is found.
Adana, SarıcamAges 2–18 - NCT07782203Recruiting
Tissue bank for digestive conditions and cancers
This study collects tissue samples from people with digestive conditions or cancers during routine procedures like endoscopy or surgery. The samples are used to build models for research, helping researchers better understand these diseases and develop new treatments.
StrasbourgAges 18 years+ - NCT07858110Recruiting
Wheat flour milling and blood sugar response
This study tests whether bread made from wheat milled in different ways affects blood sugar levels and stomach comfort. If you join, you will eat study breads for 14 days and wear a glucose monitor to track your body's response.
Bergen, VestlandAges 20–40 - NCT07539311RecruitingPhase 2
Testing Rina-S for Advanced Gastrointestinal Cancers
This study tests a new drug called Rina-S in people with advanced gastrointestinal cancers (like stomach, colon, or pancreatic cancer) that have spread or cannot be surgically removed. The drug is designed to help slow or stop cancer growth in people whose cancer has gotten worse despite recent treatment.
Los Angeles, CaliforniaAges 18 years+ - NCT07479472Recruiting
A study of digestive tract cancers in young adults
This study observes people aged 18-49 with a new gastrointestinal cancer (colorectal, stomach/esophageal, or pancreatic) to learn how their lifestyle habits and tumor characteristics affect their health. By participating, you help researchers understand why these cancers occur in younger adults.
Bologna, BOAges 18–49 - NCT07585266RecruitingPhase 3
New drug velzatinib versus imatinib for untreated GIST
This trial compares a newer cancer drug (velzatinib) with a standard treatment (imatinib) for gastrointestinal stromal tumors (GIST) that cannot be surgically removed or have spread. You would receive one of these two drugs to see which works better and is safer.
Scottsdale, ArizonaAges 18 years+ - NCT07678970RecruitingPhase 1
Study of SI-B036 for advanced gastrointestinal and other solid tumors
This trial tests a new drug called SI-B036 in people with advanced digestive tract or other solid tumors that have spread. It aims to see if the drug is safe and effective. You may qualify if you have a measurable tumor and are in relatively good health.
Harbin, HeilongjiangAges 18–75 - NCT07865052Recruiting
Psychological support before complex stomach or intestinal surgery
This study tests whether a psychological program before major abdominal surgery can help reduce distress and improve recovery. Participants will receive extra mental health support to prepare for their operation.
Chicago, IllinoisAges 18 years+ - NCT07817758Recruiting
Sarcopenia and surgery outcomes in older gastrointestinal cancer patients
This trial looks at whether low muscle mass (sarcopenia) before surgery affects recovery for older adults with gastrointestinal cancer. It may help doctors personalize care and improve outcomes.
Van, VanAges 60 years+ - NCT07815392Recruiting
Frailty and recovery after gastrointestinal cancer surgery
This study looks at how frailty, or overall physical weakness, affects recovery after surgery for gastrointestinal cancer in people aged 60 and older. The findings may help doctors better prepare patients for surgery and improve their recovery.
Van, VanAges 60 years+ - NCT07763652RecruitingPhase 1
Study of BL-ARC002 for advanced gastrointestinal and other solid tumors
This trial tests an investigational drug called BL-ARC002 for people with advanced or metastatic cancers of the esophagus, stomach, colon, rectum, or other solid tumors. The goal is to see if it is safe and effective in treating these cancers.
Guangzhou, GuangdongAges 18 years+ - NCT07622849Enrolling by invitation
Fecal Microbiota Transplant for Transplant-Related Intestinal Damage
This trial tests whether transferring healthy gut bacteria from a donor to patients can help heal severe intestinal damage that occurs after bone marrow or stem cell transplants. The goal is to reduce pain, inflammation, and other complications from this serious side effect.
Suzhou, JiangsuAges 15–65
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Common questions
- Are there clinical trials for gastrointestinal?
- Yes. Clin2 currently lists 469 recruiting gastrointestinal studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a gastrointestinal trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a gastrointestinal trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.