Clinical trials
Gastrointestinal clinical trials
Below are recruiting gastrointestinal clinical trials, each written for real people, not researchers. We’re tracking 481 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07218926RecruitingPhase 3
New drug vs sunitinib for GIST after imatinib
This trial compares a new oral drug, IDRX-42, with the standard drug sunitinib (Sutent) for people with advanced GIST whose cancer has progressed after imatinib therapy. The goal is to see if IDRX-42 can better control the tumor growth.
Phoenix, ArizonaAges 18 years+ - NCT07232407RecruitingPhase 1
Study of a radioactive drug for advanced solid tumors
This trial tests a new radioactive drug (Lutetium-177 BL-ARC001) for people with advanced solid tumors, including stomach, bowel, and other cancers. It aims to see if the treatment is safe and how well it works.
Chengdu, SichuanAges 18 years+ - NCT07223255Recruiting
Mediterranean diet study for children with cystic fibrosis
This study tests whether a Mediterranean-style diet can improve gastrointestinal health in children with cystic fibrosis. It requires families to follow the diet for 6 months and attend regular clinic visits.
Lebanon, New HampshireAges 3–18 - NCT07252102Recruiting
High-flow oxygen during sedation for critical patients having GI endoscopy
This trial tests whether high-flow nasal oxygen (HFNC) reduces low oxygen levels during sedated gastrointestinal procedures. It is for patients with higher health risks (ASA grade III–IV) who need an endoscopy or treatment.
Shenzhen, GuangdongAges 18–80 - NCT07263594RecruitingPhase 1/Phase 2
Study of DB-1324 for advanced stomach or bowel cancers
This trial tests a new drug called DB-1324 for people with advanced gastrointestinal cancers that have stopped responding to standard treatments. It targets a protein called CDH17 on cancer cells to slow or shrink the tumor.
Port Saint Lucie, FloridaAges 18 years+ - NCT07279428RecruitingPhase 1
Study of BL-M24D1 for advanced digestive and other solid tumors
This trial tests a new drug, BL-M24D1, in people with advanced or metastatic digestive tract cancers or other solid tumors that have not responded to standard treatments. The goal is to see if it is safe and effective.
Beijing, Beijing MunicipalityAges 18 years+ - NCT07329894RecruitingPhase 1
XH001 and vaccine-activated T cells for advanced GI cancer
This trial tests a two-part treatment: an injection called XH001 plus a custom vaccine that trains your immune cells to attack tumors. It's for people with advanced stomach or bowel cancer that hasn't responded to at least two prior treatments.
BeijingAges 18–70 - NCT07333144Recruiting
Bleeding from the gut while on blood thinners
This study collects information from patients who come to the emergency room with gastrointestinal bleeding while taking certain newer blood thinners. It aims to better understand and manage this type of bleeding.
StrasbourgAges 18 years+ - NCT07379047RecruitingPhase 2/Phase 3
Testing NB003 for advanced GIST after prior treatments
This trial tests a new drug called NB003 for people with advanced GIST (a type of stomach or intestinal tumor) that has stopped responding to or could not be tolerated after standard treatments like imatinib or sunitinib. The goal is to see if NB003 can help shrink or control the tumor.
Hefei, AnhuiAges 18 years+ - NCT07383935Recruiting
Stress ball use during chemotherapy for GI cancer patients
This study tests whether using a stress ball during chemotherapy helps patients with gastrointestinal cancer feel better. It may reduce stress or discomfort during treatment.
ArtvinAges 18 years+ - NCT01048281Recruiting
Study of stomach and esophagus cancer samples
This study looks at stomach (gastric) and esophagus cancer, using clinical information and tissue samples. It may help researchers better understand these cancers and improve future care.
Stanford, CaliforniaAges 18 years+ - NCT01750619Recruiting
Endoscopic removal of early and cancer GI growths
This trial looks at outcomes after doctors remove abnormal or cancerous growths in the digestive tract using an endoscope (a flexible camera passed through the body). It may help improve how safely and effectively these procedures are done.
San Francisco, CaliforniaAges 18 years+ - NCT02523118Recruiting
Measuring symptoms and test results in eosinophilic gut diseases
This study looks at how eosinophilic inflammation in the esophagus and intestines affects outcomes like symptoms and test findings. It may help clinicians better understand these conditions and track what changes over time.
Phoenix, ArizonaAges 3 years+ - NCT07056777RecruitingPhase 1/Phase 2
DR30206 plus standard therapy for advanced GI cancer
This trial tests a new drug called DR30206 combined with standard therapy for advanced gastrointestinal cancers. It may be an option if you have colorectal, esophageal, gastric, or gastroesophageal junction cancer and have had little or no prior chemotherapy.
Guangzhou, GuangdongAges 18–75 - NCT07467213RecruitingPhase 3
Acid reflux drug for heart attack recovery
This trial tests if a newer acid-reducing drug is better than standard care for preventing stomach problems in people who recently had a heart attack and a stent placed. It could help those who need stomach protection while on blood thinners.
SeoulAges 19 years+ - NCT06427798RecruitingPhase 1/Phase 2
Radioactive drug for previously treated gut or adrenal tumors
This trial tests a new radioactive drug, [212Pb]VMT-alpha-NET, that targets a receptor found on some tumor cells. It is for people with certain gut or adrenal gland tumors that have already been treated with a similar therapy but are still growing.
Bethesda, MarylandAges 18–120 - NCT07559864RecruitingPhase 2
Regorafenib plus Envafolimab for treatment-resistant gastrointestinal stromal tumors
This study tests a combination of two drugs (regorafenib and envafolimab) for gastrointestinal stromal tumors (a type of stomach/bowel cancer) that have stopped responding to standard treatments. The trial compares this combination to other doctor-selected treatments to see if it slows tumor growth.
Beijing, Beijing MunicipalityAges 18 years+ - NCT07561840Recruiting
Exercise Training After Stomach or Esophagus Cancer Surgery
This study tests whether a guided exercise program helps people recover better after surgery for esophageal or gastric (stomach) cancer. Researchers will track your strength, fitness, and quality of life over time.
Hirakata, OsakaAges 18 years+ - NCT07586813RecruitingPhase 2
Romiplostim N01 Plus ATRA for Low Platelets After Gut Cancer
This trial tests a combination of two medicines (Romiplostim N01 and ATRA) to raise dangerously low platelet counts that sometimes persist after chemotherapy for digestive cancers. If your platelets stay low even after previous platelet-raising treatments, this study may help.
BeijingAges 18 years+ - NCT07664228Recruiting
Predicting stomach pain in children with IgA vasculitis
This study looks at a blood test done when a child is first diagnosed with IgA vasculitis (also called Henoch-Schönlein purpura) to see if it can predict stomach or intestine problems. It involves one extra blood draw at diagnosis and a follow-up visit a few weeks later.
Bursa, BursaAges 2–18 - NCT07550582Enrolling by invitationPhase 2
Surgery for small tumors at the food pipe opening
This trial tests a new surgical approach combining laparoscopic (minimally invasive) surgery with endoscopy (a camera procedure) to remove small tumors located where the esophagus meets the stomach. The goal is to safely remove these tumors while preserving normal function.
Beijing, Beijing MunicipalityAges 18–80 - NCT07050485Enrolling by invitation
Postbiotic gummies after GI cancer surgery
This trial tests if taking postbiotic gummies (a type of supplement that helps good gut bacteria) can help your gut recover faster after surgery for stomach, colon, or other gastrointestinal cancers. It is for people having scheduled, minimally invasive (laparoscopic) surgery to remove their cancer.
Tampa, FloridaAges 18 years+ - NCT06951490Enrolling by invitation
PillSense study for anemia and blood in stool
This trial tests a special pill that can be swallowed to help find the cause of anemia or hidden blood in the stool, without the need for more invasive tests. It is for patients who are already in the hospital and have been referred to a gastroenterologist.
Orlando, FloridaAges 18 years+ - NCT06679478Enrolling by invitation
Early walking after stomach or bowel surgery
This study tests whether a structured early walking plan helps people recover faster after open gastrointestinal surgery. You will use a phone app to track your steps.
KütahyaAges 18–80
Hear when a new Gastrointestinal trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.
Common questions
- Are there clinical trials for gastrointestinal?
- Yes. Clin2 currently lists 481 recruiting gastrointestinal studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a gastrointestinal trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a gastrointestinal trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.